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Association of diabetes with stroke and post-stroke dementia: A population-based cohort study.
DISCUSSION: Diabetes, but not prediabetes, is associated with an increased risk of ischemic stroke and post-stroke dementia. PMID: 32489021 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - June 4, 2020 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Increased risk for dementia both before and after stroke: A population-based study in women followed over 44  years.
DISCUSSION: There is an increased risk for dementia both before and after stroke. This has implications for understanding the relation between the two disorders and for prevention of dementia and stroke. PMID: 29936145 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - June 25, 2018 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Stroke and dementia risk: A systematic review and meta-analysis.
DISCUSSION: Stroke is a strong, independent, and potentially modifiable risk factor for all-cause dementia. PMID: 30177276 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - September 6, 2018 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Preventing dementia by preventing stroke: The Berlin Manifesto.
This article summarizes the evidence for translation into action. PMID: 31327392 [PubMed - in process]
Source: The Journal of Alzheimers Association - July 24, 2019 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Prevalent stroke, age of its onset, and post-stroke lifestyle in relation to dementia: A prospective cohort study
DISCUSSION: Stroke onset in earlier life stage predicted a higher risk for dementia, but a favorable post-stroke lifestyle may protect against dementia.PMID:37157186 | DOI:10.1002/alz.13122
Source: The Journal of Alzheimers Association - May 9, 2023 Category: Psychiatry Authors: Wansi Zhong Hui Chen Xiaoxian Gong Lusha Tong Xin Xu Geng Zong Changzheng Yuan Min Lou Source Type: research

Population-based stroke and dementia incidence trends: Age and sex variations.
This study explores these trends within demographic subgroups. METHODS: We analyzed administrative data sources using validated algorithms to calculate stroke and dementia incidence rates from 2002 to 2013. RESULTS: For more than 12 years, stroke incidence remained unchanged among those aged 20 to 49 years and decreased for those aged 50 to 64, 65 to 79, and 80+ years by 22.7%, 36.9%, and 37.9%, respectively. Dementia incidence increased by 17.3% and 23.5% in those aged 20 to 49 and 50 to 64 years, respectively, and remained unchanged in those aged 65 to 79 years and decreased by 15.4% in those aged 80+ years. ...
Source: The Journal of Alzheimers Association - April 2, 2017 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Cerebral small vessel disease burden and cognitive and functional outcomes after stroke: A multicenter prospective cohort study
DISCUSSION: SVD presence and severity are associated with worse cognitive and functional outcomes 12 months after stroke. Assessing SVD severity may aid prognostication for stroke patients.HIGHLIGHTS: In a multi-center cohort, we explored associations of small vessel disease (SVD) burden with stroke outcomes. SVD burden associates with post-stroke cognitive and functional outcomes. A currently used score of SVD burden does not improve the prediction of poor outcomes. Assessing the severity of SVD lesions adds predictive value beyond known predictors. To add predictive value in assessing SVD in stroke patients, SVD burden s...
Source: The Journal of Alzheimers Association - July 25, 2022 Category: Psychiatry Authors: Marios K Georgakis Rong Fang Marco D üring Frank A Wollenweber Felix J Bode Sebastian St össer Christine Kindlein Peter Hermann Thomas G Liman Christian H Nolte Lucia Kerti Benno Ikenberg Kathleen Bernkopf Holger Poppert Wenzel Glanz Valentina Perosa Da Source Type: research

Delayed-onset dementia after stroke or transient ischemic attack.
DISCUSSION: Severe SVD contributes importantly to delayed-onset dementia after stroke and/or TIA. Future clinical trials aiming to prevent delayed-onset dementia after stroke and/or TIA should target this high-risk group. PMID: 27327542 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - June 23, 2016 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Acetylcholinesterase inhibitors and risk of stroke and death in people with dementia.
DISCUSSION: The use of AChEIs in people with dementia may be associated with reduced risk of ischemic stroke and death. These results call for a closer examination of the cardiovascular effects of AChEIs. PMID: 29706487 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - May 2, 2018 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Stroke and dementia, leading causes of neurological disability and death, potential for prevention
We report the 2019 estimations for global disability-adjusted life years (DALYs) and death numbers and rates related to stroke and dementia, as well as their risk attributed DALYs and deaths and their changes between 2010 and 2019.RESULTS: Stroke accounted for 69.8%, dementia for 17.3%, and combined contributed to 87.2% (8.2 million) of neurological deaths and 61.7% (168.5 million) of neurological DALYs in 2019. For stroke, 86.4% of DALYs and for dementias 32.8% of DALYs are attributable to risk factors. Globally, hypertension (54.8%) and unhealthy diet (30.0%) pose the greatest risk for stroke DALYs, and smoking (15.1%) a...
Source: The Journal of Alzheimers Association - May 31, 2021 Category: Psychiatry Authors: Abolfazl Avan Vladimir Hachinski Source Type: research

Risk factors for incident dementia after stroke and transient ischemic attack.
CONCLUSIONS: Chronic brain changes including WMCs, MTLA, and AD pathology are associated with incident dementia after stroke/TIA. Interventions targeting these chronic brain changes may reduce burden of vascular cognitive impairment. PMID: 24603162 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - March 10, 2014 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

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