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Condition: Ischemic Stroke

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Total 66853 results found since Jan 2013.

Association of Dietary Protein Consumption With Incident Silent Cerebral Infarcts and Stroke: The Atherosclerosis Risk in Communities (ARIC) Study Clinical Sciences
Conclusions— This study supports the notion that consumption of red meat may increase the risk of ischemic stroke. No association between dietary protein intake and silent cerebral infarcts was found.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Haring, B., Misialek, J. R., Rebholz, C. M., Petruski-Ivleva, N., Gottesman, R. F., Mosley, T. H., Alonso, A. Tags: Epidemiology, Computerized Tomography (CT), Ischemic Stroke Clinical Sciences Source Type: research

Efficacy and Safety of Platelet Glycoprotein Receptor Blockade in Aged and Comorbid Mice With Acute Experimental Stroke Basic Sciences
Conclusions— Inhibition of early steps of thrombus formation protects adult and comorbid mice from ischemic stroke. The use of clinically meaningful mouse strains might improve the translation of preclinical stroke research to the clinic.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Kraft, P., Schuhmann, M. K., Fluri, F., Lorenz, K., Zernecke, A., Stoll, G., Nieswandt, B., Kleinschnitz, C. Tags: Animal Models of Human Disease, Hypertension, Treatment, Ischemic Stroke, Atherosclerosis Basic Sciences Source Type: research

Socioeconomic Conditions in Childhood, Adolescence, and Adulthood and the Risk of Ischemic Stroke Clinical Sciences
Conclusions— This study supports the hypothesis that unfavorable childhood socioeconomic conditions are related to ischemic stroke risk, independent of established risk factors and socioeconomic status in adulthood, and fosters the idea that stroke prevention needs to begin early in life.
Source: Stroke - December 28, 2015 Category: Neurology Authors: Becher, H., Palm, F., Aigner, A., Safer, A., Urbanek, C., Buggle, F., Grond-Ginsbach, C., Grau, A. J. Tags: Epidemiology, Primary Prevention, Secondary Prevention, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Short Leukocyte Telomere Length Is Associated With Cardioembolic Stroke Risk in Patients With Atrial Fibrillation Brief Reports
Conclusions— Telomere shortening is associated with cardioembolic stroke risk in patients with AF. Prospective studies are encouraged to establish the value of LTL to improve prediction tools to categorize cardioembolic stroke risk in AF.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Allende, M., Molina, E., Gonzalez-Porras, J. R., Toledo, E., Lecumberri, R., Hermida, J. Tags: Atrial Fibrillation, Risk Factors, Genetics, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Clinical Scales Do Not Reliably Identify Acute Ischemic Stroke Patients With Large-Artery Occlusion Clinical Sciences
Conclusions— Using published cutoffs for triage would result in a loss of opportunity for ≥20% of patients with large-artery occlusion who would be inappropriately sent to a center lacking neurointerventional facilities. Conversely, using cutoffs reducing the false-negative rate to 10% would result in sending almost every patient to a comprehensive stroke center. Our findings, therefore, suggest that intracranial arterial imaging should be performed in all patients with acute ischemic stroke presenting within 6 hours of symptom onset.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Turc, G., Maier, B., Naggara, O., Seners, P., Isabel, C., Tisserand, M., Raynouard, I., Edjlali, M., Calvet, D., Baron, J.-C., Mas, J.-L., Oppenheim, C. Tags: Magnetic Resonance Imaging (MRI), Revascularization, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Atrial Fibrillation Is Associated With a Worse 90-Day Outcome Than Other Cardioembolic Stroke Subtypes Clinical Sciences
Conclusions— AF is associated with an unfavorable 90-day outcome among patients with a CES independent of established risk factors and initial stroke severity. This suggests that AF-specific mechanisms affect CES severity and functional status after CES. If confirmed in future studies, further investigation into the underlying pathophysiological mechanisms may provide novel avenues to AF detection and treatment.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Henninger, N., Goddeau, R. P., Karmarkar, A., Helenius, J., McManus, D. D. Tags: Atrial Fibrillation, Etiology, Ischemic Stroke Clinical Sciences Source Type: research

External Validation of the ASTRAL and DRAGON Scores for Prediction of Functional Outcome in Stroke Clinical Sciences
Conclusions— The ASTRAL and DRAGON scores show an acceptable predictive performance. ASTRAL does not require imaging-data and therefore may have an advantage for the use in prehospital patient assessment. Prospective studies of both scores evaluating the impact of their use on patient outcomes after intravenous thrombolysis and endovascular therapy are needed.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Cooray, C., Mazya, M., Bottai, M., Dorado, L., Skoda, O., Toni, D., Ford, G. A., Wahlgren, N., Ahmed, N. Tags: Prognosis, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Determinants and Outcomes of Stroke Following Percutaneous Coronary Intervention by Indication Clinical Sciences
Conclusions— Hemorrhagic and ischemic stroke complications are uncommon, but serious complications can occur after PCI and are independently associated with worse mortality and major adverse cardiovascular events outcomes in both the elective and acute coronary syndrome setting irrespective of stroke type. Our study provides a better understanding of the risk factors and prognosis of stroke after PCI by procedure type, allowing physicians to provide more informed advice around stroke risk after PCI and counsel patients and their families around outcomes if such neurological complications occur.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Myint, P. K., Kwok, C. S., Roffe, C., Kontopantelis, E., Zaman, A., Berry, C., Ludman, P. F., de Belder, M. A., Mamas, M. A., on behalf of the British Cardiovascular Intervention Society and the National Institute for Cardiovascular Outcomes Research Tags: Percutaneous Coronary Intervention, Intracranial Hemorrhage, Ischemic Stroke Clinical Sciences Source Type: research

First-Ever Stroke and Transient Ischemic Attack Incidence and 30-Day Case-Fatality Rates in a Population-Based Study in Argentina Brief Reports
Conclusions— This study provides the first prospective population-based stroke and TIA incidence and case-fatality estimate in Argentina. First-ever stroke incidence was lower than that reported in previous Latin-American studies, but first-ever TIA incidence was higher. Thirty-day case-fatality rates were similar to those of other population-based Latin-American studies.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Bahit, M. C., Coppola, M. L., Riccio, P. M., Cipriano, L. E., Roth, G. A., Lopes, R. D., Feigin, V. L., Borrego Guerrero, B., De Martino, M., Diaz, A., Ferrante, D., Funaro, F., Lavados, P., Lewin, M. L., Lopez, D. H., Macarrone, P., Marciello, R., Marino Tags: Epidemiology, Race and Ethnicity, Mortality/Survival, Cerebrovascular Disease/Stroke, Transient Ischemic Attack (TIA) Brief Reports Source Type: research

Eligibility and Predictors for Acute Revascularization Procedures in a Stroke Center Clinical Sciences
Conclusions— Of patients arriving within 6 hours at a comprehensive stroke center, 10.5% are EVT eligible according to AHA/ASA criteria, 17.7% according to criteria resembling randomized controlled trials, and twice as many patients are IVT eligible (36.2%).
Source: Stroke - June 26, 2016 Category: Neurology Authors: Vanacker, P., Lambrou, D., Eskandari, A., Mosimann, P. J., Maghraoui, A., Michel, P. Tags: Ischemic Stroke Clinical Sciences Source Type: research

Low Circulating Acute Brain-Derived Neurotrophic Factor Levels Are Associated With Poor Long-Term Functional Outcome After Ischemic Stroke Brief Reports
Conclusions— Circulating concentrations of BDNF protein are lowered in the acute phase of ischemic stroke, and low levels are associated with poor long-term functional outcome. Further studies are necessary to confirm these associations and to determine the predictive value of BDNF in stroke outcomes.
Source: Stroke - June 26, 2016 Category: Neurology Authors: Stanne, T. M., Aberg, N. D., Nilsson, S., Jood, K., Blomstrand, C., Andreasson, U., Blennow, K., Zetterberg, H., Isgaard, J., Svensson, J., Jern, C. Tags: Biomarkers, Etiology, Ischemic Stroke Brief Reports Source Type: research

Tissue-Type Plasminogen Activator-A296-299 Prevents Impairment of Cerebral Autoregulation After Stroke Through Lipoprotein-Related Receptor-Dependent Increase in cAMP and p38 Basic Sciences
Conclusions— tPA-A296–299 prevents impairment of cerebral autoregulation after stroke through an LRP-dependent increase in cAMP and p38.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Armstead, W. M., Riley, J., Yarovoi, S., Higazi, A. A.-R., Cines, D. B. Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Neuroprotectants Basic Sciences Source Type: research

Influence of Distance to Scene on Time to Thrombolysis in a Specialized Stroke Ambulance Brief Reports
Conclusions— In a metropolitan area such as Berlin, time benefits justify a specialized stroke ambulance service up to a mean travel time of 18 minutes from base station. Clinical Trial Registration— URL: https://www.clinicaltrials.gov. Unique identifier: NCT01382862.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Koch, P. M., Kunz, A., Ebinger, M., Geisler, F., Rozanski, M., Waldschmidt, C., Weber, J. E., Wendt, M., Winter, B., Zieschang, K., Bollweg, K., Kaczmarek, S., Endres, M., Audebert, H. J. Tags: Health Services, Quality and Outcomes, Ischemic Stroke Brief Reports Source Type: research

Effects of Alteplase for Acute Stroke on the Distribution of Functional Outcomes: A Pooled Analysis of 9 Trials Clinical Sciences
Conclusions— Treatment with intravenous alteplase initiated within 4.5 hours of stroke onset increases the chance of achieving an improved level of function for all patients across the age spectrum, including the over 80s and across all severities of stroke studied (top versus bottom fifth means: 22 versus 4); the earlier that treatment is initiated, the greater the benefit.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Lees, K. R., Emberson, J., Blackwell, L., Bluhmki, E., Davis, S. M., Donnan, G. A., Grotta, J. C., Kaste, M., von Kummer, R., Lansberg, M. G., Lindley, R. I., Lyden, P., Murray, G. D., Sandercock, P. A. G., Toni, D., Toyoda, K., Wardlaw, J. M., Whiteley, Tags: Treatment, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Clinical Sciences Source Type: research

Parental Care-Seeking Behavior and Prehospital Timelines of Care in Childhood Arterial Ischemic Stroke Brief Reports
Conclusions— Stroke recognition and care-seeking behavior are suboptimal, with less than half the parents considering stroke or calling an ambulance. Initiatives are required to educate parents about appropriate actions to facilitate time-critical interventions.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Mackay, M. T., Stojanovski, B., Mosley, I., Churilov, L., Donnan, G. A., Monagle, P. Tags: Pediatrics, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research