• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Effective treatment of choreaballism due to an MT ‐CYB variant with haloperidol, tetrabenazine, and antioxidants
Cerebral CT showing bilateral putaminal calcifications of a patient with multisystem mitochondrial disorder due to the variant 15043G  >  A inMT-CYB. Key Clinical MessageHypokinetic and hyperkinetic movement disorders are a common phenotypic feature of mitochondrial disorders. Choreaballism has been reported particularly in patients with mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome and in maternally inherited diabetes and deafness syndrome. The pathophysiological basis of movement disorders in mitochondrial disorders is the involvement of the basal ganglia or the midbrain. Haloper...
Source: Clinical Case Reports - June 21, 2023 Category: General Medicine Authors: Josef Finsterer, Ritwik Ghosh Tags: CASE REPORT Source Type: research

Quadri-chamber cardiac thrombi in alcoholic cardiomyopathy: a rare though ominous finding
We report a case of alcoholic cardiomyopathy with an alarming finding of thrombi in all cardiac chambers. Echocardiographic evidence of quadri-chamber intracardiac thrombi has rarely been described in the literature. Case A 48-year-old man with history of chronic alcoholism presented with progressive breathlessness of 1 year's duration. Cardiovascular examination showed sinus tachycardia and evidence of congestive cardiac failure. A transthoracic echocardiogram (TTE) showed dilated cardiac chambers, severe biventricular global dysfunction with an alarming finding of thrombi...
Source: Postgraduate Medical Journal - July 16, 2013 Category: Journals (General) Authors: Singh, Y., Singla, V., Singh, B., Rajendran, R., Khandenahally, R. S., Manjunath, C. N. Tags: Cardiomyopathy, Immunology (including allergy), Drugs: cardiovascular system, Echocardiography, Heart failure, Stroke, Hypertension, Malnutrition, Interventional cardiology, Ischaemic heart disease, Venous thromboembolism, Alcohol-related disorders, Drugs Source Type: research