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Transferring neurointerventionalists saves time compared with interhospital transfer of stroke patients for endovascular thrombectomy: a collaborative pooled analysis of 1001 patients (EVEREST)
Conclusions This pooled analysis of the EVEREST collaboration adds evidence that performing EVT at external hospitals can save time compared with drip and ship across various geographical regions. We encourage conducting randomized controlled trials comparing both triage concepts.
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Seker, F., Fifi, J. T., Morey, J. R., Osanai, T., Oki, S., Brekenfeld, C., Fiehler, J., Bendszus, M., Möhlenbruch, M. A. Tags: Open access, Ischemic stroke Source Type: research

Travel time and distance for bypass and non-bypass routing of stroke patients in the USA
Conclusions Bypass routing offers modest travel time benefits for LVO patients and incurs modest penalties for non-LVO patients. Differences are greatest in rural areas. A majority of Americans live in areas for which current guidelines recommend bypass.
Source: Journal of NeuroInterventional Surgery - June 16, 2023 Category: Neurosurgery Authors: Yu, C. Y., Panagos, P. D., Kansagra, A. P. Tags: Ischemic stroke Source Type: research

Admission neutrophil-lymphocyte ratio predicts 90 day outcome after endovascular stroke therapy
Conclusions This study shows that the NLR, a readily available biomarker, may be a clinically useful tool for risk stratification when evaluating AIS patients as candidates for endovascular therapies.
Source: Journal of NeuroInterventional Surgery - September 5, 2014 Category: Neurosurgery Authors: Brooks, S. D., Spears, C., Cummings, C., VanGilder, R. L., Stinehart, K. R., Gutmann, L., Domico, J., Culp, S., Carpenter, J., Rai, A., Barr, T. L. Tags: Editor''s choice, Ischemic stroke Source Type: research

Direct carotid artery puncture access for endovascular treatment of acute ischemic stroke: technical aspects, advantages, and limitations
Conclusions Direct carotid artery puncture is a feasible alternative to transfemoral artery access in cases of stroke with difficult anatomy, including unfavorable arch type, carotid tortuosity, or an ostial lesion.
Source: Journal of NeuroInterventional Surgery - January 13, 2015 Category: Neurosurgery Authors: Mokin, M., Snyder, K. V., Levy, E. I., Hopkins, L. N., Siddiqui, A. H. Tags: Ischemic stroke Source Type: research

Correlation between cerebral blood volume values and outcomes in endovascular therapy for acute ischemic stroke
Conclusions We found that cortical CBV loss is predictive of poor clinical outcomes, whereas basal ganglia CBV loss is predictive of hemorrhagic transformation but without translation into poor clinical outcomes. Our study findings support published results of baseline preintervention CBV as a predictor of outcomes in patients undergoing intra-arterial stroke therapies.
Source: Journal of NeuroInterventional Surgery - September 13, 2015 Category: Neurosurgery Authors: Mokin, M., Morr, S., Fanous, A. A., Shallwani, H., Natarajan, S. K., Levy, E. I., Snyder, K. V., Siddiqui, A. H. Tags: Ischemic stroke Source Type: research

Trends in mortality following mechanical thrombectomy for the treatment of acute ischemic stroke in the USA
Conclusions Utilization of MT represents a small percentage of stroke cases, although the trend is increasing. Mortality following MT has been showing a steady decline over the past 5 years. This may be a result of a learning curve, improved patient selection, and/or device improvements. Randomized trials remain essential to evaluate the potential benefit of endovascular devices and identify the most appropriate patients.
Source: Journal of NeuroInterventional Surgery - April 13, 2016 Category: Neurosurgery Authors: Villwock, M. R., Padalino, D. J., Deshaies, E. M. Tags: Ischemic stroke Source Type: research

Hemodynamics during anesthesia for intra-arterial therapy of acute ischemic stroke
Conclusions Patients with acute ischemic stroke undergoing intra-arterial therapy with general anesthesia had lower minimum SBP, DBP, and MAP, greater fluctuations in blood pressure, and less favorable outcomes. More studies are needed to examine the implications of variable and reduced blood pressures and neurological outcomes.
Source: Journal of NeuroInterventional Surgery - August 11, 2016 Category: Neurosurgery Authors: Jagani, M., Brinjikji, W., Rabinstein, A. A., Pasternak, J. J., Kallmes, D. F. Tags: Ischemic stroke Source Type: research

Stroke vision, aphasia, neglect (VAN) assessment--a novel emergent large vessel occlusion screening tool: pilot study and comparison with current clinical severity indices
Conclusions The VAN screening tool accurately identified ELVO patients and outperformed a NIHSS ≥6 severity threshold and may best allow clinical teams to expedite care and mobilize resources for ELVO patients. A larger study to both validate this screening tool and compare with others is warranted.
Source: Journal of NeuroInterventional Surgery - January 12, 2017 Category: Neurosurgery Authors: Teleb, M. S., Ver Hage, A., Carter, J., Jayaraman, M. V., McTaggart, R. A. Tags: Open access, Ischemic stroke Source Type: research

Predictors of false-positive stroke thrombectomy transfers
Conclusions Clinical scales appear to overdiagnose LVO and may be responsible for the majority of our stroke code transfers not undergoing thrombectomy. Primary stroke centres therefore have reason to develop the capability to rapidly acquire and interpret a CTA in patients with suspected LVO prior to transfer. Such efforts may reduce the costs associated with unnecessary thrombectomy transfers.
Source: Journal of NeuroInterventional Surgery - August 17, 2017 Category: Neurosurgery Authors: Yi, J., Zielinski, D., Ouyang, B., Conners, J., Dafer, R., Chen, M. Tags: Editor''s choice, Ischemic stroke Source Type: research

Ultra-distal access of the M1 segment with the 5 Fr Navien distal access catheter in acute (anterior circulation) stroke: is it safe and efficient?
Conclusions Ultra-distal placement of the Navien 58 distal access catheter into the M1 segment in acute anterior circulation stroke can be achieved consistently, is safe in practice, and results in good recanalization success rates.
Source: Journal of NeuroInterventional Surgery - June 16, 2017 Category: Neurosurgery Authors: Janssen, H., Killer-Oberpfalzer, M., Patzig, M., Buchholz, G., Lutz, J. Tags: Ischemic stroke Source Type: research

In-thrombus thrombin secretion: a new diagnostic marker of atrial fibrillation in cryptogenic stroke
Conclusions An assay measuring the change in thrombin in clots retrieved during acute stroke endovascular thrombectomy procedures may serve as a diagnostic marker of the origin of the clot. The suggested mechanism for these differences may be the clot location before its retrieval, with high blood flow causing thrombin washout in atherosclerotic clots, in contrast to atrium appendage low blood flow retaining high thrombin levels.
Source: Journal of NeuroInterventional Surgery - August 13, 2021 Category: Neurosurgery Authors: Itsekson Hayosh, Z., Abu Bandora, E., Shelestovich, N., Nulman, M., Bakon, M., Yaniv, G., Khaitovitch, B., Balan, S., Gerasimova, A., Drori, T., Mausbach, S., Schwammenthal, Y., Afek, A., Chapman, J., Shavit Stein, E., Orion, D. Tags: Ischemic stroke Source Type: research

Is a picture-perfect thrombectomy necessary in acute ischemic stroke?
Conclusions Complete and near-complete reperfusion after MT appear to confer comparable outcomes in patients with acute stroke.
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Chen, C.-J., Chalhoub, R., Ding, D., Kumar, J. S., Ironside, N., Kellogg, R. T., Worrall, B. B., Southerland, A. M., Jabbour, P., Wolfe, S. Q., Arthur, A. S., Goyal, N., Fragata, I., Maier, I., Matouk, C., Grossberg, J. A., Kan, P., Schirmer, C. M., Crowl Tags: Editor''s choice, Ischemic stroke Source Type: research

Mapping access to endovascular stroke care in the USA and implications for transport models
Conclusion Nearly one-third of the US population lacks 60 min access to endovascular stroke care, but this is highly variable. Transport models and planning of additional centers should be tailored to each state depending on location and proximity of existing facilities.
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Aldstadt, J., Waqas, M., Yasumiishi, M., Mokin, M., Tutino, V. M., Rai, H. H., Chin, F., Levy, B. R., Rai, A. T., Mocco, J., Snyder, K. V., Davies, J. M., Levy, E. I., Siddiqui, A. H. Tags: Ischemic stroke Source Type: research

Rates of adverse events in patients with ischemic stroke treated at thrombectomy capable hospitals
Conclusions A decrease in-hospital adverse events and improved discharge outcomes were observed among patients with ischemic stroke admitted to a TCH compared with a non-TCH.
Source: Journal of NeuroInterventional Surgery - March 18, 2022 Category: Neurosurgery Authors: Chaudhry, S. A., Sadaf, H., Laleka, I., Nasir, W., Witzel, C., Bahiru, Z., Fang, Y., Ishfaq, F., Altaweel, L. R., Qureshi, A. I. Tags: Ischemic stroke Source Type: research

Analysis of microRNA signatures in ischemic stroke thrombus
Conclusions The microRNA expression pattern can provide information regarding the mechanism of stroke by reflecting the underlying pathological status of the organ from which the thrombus was derived.
Source: Journal of NeuroInterventional Surgery - April 12, 2022 Category: Neurosurgery Authors: Kim, J.-M., Byun, J.-S., Kim, J., Park, M.-S., Hong, S. A., Nam, T.-K., Choi, H. H., Hong, S., Han, S.-H., Jeong, H.-B., Park, K.-Y., Kim, H. R. Tags: Ischemic stroke Source Type: research

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