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Condition: Pulmonary Thromboembolism
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Total 42 results found since Jan 2013.

Can Patent Foramen Ovales Cause Problems?
Discussion During fetal development, the heart primum and secundum septa grow and overlap leaving a small but important channel between the two atria. The foramen ovale is a flap valve moving blood from the right atrium into the left atrium directly and bypassing the high pressure pulmonary system. After birth and breathing air, the neonate’s lungs open up and the pulmonary vascular resistance decreases. The left atrium now has a relatively higher pressure than the right atria, and therefore pressure on the flap valve closes the foramen ovale. Usually within 6-12 months, the fusion of the primum and secundum of the f...
Source: PediatricEducation.org - July 24, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Prediction of incident atrial fibrillation in community-based electronic health records: a systematic review with meta-analysis
Conclusions Models externally validated for prediction of incident AF in community-based EHR demonstrate moderate predictive ability and high risk of bias. Novel methods may provide stronger discriminative performance. Systematic review registration PROSPERO CRD42021245093.
Source: Heart - June 10, 2022 Category: Cardiology Authors: Nadarajah, R., Alsaeed, E., Hurdus, B., Aktaa, S., Hogg, D., Bates, M. G. D., Cowan, C., Wu, J., Gale, C. P. Tags: Open access Arrhythmias and sudden death Source Type: research

337-i * thoracoscopic left atrial appendectomy
Conclusions: This approach demonstrated feasibility, safety and effectiveness and should be considered as a possible alternative to percutaneous closure of the LAA. However, its effect on long-term prevention of stroke needs to be evaluated.
Source: Interactive CardioVascular and Thoracic Surgery - September 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Guerra, M., Miranda, J., Martins, D., Neves, P., Gama, V., Vouga, L. Tags: Learning from experience (film) Source Type: research

Preventable Cases of Oral Anticoagulant-Induced Bleeding: Data From the Spontaneous Reporting System
Conclusion: Our findings describe the most reported risk factors for preventability of oral anticoagulant-induced bleedings. These factors may be useful for targeting interventions to improve pharmacovigilance activities in our regional territory and to reduce the burden of medication errors and inappropriate prescription. Introduction Oral anticoagulant therapy is widely used for the prevention of stroke and systemic embolism in patients with atrial fibrillation, or for the prevention and treatment of deep vein thrombosis and pulmonary embolism (Raj et al., 1994; Monaco et al., 2017). Oral anticoagulants can be di...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research

Late-Breaking Phase 2 Data for Investigational Oral Factor XIa Inhibitor Milvexian Suggest Favorable Antithrombotic Profile Across a Wide Range of Doses
This study establishes proof-of-principle for milvexian as a differentiated antithrombotic agent,” said Jeffrey Weitz, M.D., Professor of Medicine & Biochemistry and Biomedical Sciences at McMaster University and Executive Director of the Thrombosis and Atherosclerosis Research Institute.[i] “Furthermore, the consistently low rates of bleeding across a 16-fold range of milvexian doses suggest that it has a wide therapeutic window, which opens the opportunity to explore milvexian across a broad range of patients including those for whom factor Xa inhibitors are underutilized or not indicated.” The trial met both o...
Source: Johnson and Johnson - November 15, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Yaz Settlement News Provided by the Skikos Law Firm, New Claims Still...
Yaz lawsuits continue to result in settlements for victims of blood clots and related injuries such as stroke, deep vein thrombosis (DVT), and pulmonary embolism (PE). Readers can learn more at...(PRWeb May 08, 2013)Read the full story at http://www.prweb.com/releases/2013/5/prweb10707101.htm
Source: PRWeb: Medical Pharmaceuticals - May 11, 2013 Category: Pharmaceuticals Source Type: news

157 E-Books New to JEFFLINE
Scott Library added these 157 e-books to the growing collection in May and June: Accurate Results in the Clinical Laboratory Adult Emergency Medicine Adult-Gerontology and Family Nurse Practitioner Certification Examination (4th ed.) Advanced Assessment: Interpreting Findings and Formulating Differential Diagnoses (2nd ed.) Advancing Your Career: Concepts of Professional Nursing (5th ed.) Arrhythmia Essentials Atlas of Advanced Operative Surgery Atlas of Clinical Neurology (3rd ed.) Atlas of Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches Atlas of Human Infectious Diseases Atlas of No...
Source: What's New on JEFFLINE - June 25, 2013 Category: Databases & Libraries Authors: Gary Kaplan Tags: All News Clinicians Researchers Students Teaching Faculty Source Type: news

Yaz Settlements Reach $1.4 Billion Reports the Skikos Law Firm, New...
Women who allegedly suffered blood clot injuries such as stroke, pulmonary embolism (PE), and deep vein thrombosis (DVT) continue to receive Yaz lawsuit settlements in 2013. Readers can learn more at...(PRWeb July 31, 2013)Read the full story at http://www.prweb.com/releases/2013/7/prweb10982921.htm
Source: PRWeb: Medical Pharmaceuticals - July 31, 2013 Category: Pharmaceuticals Source Type: news

NuvaRing Lawsuit and Settlement Update from the Skikos Firm, New...
A growing number of NuvaRing users have filed lawsuits alleging blood clots and related side effects such as stroke, pulmonary embolism, and DVT. Readers can learn more at...(PRWeb January 15, 2014)Read the full story at http://www.prweb.com/releases/2014/01/prweb11482791.htm
Source: PRWeb: Medical Pharmaceuticals - January 15, 2014 Category: Pharmaceuticals Source Type: news

A Hidden Danger In The New Versions Of Birth Control Pills
Women who take a newer version of birth control pills have a doubled risk of developing potentially fatal blood clots, according to a new study published in the British medical journal BMJ. Venous thromboembolism is a serious condition that encompasses both deep vein thrombosis -- when a person develops a blood clot in the legs -- and pulmonary embolism, in which the clot travels to the lungs and obstructs breathing. VTE is potentially fatal, and the study indicates that women who take combined oral contraceptives with newer progesterone formulations are two times more likely to develop it as opposed to women who take a ...
Source: Science - The Huffington Post - May 27, 2015 Category: Science Source Type: news

Long-standing persistent effects of atrial volume reduction combined with pulmonary vein isolation
Publication date: Available online 18 June 2018 Source:Journal of Cardiology Cases Author(s): Masami Takagaki, Naoko Ikeda, Hiroki Yamaguchi, Shinichi Mitsuyama, Tasuku Kadowaki, Tatsuya Nakao Although surgical left atrial (LA) volume reduction combined with mitral valve surgery and/or surgical ablation for atrial fibrillation has been reported to be effective, its long-term outcomes in the absence of mitral procedure are not well established. A 74-year-old man with two previous sternotomies—the first for pericardiectomy due to constrictive pericarditis and the second for mitral valve replacement with mechanical valve a...
Source: Journal of Cardiology Cases - June 20, 2018 Category: Cardiology Source Type: research

Paradoxical embolism caused by ovarian vein thrombosis extending to inferior vena cava in a female with uterine myoma
We report the case of a 42-year-old female who was hospitalized for stroke. Detailed investigations revealed the existence of a PFO, pulmonary embolism, and ovarian vein thrombosis extending to inferior vena cava. She had a uterine myoma to be operated on but no other thrombophilic disorders. Anticoagulation therapy with direct oral anticoagulant successfully reduced the thrombus and prevented the recurrence of paradoxical embolism.<Learning objective: Ovarian vein thrombosis (OVT) is often associated with malignancy, pelvic surgery, or pregnancy. This case shows uterine myoma as a possible cause of OVT and demonstrate...
Source: Journal of Cardiology Cases - September 5, 2018 Category: Cardiology Source Type: research

Pulmonary embolism with migrating thrombus through patent foramen ovale: A case for a mixed pharmacological and percutaneous management
Publication date: Available online 27 September 2018Source: Journal of Cardiology CasesAuthor(s): Gloria Santangelo, Alfonso Ielasi, Francesco Pattarino, Antonio Tommaso Saino, Pasquale Antonio Scopelliti, Maurizio TespiliAbstractA 61-year-old man, admitted to our hospital for bilateral pulmonary embolism, complicated by right renal ischemia and multiple splenic infarcts due to a mobile thrombus entrapped in a patent foramen ovale, has been successfully treated with apixaban 5 mg twice daily followed by transcatheter patent foramen ovale closure.<Learning objective: Apixaban could be a therapeutic alternative to t...
Source: Journal of Cardiology Cases - October 4, 2018 Category: Cardiology Source Type: research