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Nutrition: Vitamin B
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Total 34 results found since Jan 2013.
The Controversial Role of HCY and Vitamin B Deficiency in Cardiovascular Diseases
Nutrients. 2022 Mar 28;14(7):1412. doi: 10.3390/nu14071412.ABSTRACTPlasma homocysteine (HCY) is an established risk factor for cardiovascular disease CVD and stroke. However, more than two decades of intensive research activities has failed to demonstrate that Hcy lowering through B-vitamin supplementation results in a reduction in CVD risk. Therefore, doubts about a causal involvement of hyperhomocysteinemia (HHcy) and B-vitamin deficiencies in atherosclerosis persist. Existing evidence indicates that HHcy increases oxidative stress, causes endoplasmatic reticulum (ER) stress, alters DNA methylation and, thus, modulates t...
Source: Atherosclerosis - April 12, 2022 Category: Cardiology Authors: Wolfgang Herrmann Markus Herrmann Source Type: research
Hyperhomocysteinemia in cardiovascular diseases: revisiting observational studies and clinical trials
In conclusion, revisiting observational studies and clinical trials suggests that cardiovascular patients should be screened for hyperhomocysteinemia, when no other risk factor is found. Patients with intermediate/major hyperhomocysteinemia should be properly assessed and treated for vitamin B deficiencies and inherited disorders according to current guidelines. Further trials are needed to assess the lowering homocysteine effect according to hyperhomocysteinemia categories at baseline.PMID:36170884 | DOI:10.1055/a-1952-1946
Source: Thrombosis and Haemostasis - September 28, 2022 Category: Hematology Authors: Jean-Louis Gueant Rosa-Maria Gueant-Rodriguez Abderrahim Oussalah Stephane Zuily Irwin Rosenberg Source Type: research
Early Detection of Subclinical Atherosclerosis: Hyperhomocysteinemia as a Promising Marker in Adolescents With Vitamin B Deficiency
Cureus. 2023 Jul 8;15(7):e41571. doi: 10.7759/cureus.41571. eCollection 2023 Jul.ABSTRACTIn recent decades, the increased incidence of cardiovascular disease (CVD) mortality among young adults has raised concerns. Although clinical manifestations of CVD typically occur later in life, the underlying pathological processes emerge early on. This review article summarizes the association between vitamin B deficiency-induced hyperhomocysteinemia and subclinical atherosclerosis in adolescents. Numerous studies have demonstrated that elevated homocysteine levels are an independent risk factor for endothelial dysfunction (ED) and ...
Source: Atherosclerosis - August 9, 2023 Category: Cardiology Authors: Parth S Shirode Anjali D Parekh Vishwa V Patel Janmay Vala Aniket M Jaimalani Nilofar M Vora Vaishnavi Gummalla Jaineel S Patel Nikitha Shriram Source Type: research
