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Source: Acta Neurologica Taiwanica
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Total 540 results found since Jan 2013.

Intravenous Alteplase for Acute Ischemic Stroke in Taiwan: Can We Expand the National Health Insurance's Reimbursement Criteria?
In conclusion, the non-reimbursement group in Su, et al(3). is a mixture of stroke patients with very heterogeneous characteristics. With the advances of imaging selection modalities and new hyperacute treatment options nowadays, they should no longer be considered as an identical group of patients. We strokologists, as an emerging subspecialists, should devote more in dedicated and individualized selection of stroke patients for appropriate early recanalization therapy to improve their outcomes. Conflict of Interest Disclosure: I received speaker fee from Boehringer Ingelheim for Actilyse® (http://grsp2013.innovarad.tw/2...
Source: Acta Neurologica Taiwanica - July 30, 2017 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Malnutrition in Acute Stroke Patients Stratified by Stroke Severity- A Hospital Based Study.
CONCLUSION: Nutritional status was poor in stroke patients across all stroke severities within weeks. Further longitudinal outcome studies to identify the poor outcome and the evolution of nutritional status are warranted. PMID: 29468620 [PubMed - in process]
Source: Acta Neurologica Taiwanica - February 24, 2018 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Parkinsonism or Other Movement Disorders Presenting as Stroke Mimics.
CONCLUSION: Although rare, parkinsonism or other movement disorders may present as a stroke mimic with activation of a stroke code. Consulting neurologists should clarify the etiology for those patients with acute consciousness disturbance or motor weakness and avoid unnecessary thrombolysis. Key Words: Parkinson disease, parkinsonism, movement disorders, stroke code, thrombolysis. PMID: 28382611 [PubMed - in process]
Source: Acta Neurologica Taiwanica - April 8, 2017 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Urgent Demand of Network Access for Acute Ischemic Stroke Management in Taiwan
Acta Neurol Taiwan. 2022 Sep 30;31(3):84-90.ABSTRACTTime is the major determinant in successful reperfusion therapy of acute ischemic stroke. The evolving diagnostic tools and treatment of acute stroke has made a great progress in the past 2 decades and is remolding current management practices. It demands a timely neurologic evaluation and a neuroimaging study to determine if stroke patients are appropriate candidates for reperfusion demands. Therefore, it is critical for the setting of stroke center accreditation levels and capabilities so that timely and appropriate treatment is initiated for the eligible stroke patient...
Source: Acta Neurologica Taiwanica - April 19, 2022 Category: Neurology Authors: Jiu-Haw Yin Hung-Yi Wu Chun Chien Li-Chi Hsu Jiunn-Tay Lee Han-Hwa Hu Giia-Sheun Peng Source Type: research

Development of an educational program for staffs of emergency medical service to improve their awareness of stroke within 3 hours of symptom onset: a pilot study.
CONCLUSION: The educational program increased knowledge about stroke and improved the accuracy of triage by dedicated EMS providers. Further investigation is needed to determine the effectiveness of similar educational programs for non-dedicated EMS responders. PMID: 23479240 [PubMed - indexed for MEDLINE]
Source: Acta Neurologica Taiwanica - December 12, 2015 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

BNG-1 in the Recovery of Acute Ischemic Stroke: A phase 2, Double-blind, Placebo-controlled Randomized Trial.
CONCLUSIONS: BNG-1 trial was feasible, safe and well tolerated for patients with acute ischemic stroke based on the treatment of aspirin, though there was no statistically significant difference of efficacy between BNG-1 and placebo groups. A further large Phase 3 trial of BNG-1 is needed before recommending such treatments for general clinical use. PMID: 27333830 [PubMed - in process]
Source: Acta Neurologica Taiwanica - June 25, 2016 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Quality of Life and Psychological Distress of Caregivers' of Stroke People.
CONCLUSIONS: Caregivers of people with stroke experience mental disorders and burden negatively affecting their quality of life. Therefore, there is a need to implement strategies which should aim to the management of these problems for the welfare of both patients and their caregivers. PMID: 30315561 [PubMed - in process]
Source: Acta Neurologica Taiwanica - October 15, 2018 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Renal Function Estimates and Dosing of Direct Oral Anticoagulants in Stroke Patients with Atrial Fibrillation: An Observational Study.
CONCLUSION: Although substituting eGFR for CrCl carries potential risks of DOAC overdosing in patients with AF, the effect might be offset by clinicians' predilection for lower dosage in this stroke cohort. PMID: 31304571 [PubMed - in process]
Source: Acta Neurologica Taiwanica - July 17, 2019 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Significant Destructive Interaction of BDNF Val > Met Polymorphism with Stroke Severity and Family History of Dementia for Cognitive Impairments.
CONCLUSION: It can be speculated that presence of Val/Met heterozygosity has a destructive interaction with the SS and FHD for decreasing the cognitive function, particularly in attention and language domains. Our findings suggested that the inhibition of signaling and trafficking of Val/Met heterozygosity is possibly a practical strategy in reducing the cognitive impairments following the stroke. PMID: 32996114 [PubMed - in process]
Source: Acta Neurologica Taiwanica - October 2, 2020 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Update of Intravenous Thrombolytic Therapy in Acute Ischemic Stroke
Acta Neurol Taiwan. 2021 Jun 30;30(2):44-53.ABSTRACTUpon acute ischemic stroke, rapid recanalization of the occluded cerebral vessel via intravenous thrombolytic therapy (IVT) is crucial to achieve good functional outcome. The time window of IVT with recombinant tissue plasminogen activator (rt-PA) has been extended from post-stroke 3 to 4.5 hours. In patients with cerebral penumbra identified using cerebral perfusion imaging, IVT is still beneficial within 4.5 to 9 hours after onset of stroke. For those without clear stroke onset time, DWI-FLAIR mismatch by brain MRI indicates hyperacute infarct and IVT is indicative. For...
Source: Acta Neurologica Taiwanica - September 22, 2021 Category: Neurology Authors: Li-Kai Tsai Jiann-Shing Jeng Source Type: research