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Source: NeuroImage: Clinical

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Total 156 results found since Jan 2013.

Assessment of longitudinal hippocampal atrophy in the first year after ischemic stroke using automatic segmentation techniques
Publication date: Available online 22 October 2019Source: NeuroImage: ClinicalAuthor(s): Mohamed Salah Khlif, Emilio Werden, Natalia Egorova, Marina Boccardi, Alberto Redolfi, Laura Bird, Amy BrodtmannAbstractWe assessed first-year hippocampal atrophy in stroke patients and healthy controls using manual and automated segmentations: AdaBoost, FIRST (fsl/v5.0.8), FreeSurfer/v5.3 and v6.0, and Subfields (in FreeSurfer/v6.0). We estimated hippocampal volumes in 39 healthy controls and 124 stroke participants at three months, and 38 controls and 113 stroke participants at one year. We used intra-class correlation, concordance, ...
Source: NeuroImage: Clinical - October 24, 2019 Category: Radiology Source Type: research

Structurofunctional resting-state networks correlate with motor function in chronic stroke
Conclusion The results demonstrate that changes after a stroke in both intrinsic and network-based structurofunctional correlations at rest are correlated with motor function, underscoring the importance of residual structural connectivity in cortical networks.
Source: NeuroImage: Clinical - July 29, 2017 Category: Radiology Source Type: research

Comparing a diffusion tensor and non-tensor approach to white matter fiber tractography in chronic stroke
Publication date: Available online 14 March 2015 Source:NeuroImage: Clinical Author(s): A.M. Auriat , M.R. Borich , N.J. Snow , K.P. Wadden , L.A. Boyd Diffusion tensor imaging (DTI)-based tractography has been used to demonstrate functionally relevant differences in white matter pathway status after stroke. However, it is now known that the tensor model is insensitive to the complex fiber architectures found in the vast majority of voxels in the human brain. The inability to resolve intra-voxel fiber orientations may have important implications for the utility of standard DTI-based tract reconstruction methods. Intra-vo...
Source: NeuroImage: Clinical - March 14, 2015 Category: Radiology Source Type: research

Bihemispheric alterations in myelination in children following unilateral perinatal stroke
Conclusion Myelination of apparently uninjured brain in both the ipsilesional and contralesional hemispheres is decreased after perinatal stroke. Differences appear to radiate outward from the lesion. Further study is needed to determine clinical significance.
Source: NeuroImage: Clinical - June 28, 2018 Category: Radiology Source Type: research

A comparison of automated segmentation and manual tracing in estimating hippocampal volume in ischemic stroke and healthy control participants
Publication date: Available online 22 October 2018Source: NeuroImage: ClinicalAuthor(s): Mohamed Salah Khlif, Natalia Egorova, Emilio Werden, Alberto Redolfi, Marina Bocardi, Charles S. DeCarli, Even Fletcher, Baljeet Singh, Qi Li, Laura Bird, Amy BordtmannAbstractManual quantification of the hippocampal atrophy state and rate is time consuming and prone to poor reproducibility, even when performed by neuroanatomical experts. The automation of hippocampal segmentation has been investigated in normal aging, epilepsy, and in Alzheimer's disease. Our first goal was to compare manual and automated hippocampal segmentation in i...
Source: NeuroImage: Clinical - October 22, 2018 Category: Radiology Source Type: research

Hypercapnic evaluation of vascular reactivity in healthy aging and acute stroke via functional MRI
Publication date: Available online 25 June 2016 Source:NeuroImage: Clinical Author(s): Ryan V. Raut, Veena A. Nair, Justin A. Sattin, Vivek Prabhakaran Functional MRI (fMRI) is well-established for the study of brain function in healthy populations, though its clinical application has proven more challenging. Specifically, cerebrovascular reactivity (CVR), which allows the assessment of the vascular response that serves as the basis for fMRI, has been shown to be reduced in healthy aging as well as in a range of diseases, including chronic stroke. However, the timing of when this occurs relative to the stroke event i...
Source: NeuroImage: Clinical - June 24, 2016 Category: Radiology Source Type: research

Parietofrontal network upregulation after motor stroke
Publication date: Available online 7 March 2018 Source:NeuroImage: Clinical Author(s): M. Bönstrup, R. Schulz, G. Schoen, B. Cheng, J. Feldheim, G. Thomalla, C. Gerloff Objective Motor recovery after stroke shows a high inter-subject variability. The brain's potential to form new connections determines individual levels of recovery of motor function. Most of our daily activities require visuomotor integration, which engages parietal areas. Compared to the frontal motor system, less is known about the parietal motor system's reconfiguration related to stroke recovery. Here, we tested if functional connectivity among parie...
Source: NeuroImage: Clinical - March 8, 2018 Category: Radiology Source Type: research

Disrupted functional network integrity and flexibility after stroke: Relation to motor impairments
Publication date: Available online 9 June 2018 Source:NeuroImage: Clinical Author(s): Sara Larivière, Nick S. Ward, Marie-Hélène Boudrias Previous studies investigating brain activation present during upper limb movement after stroke have greatly detailed activity alterations in the ipsi- and contralesional primary motor cortices (M1). Despite considerable interest in M1, investigations into the integration and coordination of large-scale functional networks subserving motor, sensory, and cognitive control after stroke remain scarce. The purpose of this study was to assess non-static functional connectivity within whol...
Source: NeuroImage: Clinical - June 9, 2018 Category: Radiology Source Type: research

Bihemispheric alterations in myelination in children following unilateral perinatal stroke
ConclusionMyelination of apparently uninjured brain in both the ipsilesional and contralesional hemispheres is decreased after perinatal stroke. Differences appear to radiate outward from the lesion. Further study is needed to determine clinical significance.
Source: NeuroImage: Clinical - July 5, 2018 Category: Radiology Source Type: research

Disrupted functional network integrity and flexibility after stroke: Relation to motor impairments
Publication date: 2018Source: NeuroImage: Clinical, Volume 19Author(s): Sara Larivière, Nick S. Ward, Marie-Hélène BoudriasAbstractPrevious studies investigating brain activation present during upper limb movement after stroke have greatly detailed activity alterations in the ipsi- and contralesional primary motor cortices (M1). Despite considerable interest in M1, investigations into the integration and coordination of large-scale functional networks subserving motor, sensory, and cognitive control after stroke remain scarce. The purpose of this study was to assess non-static functional connectivity within whole-brain ...
Source: NeuroImage: Clinical - July 5, 2018 Category: Radiology Source Type: research

Bihemispheric alterations in myelination in children following unilateral perinatal stroke
ConclusionMyelination of apparently uninjured brain in both the ipsilesional and contralesional hemispheres is decreased after perinatal stroke. Differences appear to radiate outward from the lesion. Further study is needed to determine clinical significance.
Source: NeuroImage: Clinical - July 19, 2018 Category: Radiology Source Type: research

Thalamic diaschisis following perinatal stroke is associated with clinical disability
ConclusionBilateral thalamic volume changes occur after perinatal stroke. Ipsilesional volume loss is not associated with clinical motor function. Contralesional volume is inversely correlated with clinical motor function, suggesting the thalamus is involved in the known developmental plasticity that occurs in the contralesional hemisphere after early unilateral injury.
Source: NeuroImage: Clinical - January 5, 2019 Category: Radiology Source Type: research

Structural covariance in subcortical stroke patients measured by automated MRI-based volumetry
Publication date: Available online 22 January 2019Source: NeuroImage: ClinicalAuthor(s): Caihong Wang, Lei Zhao, Yishan Luo, Jingchun Liu, Peifang Miao, Sen Wei, Lin Shi, Jingliang ChengAbstractA network-level investigation of the volumetric changes of subcortical stroke patients is still lacking. Here, we explored the alterations of structural covariance caused by subcortical stroke with automated brain volumetry. T1-weighed brain MRI scans were obtained from 63 normal controls (NC), 46 stroke patients with infarct in left internal capsule (CI_L), 33 stroke patients with infarct in right internal capsule (CI_R). We perfor...
Source: NeuroImage: Clinical - January 22, 2019 Category: Radiology Source Type: research

Recovery of slow-5 oscillations in a longitudinal study of ischemic stroke patients
In this study, we characterized longitudinally the changes in the slow-5 oscillations in stroke patients across two different time-points. We followed a group of ischemic stroke patients (n =20) and another group of healthy older adults (n =14) over two visits separated by a minimum of three months (average of 9months). For the stroke patients, one visit occurred in their subacute window (10days to 6months after stroke onset), the other took place in their chronic window (>6months after stroke). Using a mid-order group ICA method on 10-minutes eyes-closed resting-state fMRI data, we assessed the frequency distributi...
Source: NeuroImage: Clinical - March 17, 2016 Category: Radiology Source Type: research