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Exit Strategy: Planning for the Unexpected Closure of Your Practice
Conclusion Once drafted, your plan should be regularly updated to reflect changes in your practice and the practices of the colleagues who have agreed to assist in an emergency. Remember to include contact information for others who may be able to assist your family and/or staff, such as your malpractice carrier and your business attorney. The plan need not be complex, but it must be documented and readily available to anyone who may need to implement it. Your patients, your staff, and your family will thank you for it.
Source: Innovations in Clinical Neuroscience - June 1, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Current Issue Practice Management Psychiatry Risk Management exit strategy office closing Source Type: research

The Neuroscience Report—Volume 44 (July 19, 2016): What’s Hot in Neuroimaging?
The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s topic: What’s Hot in Neuroimaging? Journal Articles How Can Neuroimaging Facilitate the Diagnosis and Stratification of Patients with Psychosis? Functional Neuroimaging of Traumatic Brain Injury: Advances and Clinical Utility MRI Evalu...
Source: Innovations in Clinical Neuroscience - July 19, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Assessment Tools Devices Drug Development EEG Genetics Neurology Psychiatry Technology The Neuroscience Report computed tomography electroencephalogram functional magnetic resonance imaging Magnetoencephalography neuroimaging P Source Type: research

The Neuroscience Report —Volume 44 (July 19, 2016): What ’ s Hot in Neuroimaging?
The latest in neuroscience—sorted and summarized for you Welcome to The Neuroscience Report where each week we will highlight a specific topic in neuroscience and provide you with links to 5 journal articles, 5 news articles, and 5 wildcard picks. Brought to you by Innovations in Clinical Neuroscience—your source for peer-reviewed, evidence-based information. This week’s topic: What’s Hot in Neuroimaging? Journal Articles How Can Neuroimaging Facilitate the Diagnosis and Stratification of Patients with Psychosis? Functional Neuroimaging of Traumatic Brain Injury: Advances and Clinical Utility MRI Evalu...
Source: Innovations in Clinical Neuroscience - July 19, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Assessment Tools Devices Drug Development EEG Genetics Neurology Psychiatry Technology The Neuroscience Report computed tomography electroencephalogram functional magnetic resonance imaging Magnetoencephalography neuroimaging P Source Type: research

Ketamine Therapy for Treatment-resistant Depression in a Patient with Multiple Sclerosis: A Case Report
Conclusion—Ketamine may be an alternative treatment for resistant depression and may have a special use in patients with multiple sclerosis. Introduction Depression is a frequent finding in patients with multiple sclerosis (MS), with the lifetime prevalence rates for major depressive disorder (MDD) ranging from 36 to 54 percent, more than twice of that in the general population.[1] Even with advances in pharmacological options for treating depression, an estimated 33 to 66 percent of patients with MDD in the general population do not respond to the first antidepressant, and a reported 15 to 33 percent of patients do not ...
Source: Innovations in Clinical Neuroscience - February 1, 2017 Category: Neuroscience Authors: ICN Online Editor Tags: Case Report Current Issue Depression Multiple Sclerosis Neurology Psychiatry Psychopharmacology Electroconvulsive therapy Ketamine major depressive disorder treatment-resistant depression Source Type: research

CNS Summit 2016 Abstracts of Poster Presentations
Conclusion: Subjects with acutely exacerbated schizophrenia who were eligible for discharge from the inpatient setting and who completed the study demonstrated high rates of adherence using the mobile AI application. Subjects were able to easily use the technology. Use of the platform did not appear to increase the dropout rate. This study demonstrates the feasibility of using AI platforms to ensure high adherence, provide reliable adherence data, and rapidly detect nonadherence in CNS trials. Disclosures/funding: Adam Hanina and Laura Shafner are employees of AiCure, New York, New York, and consultants to Takeda. Xinxin D...
Source: Innovations in Clinical Neuroscience - February 1, 2017 Category: Neuroscience Authors: ICN Online Editor Tags: Assessment Tools biomarkers Cognition Current Issue Devices Drug Development Evaluations Genetics Medical Issues Neurology Patient Assessment Proceedings Psychiatry Psychopharmacology Scales Supplements Technology Trial M Source Type: research

Lower-extremity Dynamometry as a Novel Outcome Measure in a Double-blind, Placebo-controlled, Feasibility Trial of Intravenous Immunoglobulin (IVIG) for HIV-associated Myelopathy
Conclusion: We conclude that an adequately powered clinical trial of IVIG for HIVM would likely require a prolonged recruitment period and multiple participating sites. Lower limb dynamometry is a useful outcome measure for HIVM, which might also be useful in other HIV-related gait disorders. KEYWORDS: Dynamometry, intravenous immunoglobulin (IVIG), human immunodeficiency virus (HIV), myelopathy INTRODUCTION Human immunodeficiency virus (HIV)-associated myelopathy (HIVM) is a rare but well-described neurologic complication of HIV; it was first described early in the acquired immunodeficiency syndrome (AIDS) epidemic, and i...
Source: Innovations in Clinical Neuroscience - February 1, 2018 Category: Neuroscience Authors: ICN Online Editor Tags: Assessment Tools Current Issue Demyelinating Disease Movement Disorders Neurodegenerative Disease Neurology Original Research Primary Care Technology Trial Methodology Dynamometry human immunodeficiency virus (HIV) intravenous immu Source Type: research

Neuroscience is the Next Oncology
by Michael D. Ehlers, MD, PhD Dr. Ehlers is with Biogen in Cambridge, Massachusetts. Innov Clin Neurosci. 2018;15(3–4):15–16 Funding: No funding was received for the preparation of this article. Disclosures: Dr. Ehlers is an employee and shareholder at Biogen Inc. in Cambridge, Massachusetts. Prominent and expensive failures in Alzheimer’s disease therapies have led to a contagious belief system in some parts of the biopharma industry that neuroscience is just too hard, too risky, and too uncertain. But, might this belief system itself be a residual bias of the past? Close inspection reveals all the signs of a coming...
Source: Innovations in Clinical Neuroscience - April 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Commentary Current Issue Source Type: research