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Brain stimulation and constraint for perinatal stroke hemiparesis: The PLASTIC CHAMPS Trial
Conclusions: Hemiparetic children participating in intensive, psychosocial rehabilitation programs can achieve sustained functional gains. Addition of CIMT and rTMS increases the chances of improvement. Classification of evidence: This study provides Class II evidence that combined rTMS and CIMT enhance therapy-induced functional motor gains in children with stroke-induced hemiparetic cerebral palsy.
Source: Neurology - May 1, 2016 Category: Neurology Authors: Kirton, A., Andersen, J., Herrero, M., Nettel-Aguirre, A., Carsolio, L., Damji, O., Keess, J., Mineyko, A., Hodge, J., Hill, M. D. Tags: All Rehabilitation, Plasticity, TMS, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke ARTICLE Source Type: research

Transcranial direct current stimulation for children with perinatal stroke and hemiparesis
Conclusion: tDCS trials appear feasible and safe in hemiparetic children. Lack of change in objective motor function may reflect underdosing of therapy. Marked gains in subjective function with tDCS warrant further study. ClinicalTrials.gov identifier: NCT02170285. Classification of evidence: This study provides Class II evidence that for children with perinatal stroke and hemiparetic cerebral palsy, the addition of tDCS to moderate-dose motor learning therapy does not significantly improve motor function as measured by the AHA.
Source: Neurology - January 15, 2017 Category: Neurology Authors: Kirton, A., Ciechanski, P., Zewdie, E., Andersen, J., Nettel-Aguirre, A., Carlson, H., Carsolio, L., Herrero, M., Quigley, J., Mineyko, A., Hodge, J., Hill, M. Tags: Childhood stroke, Clinical trials Randomized controlled (CONSORT agreement), All Rehabilitation, Plasticity, TMS ARTICLE Source Type: research