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Source: American Journal of Translational Research

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Total 1330 results found since Jan 2013.

Blood biomarkers for physical recovery in ischemic stroke: a systematic review.
Authors: Lai YJ, Hanneman SK, Casarez RL, Wang J, McCullough LD Abstract Stroke is a common cause of physical disability. Biomarkers have been used to predict prognosis in ischemic stroke, but studies linking biomarkers to physical recovery from ischemic stroke have not been systematically evaluated since 2011. The purpose of this paper is to report the findings of a systematic review of the intervening literature to identify potential predictive biomarkers for recovery of physical function following ischemic stroke. The PubMed, Embase, and CINAHL databases were searched for studies reported between January 1, 2011...
Source: American Journal of Translational Research - September 11, 2019 Category: Research Tags: Am J Transl Res Source Type: research

Network pharmacology of Huatan Tongluo decoction and clinical effects of its combination with acupuncture in the treatment of stroke
CONCLUSION: The combination of Huatan Tongluo decoction and acupuncture can help patients with sequelae of stroke promote the regaining of neurological function, thus improving their movement and enhancing their abilities to perform daily living. Huatan Tongluo decoction can mediate the VEGF signaling pathway and other pathways to treat ischemic stroke.PMID:36505343 | PMC:PMC9730069
Source: American Journal of Translational Research - December 12, 2022 Category: Research Authors: Fangli Hou Hua Liu Quanyou Gong Haiyang Xu Source Type: research

Exosomes from miRNA-126-modified ADSCs promotes functional recovery after stroke in rats by improving neurogenesis and suppressing microglia activation.
Authors: Geng W, Tang H, Luo S, Lv Y, Liang D, Kang X, Hong W Abstract Although adipose derived stem cells (ADSCs) exert their therapeutic potential in ischemic stroke, the migration of ADSCs in injured area is not apparently observed after intravenous administration. ADSCs are an important source of exosomes which hold great promise as an endogenous drug delivery system for the treatment of cerebral ischemia given their ability to cross the blood-brain barrier. Here we investigated whether ADSCs-derived exosomes mediated miRNAs transfer and thus promoted neurological recovery after stroke. We first proved that miR...
Source: American Journal of Translational Research - March 24, 2019 Category: Research Tags: Am J Transl Res Source Type: research