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Specialty: Genetics & Stem Cells
Source: Genomics Data
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Stroke-associated pattern of gene expression previously identified by machine-learning is diagnostically robust in an independent patient population
The objective of this study was to assess the diagnostic capacity and temporal stability of this stroke-associated transcriptional signature in an independent patient population. Publicly available whole blood microarray data generated from 23 ischemic stroke patients at 3, 5, and 24h post-symptom onset, as well from 23 cardiovascular disease controls, were obtained via the National Center for Biotechnology Information Gene Expression Omnibus. Expression levels of the ten candidate genes (ANTXR2, STK3, PDK4, CD163, MAL, GRAP, ID3, CTSZ, KIF1B, and PLXDC2) were extracted, compared between groups, and evaluated for their dis...
Source: Genomics Data - September 2, 2017 Category: Genetics & Stem Cells Source Type: research
