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Nutrition: Potassium

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The KATP channel opener, nicorandil, ameliorates brain damage by modulating synaptogenesis after ischemic stroke
by Yuanzheng Zhao, Zhuoying Yang, Yuanhong He, Ruonan Sun, Heping Yuan With population growth and aging, more and more patients with cerebral infarction have varying degrees of disability. ATP-sensitive potassium (KATP) channels regulate many cellular functions by coupling metabolic status with cell membrane electrical activity. Nicorandil (N-(2-hydroxyethyl)-nicotin amide nitrate) is the first KATP channel opener approved for clinical use. It has been reported that it might exert protective effects on the cerebral infarction by increasing cerebral blood flow and reducing inflammation. However, only a few studies explored...
Source: PLoS One - January 26, 2021 Category: Biomedical Science Authors: Yuanzheng Zhao Source Type: research