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RWD149 Reduction in Ischemic Stroke Rates in Patients With Non-Valvular Atrial Fibrillation During the Period 2013-2020: A Real-Life Study in Spain
The aim of this study is to analyze the variations in the incidence of cardiovascular events and mortality rates in patients with non-valvular atrial fibrillation (NVAF) receiving antithrombotic treatment (VKA, NOAC or antiplatelet drugs) between 2013 and 2020. In addition, this study estimates the impact of these variations in the use of healthcare resources and costs in Spain.
Source: Value in Health - December 1, 2022 Category: International Medicine & Public Health Authors: O Delgado, A Sicras-Mainar, I P érez Román, J Salazar, MI del Campo Alonso, A Echeto, D Vilanova, J Comin-Colet Source Type: research

Sex and gender differences in the use of oral anticoagulants for non-valvular atrial fibrillation: A population-based cohort study in primary health care in catalonia
Conclusion: We described the dose adequacy of patients receiving DOAC, finding a high frequency of underdosing, and significantly higher in women in comparison with men. Adherence was generally high, only with higher levels in women for rivaroxaban. Persistence during the first year of treatment was also high in general, being significantly more persistent women than men in the case of dabigatran and edoxaban. Dose inadequacy, lack of adherence and of persistence can result in less effective and safe treatments. It is necessary to conduct studies analysing sex and gender differences in health and disease.
Source: Frontiers in Pharmacology - February 7, 2023 Category: Drugs & Pharmacology Source Type: research

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