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Source: IEEE Transactions on Biomedical Engineering

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Total 85 results found since Jan 2013.

Optogenetic Excitation of Ipsilesional Sensorimotor Neurons is Protective in Acute Ischemic Stroke: A Laser Speckle Imaging Study
Conclusion: Excitatory stimulation of ipsilesional sensorimotor neurons in an acute stroke could protect neurovascular function and reduces the expansion of ischemic area. Significance: For the first time, this work demonstrates that specific neuronal modulation in the acute stroke is neuroprotective and reduces the infarct size.
Source: IEEE Transactions on Biomedical Engineering - April 23, 2019 Category: Biomedical Engineering Source Type: research

Novel Electrode Placement in Electrical Bioimpedance-Based Stroke Detection: Effects on Current Penetration and Injury Characterization in a Finite Element Model
Conclusion: These findings support the use of novel electrode placements in EBI to overcome prior limitations, indicating a potential approach to increasing the technology's clinical utility in stroke identification. Significance: A non-invasive EBI monitor for stroke could provide essential timely intervention an- care of stroke patients.
Source: IEEE Transactions on Biomedical Engineering - April 22, 2022 Category: Biomedical Engineering Source Type: research

Decoding Upper Limb Movement Attempt From EEG Measurements of the Contralesional Motor Cortex in Chronic Stroke Patients
Conclusion: This study showed that it is possible to construct a decoder of the attempt to move the paretic arm for chronic stroke patients using the EEG activity of the healthy contralesional motor cortex. Significance: This decoding model could provide to stroke survivors with a natural, easy, and intuitive way to achieve control of BCIs or robot-assisted rehabilitation devices.
Source: IEEE Transactions on Biomedical Engineering - December 23, 2016 Category: Biomedical Engineering Source Type: research

Myoelectric Pattern Recognition for Controlling a Robotic Hand: A Feasibility Study in Stroke
Conclusion: The findings suggest that it is feasible to apply myoelectric pattern recognition to control the robotic hand in some but not all of the stroke patients. Each stroke subject should be individually online tested for the feasibility of applying myoelectric pattern recognition control for robot-assisted rehabilitation.
Source: IEEE Transactions on Biomedical Engineering - January 22, 2019 Category: Biomedical Engineering Source Type: research

Correlation Evaluation of Functional Corticomuscular Coupling With Abnormal Muscle Synergy After Stroke
Conclusion: We developed a computational procedure to evaluate the correlation between fCMC and MSM in stroke patients. Significance: This article provides a quantitative evaluation metrics based on fCMC to reveal the deficits during poststroke motor restoration and a promising approach to help patients correct abnormal movement habits, paving the way for neurophysiological assessment of neuromuscular control in conjunction with clinical scores.
Source: IEEE Transactions on Biomedical Engineering - October 29, 2021 Category: Biomedical Engineering Source Type: research

Motor Impairment in Stroke Patients Is Associated With Network Properties During Consecutive Motor Imagery
Conclusion: These findings demonstrate that network properties based on functional and causal connectivity were highly associated with motor function in stroke patients. Significance: Our network properties can help calculate the predictor of motor impairments in stroke rehabilitation and provide insight into the neural correlates related to motor function based on EEG after reorganization induced by stroke.
Source: IEEE Transactions on Biomedical Engineering - July 19, 2022 Category: Biomedical Engineering Source Type: research

FES Cycling in Stroke: Novel Closed-Loop Algorithm Accommodates Differences in Functional Impairments
Conclusion: Using FES and an electric motor with a two-sided cadence control objective to assist and resist volitional efforts enabled stroke patients with varying strength and abilities to pedal within a desired cadence range. Significance: A protocol design that constrains volitional movements with assistance and resistance from FES and a motor shows potential for FES cycles and other rehabilitation robots during stroke rehabilitation.
Source: IEEE Transactions on Biomedical Engineering - February 21, 2020 Category: Biomedical Engineering Source Type: research

Assessment of the Efficacy of EEG-Based MI-BCI With Visual Feedback and EEG Correlates of Mental Fatigue for Upper-Limb Stroke Rehabilitation
Conclusion: nBETTER, an EEG-based MI-BCI employing only visual feedback, helps stroke survivors sustain short-term FMA improvement. Analysis of EEG relative beta power indicates that mental fatigue may be present. Significance: This study adds nBETTER to the growing literature of safe and effective stroke rehabilitation MI-BCI, and suggests an additional fatigue-monitoring role in future such BCI.
Source: IEEE Transactions on Biomedical Engineering - February 21, 2020 Category: Biomedical Engineering Source Type: research

Brain-Computer Interface-Based Soft Robotic Glove Rehabilitation for Stroke
Conclusion: BCI-SRG suggested probable trends of sustained functional improvements with peculiar kinesthetic experience outlasting active intervention in chronic stroke despite the dire need for large-scale investigations to verify statistical significance. Significance: Addition of BCI to soft robotic training for ADL-oriented stroke rehabilitation holds promise for sustained improvements as well as elicited perception of motor movements.
Source: IEEE Transactions on Biomedical Engineering - November 20, 2020 Category: Biomedical Engineering Source Type: research

Motor Unit Number Estimation in Spastic Biceps Brachii Muscles of Chronic Stroke Survivors Before and After BoNT Injection
Conclusions: The HDWA MUNE technique can be employed to characterize the motor unit loss in spastic muscle caused by upper motor neuro lesions at contraction level up to 30% MVC, but may fail to detect the MU loss caused by the chemodenervation effect of BoNT due to the non-uniform denervation of small and large size MUs. Significance: This study presents the first effort to evaluate the applicability of HDWA MUNE technique to characterize the MU loss in the spastic muscle following stroke and the subsequent BoNT injection for the treatment of post-stroke spasticity. The finding of this study suggests that HDWA MUNE...
Source: IEEE Transactions on Biomedical Engineering - February 21, 2023 Category: Biomedical Engineering Source Type: research

A Damper Driven Robotic End-Point Manipulator for Functional Rehabilitation Exercises After Stroke
Stroke survivors may benefit from robotic assistance for relearning of functional movements. Current assistive devices are either passive, limited to only two dimensions or very powerful. However, for reach training, weight compensation and a little assistance with limited power is sufficient. We designed and evaluated a novel three-dimensional robotic manipulator, which is able to support the arm weight and assist functional reaching movements. Key points of the design are a damper-based drive train, giving an inherently safe system and its compact and lightweight design. The system is force actuated with a bandwidth of u...
Source: IEEE Transactions on Biomedical Engineering - September 19, 2014 Category: Biomedical Engineering Source Type: research

Tactile Stimulation Improves Sensorimotor Rhythm-Based BCI Performance in Stroke Patients
Conclusion: This finding demonstrates that sensory afferent input from peripheral nerves benefits the neural process of sensorimotor cortex in stroke patients. With appropriate sensory stimulation, MRCA is enhanced and corresponding brain patterns are more discriminative. Significance: This novel SMR-BCI paradigm shows great promise to facilitate the practical application of BCI-based stroke rehabilitation.
Source: IEEE Transactions on Biomedical Engineering - June 25, 2019 Category: Biomedical Engineering Source Type: research

A Mathematical Model of Cellular Metabolism During Ischemic Stroke and Hypothermia
Stroke is a major cause of death and disability worldwide. Therapeutic hypothermia is a potentially useful neuroprotective treatment. A mathematical model of brain metabolism during stroke is extended here to simulate the effect of hypothermia on cell survival. Temperature decreases were set to reduce chemical reaction rates and slow diffusion through ion channels according to the $Q_{10}$ rule. Heat delivery to tissues was set to depend on metabolic heat generation rate and perfusion. Two cooling methods, scalp and vascular, were simulated to approximate temperature variation in the brain during treatment. Cell death was ...
Source: IEEE Transactions on Biomedical Engineering - January 17, 2014 Category: Biomedical Engineering Source Type: research

Microwave-Based Stroke Diagnosis Making Global Prehospital Thrombolytic Treatment Possible
Here, we present two different brain diagnostic devices based on microwave technology and the associated two first proof-of-principle measurements that show that the systems can differentiate hemorrhagic from ischemic stroke in acute stroke patients, as well as differentiate hemorrhagic patients from healthy volunteers. The system was based on microwave scattering measurements with an antenna system worn on the head. Measurement data were analyzed with a machine-learning algorithm that is based on training using data from patients with a known condition. Computer tomography images were used as reference. The detection meth...
Source: IEEE Transactions on Biomedical Engineering - October 17, 2014 Category: Biomedical Engineering Source Type: research

Examination of Hand Muscle Activation and Motor Unit Indices Derived from Surface EMG in Chronic Stroke
In this study, we used muscle and motor unit indices, derived from convenient surface electromyography (EMG) measurements, for examination of paretic muscle changes post stroke. For 12 stroke subjects, compound muscle action potential and voluntary surface EMG signals were recorded from paretic and contralateral first dorsal interosseous, abductor pollicis brevis, and abductor digiti minimi muscles. Muscle activation index (AI), motor unit number index (MUNIX), and motor unit size index (MUSIX) were then calculated for each muscle. There was a significant AI reduction for all the three muscles in paretic side compared with...
Source: IEEE Transactions on Biomedical Engineering - December 1, 2014 Category: Biomedical Engineering Source Type: research