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Source: Heart Rhythm
Condition: Atrial Fibrillation
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Total 356 results found since Jan 2013.
Relationship between left atrial appendage morphology and stroke in patients with atrial fibrillation
Background: Atrial fibrillation (AF) is an important cause of stroke. Given the morbidity and mortality associated with stroke, the risk stratification of patients based on left atrial appendage (LAA) characteristics is of great interest.Objective: To explore the association between LAA morphology and LAA characteristics including the extent of trabeculations, orifice diameter, and length with prevalent stroke in a large cohort of patients with drug refractory AF who underwent AF ablation to develop mechanistic insight regarding the risk of stroke.Methods: An institutional cohort of 1063 patients referred for AF ablation f...
Source: Heart Rhythm - September 27, 2013 Category: Cardiology Authors: Irfan M. Khurram, Jane Dewire, Michael Mager, Farhan Maqbool, Stefan L. Zimmerman, Vadim Zipunnikov, Roy Beinart, Joseph E. Marine, David D. Spragg, Ronald D. Berger, Hiroshi Ashikaga, Saman Nazarian, Hugh Calkins Tags: Atrial Fibrillation Source Type: research
Atrial fibrillation ablation patients have long-term stroke rates similar to patients without atrial fibrillation regardless of CHADS2 score
Background: Atrial fibrillation (AF) is a leading cause of total and fatal ischemic stroke. Stroke risk after AF ablation appears to be favorably affected; however, it is largely unknown whether the benefit extends to all stroke CHADS2 risk profiles of AF patients.Objective: To determine if ablation of atrial fibrillation reduces stroke rates in all risk groups.Methods: A total of 4212 consecutive patients who underwent AF ablation were compared (1:4) with 16,848 age-/sex-matched controls with AF (no ablation) and to 16,848 age-/sex-matched controls without AF. Patients were enrolled from the large ongoing prospective Inte...
Source: Heart Rhythm - July 8, 2013 Category: Cardiology Authors: T. Jared Bunch, Heidi T. May, Tami L. Bair, J. Peter Weiss, Brian G. Crandall, Jeffrey S. Osborn, Charles Mallender, Jeffrey L. Anderson, Brent J. Muhlestein, Donald L. Lappe, John D. Day Tags: Ablation Source Type: research
Stroke prevention in atrial fibrillation—An Asian stroke perspective
Despite relatively lower prevalence of atrial fibrillation (AF) in Asians (~1%) than in Caucasians (~2%), Asia has a much higher overall disease burden because of its proportionally larger aged population. For example, on the basis of reported age-adjusted prevalence rates and projected population figures in China, there will be an estimated 5.2 million men and 3.1 million women with AF older than 60 years by year 2050. Stroke is a disabling complication of AF that is of increasing cause for concern in Asians patients. Implementing consensus expert recommendations for managing stroke risk in patients with AF can considerab...
Source: Heart Rhythm - March 18, 2013 Category: Cardiology Authors: Hung-Fat Tse, Yong- Jun Wang, Moheeb Ahmed Ai-Abdullah, Annette B. Pizarro-Borromeo, Chern-En Chiang, Rungroj Krittayaphong, Balbir Singh, Amit Vora, Chun-Xue Wang, Mohammad Zubaid, Andreas Clemens, Paul Lim, Dayi Hu Tags: Contemporary Review--Associate Editor: Sami Viskin Source Type: research
Anatomical characteristics of the left atrial appendage in cardiogenic stroke with low CHADS2 scores
Conclusions: The LAA anatomy might be useful for predicting strokes in patients with nonvalvular AF who have low CHADS2 scores.
Source: Heart Rhythm - February 4, 2013 Category: Cardiology Authors: Takehiro Kimura, Seiji Takatsuki, Kohei Inagawa, Yoshinori Katsumata, Takahiko Nishiyama, Nobuhiro Nishiyama, Kotaro Fukumoto, Yoshiyasu Aizawa, Yoko Tanimoto, Kojiro Tanimoto, Masahiro Jinzaki, Keiichi Fukuda Tags: Creative Concepts Source Type: research
Author's reply to Atrial fibrillation patients with hypertrophic cardiomyopathy: Do we need new stroke risk stratification?
We thank Dr. Joung and colleagues for their interests in our work.1 In our study, patients with non-valvular atrial fibrillation (NVAF) with hypertrophic cardiomyopathy (HCM) had a higher risk of stroke than NVAF patients without HCM in all generations and all CHA2DS2-VASc score groups. As shown in the study of Jung et al.,2 the stroke risk in NVAF with HCM without any other stroke risk factor was greater than that in NVAF with a CHA2DS2-VASc score of 2. We agree with their results, and all NVAF patients with HCM should receive anticoagulation.
Source: Heart Rhythm - April 3, 2019 Category: Cardiology Authors: Toyonobu Tsuda, Akihiro Nomura, Kenshi Hayashi Source Type: research
Reply to the Editor — Patients with atrial fibrillation with hypertrophic cardiomyopathy: Do we need new stroke risk stratification?
We thank Joung et al for their interest in our work.1 In our study, patients with nonvalvular atrial fibrillation (NVAF) with hypertrophic cardiomyopathy (HCM) had a higher risk of stroke than did patients with NVAF without HCM in all generations and all CHA2DS2-VASc score groups. As shown in the study by Jung et al,2 stroke risk in patients with NVAF with HCM without any other stroke risk factor was higher than that in patients with NVAF with a CHA2DS2-VASc score of 2. We agree with their results, and all patients with NVAF with HCM should receive anticoagulation.
Source: Heart Rhythm - April 3, 2019 Category: Cardiology Authors: Toyonobu Tsuda, Akihiro Nomura, Kenshi Hayashi Source Type: research
Ce-543-01 4-fold higher rate of atrial fibrillation detection after stroke of presumed known etiology with continuous versus intermittent monitoring: results from the stroke af study
In patients (pts) with recent ischemic stroke, atrial fibrillation (AF) may be common regardless of the stroke etiology. Timely diagnosis and intervention may prevent more disabling recurrent strokes.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Jonathan P. Piccini, Christopher Granger, Richard A. Bernstein, Hooman Kamel, Jeffrey Katz, pramod P. sethi, Evgeny Sidorov, Scott E. Kasner, Scott B. Silverman, Theodore Merriam, Paul Ziegler, Lee Schwamm Source Type: research
Po-693-03 atrial fibrillation in cryptogenic stroke: a real-world study with insertable cardiac monitor
Patients with cryptogenic stroke (CS) undergo insertable cardiac monitor (ICM) screen for occult atrial fibrillation (AF) as a possible ischemic stroke etiology. Continuous monitoring with ICM was shown to be superior to intermittent cardiac monitoring in the detection of AF in the CRYSTAL-AF Trial. However, there is limited real-world data about the rate of AF detection using ICM in patients with cryptogenic stroke.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Payam Safavi-Naeini, Erica Kim, Joanna E. Molina Razavi, Mohammad Saeed, Abdi Rasekh, Mehdi Razavi, Mihail G. Chelu Source Type: research
Po-670-06 efficacy and safety of left atrial appendage occlusion during cardiac surgery to prevent stroke: a systematic review and meta-analysis
Stroke remains one of the significant causes of morbidity and mortality after cardiac surgery. One stroke occurrence is postoperative atrial fibrillation (pAF), with an incidence ranging between 20% and 40%. PAF predisposes to the formation of atrial thrombus. Most thrombus formations observed in the left atrial appendage (LAA) have triggered significant interest as a potential therapeutic target. Current guidelines recommend the administration of direct oral anticoagulants (DOACs) as the preferred therapy to prevent stroke in patients with atrial fibrillation with a CHA2DS2-VASc of ≥ 2.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Reynald Evan Tugade, Billy Joseph David, Clara Sy Tolentino Source Type: research
Ce-452778-1 left atrial mechanical dysfunction and the incidence of atrial fibrillation within 1 year of embolic stroke of unknown source
Atrial fibrillation (AF) is detected in a significant proportion of patients with embolic stroke of unkown source (ESUS) on subsequent cardiac monitoring and represents an indication for anticoagulation to prevent future stroke in these patients. Left atrial mechanical dysfunction often precedes development of atrial fibrillation and may represent an upstream marker which can readily be assessed at the point of care to inform decisions about future stroke prevention in people with ESUS.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Ravi S. Shah, Joseph Raco, Ryan Williams, Michael Farbaniec, Nathaniel D. McConkey, Kevin J. Mills, ankit maheshwari Source Type: research
Ci-452768-1 impact of new-onset atrial fibrillation detected by cardiac implantable electronic devices on cardioembolic stroke events
The association between atrial fibrillation (AF) detected by implanted cardiac implantable electronic devices (CIEDs) and the incidence of cardioembolic stroke events has been reported. However, the cut-off value of new-onset AF duration detected by CIEDs for cardioembolic stroke is still unknown. In previous studies regarding the cut-off value of AF duration, patients who had a history of AF or had received anticoagulant therapies were also included. Therefore, the solo effect of AF on the risk of cardioembolic stroke cannot be reliably evaluated on these studies.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Miyo Nakano, Yusuke Kondo, Masahiro Nakano, Takatsugu Kajiyama, Ryo Ito, Mari Kitagawa, Toshinori Chiba, Satoko Ryuzaki, Yutaka Yoshino Source Type: research
Does atrial fibrillation ablation really reduce stroke rates?
Atrial fibrillation (AF) is increasingly becoming common among older people, and its prevalence is around 1% of the adult population in North America (roughly 2.2 million people). Patients with AF have an increased risk of strokes, heart failure, and subsequent mortality. Although antiarrhythmic drugs for restoring sinus rhythm have failed to reduce these risks, a subanalysis showed that achieving sinus rhythm was associated with halving the mortality but this effect was negated if antiarrhythmic therapy was continued. In fact, the ATHENA (A placebo-controlled, double-blind, parallel-arm Trial to assess the efficacy of dro...
Source: Heart Rhythm - July 22, 2013 Category: Cardiology Authors: Yasuo Okumura Tags: Editorial Commentary Source Type: research
Incidence and prediction of ischemic stroke among atrial fibrillation patients with end-stage renal disease requiring dialysis
Renal dysfunction is a significant risk factor for ischemic stroke in atrial fibrillation (AF). However, the incidence of ischemic stroke and how to predict its occurrence among AF patients with end-stage renal disease (ESRD) are unclear.
Source: Heart Rhythm - June 18, 2014 Category: Cardiology Authors: Tze-Fan Chao, Chia-Jen Liu, Kang-Ling Wang, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Fa-Po Chung, Jo-Nan Liao, Tzeng-Ji Chen, Gregory Y.H. Lip, Shih-Ann Chen Source Type: research
