Po-670-06 efficacy and safety of left atrial appendage occlusion during cardiac surgery to prevent stroke: a systematic review and meta-analysis

Stroke remains one of the significant causes of morbidity and mortality after cardiac surgery. One stroke occurrence is postoperative atrial fibrillation (pAF), with an incidence ranging between 20% and 40%. PAF predisposes to the formation of atrial thrombus. Most thrombus formations observed in the left atrial appendage (LAA) have triggered significant interest as a potential therapeutic target. Current guidelines recommend the administration of direct oral anticoagulants (DOACs) as the preferred therapy to prevent stroke in patients with atrial fibrillation with a CHA2DS2-VASc of ≥ 2.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research