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Source: NIH OTT Licensing Opportunities
Condition: Huntington's Disease
Education: Learning
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Derivatives of Docosahexaenoylethanolamide (DEA) for Neurogenesis
The invention pertains to derivatives of docosahexaenoylethanolamide (synaptamide or DEA) and their use in inducing neurogenesis, neurite growth, and/or synaptogenesis. As such, these DEA derivatives can be used as therapeutics for neurodegenerative diseases such as traumatic brain injury, spinal cord injury, peripheral nerve injury, stroke, multiple sclerosis, autism, Alzheimer ' s disease, Huntington ' s disease, Parkinson ' s disease, amyotrophic lateral sclerosis. The DEA derivatives of the invention have increased potency and hydrolysis resistance as compared to native DEA. Docosahexaenoic acid (DHA), an n-3 polyunsat...
Source: NIH OTT Licensing Opportunities - January 24, 2013 Category: Research Authors: ajoyprabhu3 Source Type: research
