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The unsolved role of heightened connectivity from the unaffected hemisphere to paretic arm muscles in chronic stroke.
CONCLUSIONS: Despite enhanced ipsilateral connectivity, arm function and learning was related most strongly to contralateral pathway integrity from the stroke hemisphere. SIGNIFICANCE: Further work is needed to decipher the role of ipsilateral connections. PMID: 30925310 [PubMed - as supplied by publisher]
Source: Clinical Neurophysiology - March 17, 2019 Category: Neurology Authors: Hammerbeck U, Hoad D, Greenwood R, Rothwell JC Tags: Clin Neurophysiol Source Type: research

Endpoint accuracy of goal-directed ankle movements correlates to over-ground walking in stroke.
CONCLUSIONS: Impaired accuracy of goal-directed, ankle movements is correlated to over-ground walking in stroke. SIGNIFICANCE: Quantifying accuracy of goal-directed ankle movements may provide insights into walking function post-stroke. PMID: 31005051 [PubMed - as supplied by publisher]
Source: Clinical Neurophysiology - April 12, 2019 Category: Neurology Authors: Lodha N, Patel P, Casamento-Moran A, Gauger K, Christou EA Tags: Clin Neurophysiol Source Type: research

Behavioral and neurophysiological mechanisms underlying motor skill learning in patients with post-stroke hemiparesis.
CONCLUSIONS: When execution deficits are accounted for, patients with stroke demonstrate relatively intact motor skill learning with the paretic arm. Paretic arm learning is accompanied by modulations in corticospinal and transcallosal mechanisms. SIGNIFICANCE: Functional recovery after stroke relies on ability for skill learning and the underlying mechanisms. PMID: 29127826 [PubMed - as supplied by publisher]
Source: Clinical Neurophysiology - November 8, 2017 Category: Neurology Authors: Kantak S, McGrath R, Zahedi N, Luchmee D Tags: Clin Neurophysiol Source Type: research

The effect of transcranial direct current stimulation on motor sequence learning and upper limb function after stroke.
CONCLUSIONS: Unilateral tDCS is effective for improving JTT performance, but not motor sequence learning. SIGNIFICANCE: This has implications for the design of future clinical trials. PMID: 28410884 [PubMed - as supplied by publisher]
Source: Clinical Neurophysiology - March 31, 2017 Category: Neurology Authors: Fleming MK, Rothwell JC, Sztriha L, Teo JT, Newham DJ Tags: Clin Neurophysiol Source Type: research

Neurofeedback training of alpha-band coherence enhances motor performance.
CONCLUSIONS: These results provide proof of concept that neurofeedback training of alpha-band coherence is feasible and behaviorally useful. SIGNIFICANCE: The study presents evidence for a role of alpha-band coherence in motor learning and may lead to new strategies for rehabilitation. PMID: 25540133 [PubMed - as supplied by publisher]
Source: Clinical Neurophysiology - December 6, 2014 Category: Neurology Authors: Mottaz A, Solcà M, Magnin C, Corbet T, Schnider A, Guggisberg AG Tags: Clin Neurophysiol Source Type: research