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Deep brain stimulation for stroke: Current uses and future directions
Publication date: Available online 12 October 2017 Source:Brain Stimulation Author(s): Gavin J.B. Elias, Andrew A. Namasivayam, Andres M. Lozano Background Survivors of stroke often experience significant disability and impaired quality of life related to ongoing maladaptive responses and persistent neurologic deficits. Novel therapeutic options are urgently needed to augment current approaches. One way to promote recovery and ameliorate symptoms may be to electrically stimulate the surviving brain. Various forms of brain stimulation have been investigated for use in stroke, including deep brain stimulation (DBS). Objecti...
Source: Brain Stimulation - October 13, 2017 Category: Neurology Source Type: research

Pharmacological Management of Central Post-Stroke Pain: A Practical Guide
Abstract Pain is one of the most troublesome sequelae of stroke. Some of this post-stroke pain is caused by the brain lesion itself; this is called central post-stroke pain (CPSP). Although the prevalence of CPSP is low (1–8 %), persistent, often treatment-resistant, painful sensations are a major problem for stroke patients. The pathogenesis of CPSP remains unknown, but suggested underlying causes include hyperexcitation in the damaged sensory pathways, damage to the central inhibitory pathways, or a combination of the two. For pharmacological treatment, amitriptyline, an adrenergic antidepressant, is current...
Source: CNS Drugs - September 1, 2014 Category: Neurology Source Type: research

Randomized clinical trial of deep brain stimulation for post ‐stroke pain
This article is protected by copyright. All rights reserved.
Source: Annals of Neurology - April 5, 2017 Category: Neurology Authors: Scott F. Lempka, Donald A. Malone, Bo Hu, Kenneth B. Baker, Alexandria Wyant, John Ozinga, Ela B. Plow, Mayur Pandya, Cynthia S. Kubu, Paul J. Ford, Andre G. Machado Tags: Research Article Source Type: research

Diagnosis, Treatment, and Management of Dejerine –Roussy Syndrome: a Comprehensive Review
AbstractPurpose of ReviewPost-stroke pain represents a complex condition with few standardized diagnostic criteria. As such, the array of symptoms is often difficult to categorize and diagnose. Central post-stroke pain (CPSP), also known as Dejerine –Roussy syndrome, presents as painful paresthesia in any part of the body that is usually coupled with sensory abnormalities.Recent FindingsIn patients who had experienced a cerebrovascular accident, CPSP typically affects the same areas of the body that are also impacted by the general motor and sensory deficits that result from stroke. Though it is generally debated, CPSP i...
Source: Current Pain and Headache Reports - July 14, 2020 Category: Neurology Source Type: research