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Bioinformatic Analysis of Exosomal MicroRNAs of Cerebrospinal Fluid in Ischemic Stroke Rats After Physical Exercise
Neurochem Res. 2021 Mar 11. doi: 10.1007/s11064-021-03294-1. Online ahead of print.ABSTRACTPhysical exercise is beneficial to the structural and functional recovery of post-ischemic stroke, but its molecular mechanism remains obscure. Herein, we aimed to explore the underlying mechanism of exercise-induced neuroprotection from the perspective of microRNAs (miRNAs). Adult male Sprague-Dawley (SD) rats were randomly distributed into 4 groups, i.e., the physical exercise group with the transient middle cerebral artery occlusion (tMCAO) surgery (PE-IS, n = 28); the physical exercise group without tMCAO surgery (PE, n = 6); the...
Source: Neurochemical Research - March 12, 2021 Category: Neuroscience Authors: Mudan Huang Chongjun Xiao Liying Zhang Lili Li Jing Luo Lilin Chen Xiquan Hu Haiqing Zheng Source Type: research