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Newly detected paroxysmal atrial fibrillation after tia and ischaemic stroke on cardiac monitoring: systematic review and meta-analysis in relation to duration of recording
Conclusion Cardiac monitoring after TIA or ischaemic stroke detects clinically important rates of pAF in studies of unselected populations, with high rates of subsequent anticoagulation. A monitoring period of 5–7 days appears to be adequate.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Yiin, G. S., Lovett, N. G., Rothwell, P. M. Tags: Stroke Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Incidence, outcome and future projections of atrial fibrillation-related stroke and systemic embolism at age >=80 years: 10-year results of a population-based study
Conclusion Numbers of AF–related ischaemic strokes at age ≥80 years are projected to treble by 2050, along with numbers of systemic emboli, unless rates of anticoagulation in older patients increase.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Yiin, G. S., Howard, D. P., Paul, N. L., Mehta, Z., Rothwell, P. M. Tags: Stroke Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Short runs of atrial arrhythmia and stroke risk: a European-wide online survey among stroke physicians and cardiologists.
Conclusion Short runs of atrial fibrillation create a dilemma for physicians across Europe. Stroke physicians and cardiologists differ in their diagnosis and management of these patients. PMID: 27929570 [PubMed - in process]
Source: Journal of the Royal College of Physicians of Edinburgh - December 10, 2016 Category: Journals (General) Tags: J R Coll Physicians Edinb Source Type: research

Clinical Stroke prevention in atrial fibrillation.
Authors: Voukalis C, Shantsila E, Lip GY Abstract Oral anticoagulation therapy has reduced the risk of ischaemic stroke and improved the outcomes for patients with atrial fibrillation considerably. The emergence of the non-vitamin K oral anticoagulants as alternatives to vitamin K antagonists has significantly changed the practice of stroke prevention in atrial fibrillation. As the main complication with antithrombotic therapy is bleeding, physicians should always balance the risk of ischaemic stroke against intracranial haemorrhage and intervene where appropriate to reduce both risks. Individual approach is often ...
Source: Journal of the Royal College of Physicians of Edinburgh - June 3, 2017 Category: General Medicine Tags: J R Coll Physicians Edinb Source Type: research

The increasing burden of atrial fibrillation in acute medical admissions, an opportunity to optimise stroke prevention.
Conclusions Atrial fibrillation prevalence is significantly increasing among acute hospital admissions; these patients have high risk of cardioembolic stroke. Careful screening and identification in secondary care can lead to improved rates of anticoagulation. PMID: 29537402 [PubMed - in process]
Source: Journal of the Royal College of Physicians of Edinburgh - March 16, 2018 Category: General Medicine Tags: J R Coll Physicians Edinb Source Type: research

Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation.
Authors: Shahedah KK, Khoo CS, Wan Nur Nafisah WY, Ng CF, Noor Ashikin I, Mohd Naim MY, Syazarina Sharis O, Rozman Z, Wan Asyraf WZ Abstract A 42-year-old female admitted with new-onset atrial fibrillation had a wake-up stroke on the high-dependency unit and the time last seen well (TLSW) was 6.5 h. She suffered left-sided body weakness and her National Institutes of Health Stroke Scale (NIHSS) score was 17. An emergency CT perfusion showed right M1 segment occlusion with more than 50% penumbra. She was given recombinant tissue plasminogen activator (r-tPA) at 9 h from TLSW. An immediate diagnostic angiogram with...
Source: Journal of the Royal College of Physicians of Edinburgh - September 8, 2018 Category: General Medicine Tags: J R Coll Physicians Edinb Source Type: research

Improving detection and management of atrial fibrillation after ischaemic stroke in Glasgow (IMPROVE-AF): A quality improvement project
DISCUSSION: The QIP has improved AF detection, reduced delays associated with conventional cardiac monitoring and prompted early initiation of oral anticoagulation.PMID:36369810 | DOI:10.1177/14782715221120133
Source: Journal of the Royal College of Physicians of Edinburgh - November 12, 2022 Category: General Medicine Authors: Fiona C Johnston Alan C Cameron Elizabeth Colquhoun David L Murdoch Jesse Dawson Azmil H Abdul-Rahim Source Type: research

A practical approach to the new oral anticoagulants used for stroke prevention in patients with atrial fibrillation.
Authors: Bashir S, Al-Mohammed A, Gupta S Abstract This review evaluates the research undertaken in the last six years on the use of new oral anticoagulants for stroke prevention in atrial fibrillation and provides evidence-based answers to common clinical questions. Two types of new oral anticoagulants - direct thrombin (IIa) inhibitors, and Xa inhibitors - are currently available. These drugs have similar pharmacokinetics and pharmacodynamics. They are more predictable than, though in many respects comparable to, warfarin. They do not require frequent laboratory tests, nor do they have a narrow therapeutic window...
Source: Journal of the Royal College of Physicians of Edinburgh - December 10, 2016 Category: Journals (General) Tags: J R Coll Physicians Edinb Source Type: research