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Condition: Hypertension
Nutrition: Antidoxidants

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Total 80 results found since Jan 2013.

Health benefits of astaxanthin against age-related diseases of multiple organs: A comprehensive review
Crit Rev Food Sci Nutr. 2022 Jun 16:1-66. doi: 10.1080/10408398.2022.2084600. Online ahead of print.ABSTRACTAge-related diseases are associated with increased morbidity in the past few decades and the cost associated with the treatment of these age-related diseases exerts a substantial impact on social and health care expenditure. Anti-aging strategies aim to mitigate, delay and reverse aging-associated diseases, thereby improving quality of life and reducing the burden of age-related pathologies. The natural dietary antioxidant supplementation offers substantial pharmacological and therapeutic effects against various dise...
Source: Atherosclerosis - June 16, 2022 Category: Cardiology Authors: Phaniendra Alugoju V K D Krishna Swamy Naga Venkata Anusha Anthikapalli Tewin Tencomnao Source Type: research

Molecules, Vol. 27, Pages 5100: Tetrahydrocurcumin-Related Vascular Protection: An Overview of the Findings from Animal Disease Models
nov Feng Wang Tetrahydrocurcumin (THC), one of the major metabolites of CUR, possesses several CUR-like pharmacological effects; however, its mechanisms of action are largely unknown. This manuscript aims to summarize the literature on the preventive role of THC on vascular dysfunction and the development of hypertension by exploring the effects of THC on hemodynamic status, aortic elasticity, and oxidative stress in vasculature in different animal models. We review the protective effects of THC against hypertension induced by heavy metals (cadmium and iron), as well as its impact on arterial stiffness and vascular r...
Source: Molecules - August 10, 2022 Category: Chemistry Authors: Li Zhang Changhu Li Sicheng Wang Dimiter Avtanski Nikola Hadzi-Petrushev Vadim Mitrokhin Mitko Mladenov Feng Wang Tags: Review Source Type: research

Air Pollution: Another Threat to HDL Function
Int J Mol Sci. 2022 Dec 24;24(1):317. doi: 10.3390/ijms24010317.ABSTRACTEpidemiological studies have consistently demonstrated a positive association between exposure to air pollutants and the incidence of cardiovascular disease, with the strongest evidence for particles with a diameter < 2.5 μm (PM2.5). Therefore, air pollution has been included among the modifiable risk factor for cardiovascular outcomes as cardiovascular mortality, acute coronary syndrome, stroke, heart failure, and arrhythmias. Interestingly, the adverse effects of air pollution are more pronounced at higher levels of exposure but were also sho...
Source: Atherosclerosis - January 8, 2023 Category: Cardiology Authors: Alice Ossoli Federica Cetti Monica Gomaraschi Source Type: research

Pharmacological and Molecular Insight on the Cardioprotective Role of Apigenin
Nutrients. 2023 Jan 12;15(2):385. doi: 10.3390/nu15020385.ABSTRACTApigenin is a naturally occurring dietary flavonoid found abundantly in fruits and vegetables. It possesses a wide range of biological properties that exert antioxidant, anti-inflammatory, anticancer, and antibacterial effects. These effects have been reported to be beneficial in the treatment of atherosclerosis, stroke, hypertension, ischemia/reperfusion-induced myocardial injury, and diabetic cardiomyopathy, and provide protection against drug-induced cardiotoxicity. These potential therapeutic effects advocate the exploration of the cardioprotective actio...
Source: Atherosclerosis - January 21, 2023 Category: Cardiology Authors: Shilu Deepa Thomas Niraj Kumar Jha Saurabh Kumar Jha Bassem Sadek Shreesh Ojha Source Type: research

< em > In-vitro < /em > antioxidant, lipoxygenase inhibitory, and < em > in-vivo < /em > muscle relaxant potential of the extract and constituent isolated from < em > Diospyros kaki < /em > (Japanese Persimmon)
This study excellently rationalizes the traditional usage of D. kaki in curing various diseases. Furthermore, the docking results indicate, that the isolated compound fits well into the active site of the lipoxygenase, and makes strong interactions with the target protein.PMID:36895410 | PMC:PMC9989937 | DOI:10.1016/j.heliyon.2023.e13816
Source: Atherosclerosis - March 10, 2023 Category: Cardiology Authors: Adil Mujawah Abdur Rauf Sami Bawazeer Abdul Wadood Hassan A Hemeg Saud Bawazeer Source Type: research