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Tumor Treating Fields (TTF) with Triple Chemotherapy for Recurrent Glioblastoma (P1.177)
Conclusions:Therapies with TTF plus TBC demonstrates superior OS benefit for recurrent GBM with moderate, but manageable side effects. A prospective study of TTF plus TBC for recurrent GBM is warranted.Study Supported by: Dr. Marnie Rose FoundationDisclosure: Dr. Zhu has received personal compensation for activities with Novocure, and Prime Oncology. Dr. Zhu has received research support from Novocure, Inc., Five Prime Therapeutics, Immuno-Cellular Inc., DEKK-TEC. Dr. Lu has nothing to disclose. Dr. Rao has nothing to disclose. Dr. Zhu has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Zhu, J.-J., Lu, G., Rao, M., Zhu, P. Tags: Neuro-oncology: Gliomas I Source Type: research

Giant-Cell Arteritis Presenting as Isolated Bilateral CN-VI Palsies: A Rare Case Report of a 65 Year Male. (P2.378)
Conclusions:GCA is the most prevalent systemic vasculitis in the elderly. It can present with a wide variety of symptoms ranging from fatigue, headache, visual loss, and even stroke. However as noted in this case, isolated CN-VI palsy can be a very rare, early manifestation of GCA. As GCA responds well to corticosteroid therapy, prompt diagnosis and treatment is critical to prevent and/or limit neurologic sequelae. As highlighted by this case, in the event of recurrent incidents and absence of other diagnosis; GCA should be considered even if headache is absent.Disclosure: Dr. Lunagariya has nothing to disclose. Dr. Patel ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Lunagariya, A., Patel, U., Kotadiya, F., Wilson, C. Tags: CNS Inflammatory Diseases and Differential Diagnosis II Source Type: research

Clinical Reasoning: Myriad manifestations of a global infectious disease
A 21-year-old right-handed Cambodian woman with no history of headache presented with 2 weeks of progressive bifrontal headache. She had no sick contacts or recent travel. She moved to the United States at age 3 years. She had no fever, nuchal rigidity, photophobia, phonophobia, nausea, or vomiting. She had a recent history of weight loss and palpitations. There was no tobacco or illicit drug use or high-risk sexual behavior. She was not pregnant and denied contraception use.
Source: Neurology - June 5, 2016 Category: Neurology Authors: Prabhu, A. M., Raghupathi, R., Dissin, J. Tags: Stroke in young adults, Vasculitis, Meningitis RESIDENT AND FELLOW SECTION Source Type: research

An Unusual Cause Of Recurrent Ischemic Stroke: Trousseau's Syndrome From Gastric Cancer (P4.231)
CONCLUSIONS: Trousseau’s Syndrome must be considered in those presenting with recurrent strokes with an otherwise negative embolic work up especially in the elderly and those with cancer risk factors. It must prompt the clinician to look for an associated malignancy.Disclosure: Dr. JADEJA has nothing to disclose. Dr. Johnson has nothing to disclose. Dr. Soetanto has nothing to disclose. Dr. Nalleballe has nothing to disclose. Dr. DeNiro has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Graber has received personal compensation for activities with Stemedica Inc., Novocure Inc., and Biogen Idec.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Jadeja, N., Johnson, J., Soetanto, A., Nalleballe, K., DeNiro, L., Qureshi, I., Graber, J. Tags: Neuro-oncology: Paraneoplastic Disorders Source Type: research

Acute Cerebral Infarction as the Presenting Feature of anti-PL-7 Anti-Synthetase Syndrome (P5.126)
CONCLUSIONS: Anti-PL7 is one of eight known aminoacyl-tRNA synthetase (ARS) antibodies. Emerging evidence would suggest that each ARS antibody has a distinct phenotype. There is one report of acute infarction with cerebral vasculitis and anti-Jo1 ARS autoantibody. This is the first report of stroke in association with anti-PL7 anti-synthetase syndrome. Increased recognition of this disorder will allow for better delineation of the phenotype. Study Supported by:Disclosure: Dr. McNicholas has nothing to disclose. Dr. Henry has nothing to disclose. Dr. Ryan has received personal compensation for activities with Novartis, Merc...
Source: Neurology - April 8, 2015 Category: Neurology Authors: McNicholas, N., Henry, M., Ryan, A. Tags: Cerebrovascular Disease and Interventional Neurology: Biomarkers and Emerging Science Source Type: research

Effect of weight loss surgery on cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke in overweight and obese post-menopausal women (I12-5C)
Conclusions: We did not observe any significant effect of weight loss surgery on reduction of cardiovascular endpoint of death, nonfatal myocardial infarction, or nonfatal stroke.Disclosure: Dr. Saeed has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Saeed, O., Malik, A., Qureshi, A. Tags: Obesity and Neurological Disorders Poster Presentations Source Type: research

Body Mass Index and Stroke Subtype in a Young Adult Stroke Population (I12-5D)
CONCLUSIONS: In our group of young adult stroke patients, we found the highest BMI in the group with intracranial atherosclerosis. Although this group represented a small number of patients, this young adult population is at increased risk for future strokes. It is important to educate them on lifestyle modifications such as weight loss and exercise in addition to the treatment of hypertension, diabetes mellitus and hyperlipidemia.Disclosure: Dr. Youn has nothing to disclose. Dr. Aung has nothing to disclose. Dr. Afrasiabi has nothing to disclose. Dr. Clark has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Youn, J., Aung, T., Afrasiabi, M., Clark, J. Tags: Obesity and Neurological Disorders Poster Presentations Source Type: research

Effect of weight loss surgery on cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke in overweight and obese post-menopausal women (P1.071)
Conclusions: We did not observe any significant effect of weight loss surgery on reduction of cardiovascular endpoint of death, nonfatal myocardial infarction, or nonfatal stroke.Disclosure: Dr. Saeed has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Saeed, O., Malik, A., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology Source Type: research

Body Mass Index and Stroke Subtype in a Young Adult Stroke Population (P7.126)
CONCLUSIONS: In our group of young adult stroke patients, we found the highest BMI in the group with intracranial atherosclerosis. Although this group represented a small number of patients, this young adult population is at increased risk for future strokes. It is important to educate them on lifestyle modifications such as weight loss and exercise in addition to the treatment of hypertension, diabetes mellitus and hyperlipidemia.Disclosure: Dr. Youn has nothing to disclose. Dr. Aung has nothing to disclose. Dr. Afrasiabi has nothing to disclose. Dr. Clark has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Youn, J., Aung, T., Afrasiabi, M., Clark, J. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke in Young Source Type: research

The Rhino Without It's Sugar (P2.324)
We present a case of a non-diabetic patient with stroke like symptoms that was determined to be due to mucormycosis invading the sphenoid sinus.A 64 year old female was admitted for slurred speech and right-sided weakness. She was brought to the ER after being found unresponsive. Family members stated she had been experiencing difficulty speaking, and mild right facial weakness. She has been complaining of headaches for the past seven months and 15 pound weight loss. On admission, temperature was 98.4°F, BP 122/77, PR 78, and RR 18. Exam was significant for right-sided facial asymmetry/droop, expressive aphasia, and sl...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Kahlon, J., Gahley, H., Sonpal, N., Graham, R. Tags: Fungi, Parasites, and Other Pathogens Source Type: research

Acute Stroke in Young Women Taking Phentermine (P01.249)
CONCLUSIONS: We present here two patients with mild underlying cerebrovascular risk factors who presented with acute stroke after taking diet pills containing phentermine. The public should be aware of the possible association between stroke and phentermine. More long-term outcomes research is necessary to understand the safety of phentermine-containing diet pills. Patients with cerebrovascular risk factors should be cautious about using Phentermine containing diet pills.Disclosure: Dr. Smit has nothing to disclose. Dr. Cutting has received personal compensation for activities with F1000. Dr. Conners has nothing to disclos...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Smit, L., Cutting, S., Conners, J., Lee, V., Song, S. Tags: P01 Cerebrovascular Disease I Source Type: research