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Artificial intelligence-enabled retinal vasculometry for prediction of circulatory mortality, myocardial infarction and stroke
CONCLUSION: RV offers an alternative predictive biomarker to traditional risk-scores for vascular health, without the need for blood sampling or blood pressure measurement. Further work is needed to examine RV in population screening to triage individuals at high-risk.PMID:36195457 | DOI:10.1136/bjo-2022-321842
Source: The British Journal of Ophthalmology - October 4, 2022 Category: Opthalmology Authors: Alicja Regina Rudnicka Roshan Welikala Sarah Barman Paul J Foster Robert Luben Shabina Hayat Kay-Tee Khaw Peter Whincup David Strachan Christopher G Owen Source Type: research

Risks of posterior segment ocular ischaemic events in patients with systemic lupus erythematosus: a population-based cohort study in Taiwan
CONCLUSIONS: SLE increases the risk of developing OIE. Systemic comorbidities and higher dosage of steroid in patients with SLE are associated with severe ocular ischaemic complications.PMID:35922126 | DOI:10.1136/bjo-2022-321653
Source: The British Journal of Ophthalmology - August 3, 2022 Category: Opthalmology Authors: Yi-Ran Chiou Yu-Sheng Chang Chin-Fang Su Tzu-Hao Li Chien-Chih Lai De-Kuang Hwang Fang-Yi Wu Yu-Fan Chang Source Type: research

Nationwide trends in emergency department utilisation for acute retinal ischaemia in the USA, 2011-2018
CONCLUSION: Of the estimated 48 000 patients with TMVL or RAO annually in the USA, few are evaluated in the ED, and admission rates are less than for transient ischaemic attack or ischaemic stroke and are decreasing over time.PMID:35760457 | DOI:10.1136/bjo-2022-321418
Source: The British Journal of Ophthalmology - June 27, 2022 Category: Opthalmology Authors: Ali G Hamedani Lindsey B De Lott Allison W Willis Source Type: research

Ocular and systemic determinants of perifoveal and macular vessel parameters in healthy African Americans
CONCLUSIONS: When interpreting OCTA images in a clinical setting, it is important to consider the effects ocular and systemic characteristics may have on the macular microcirculation.PMID:34740885 | DOI:10.1136/bjophthalmol-2021-319675
Source: The British Journal of Ophthalmology - November 6, 2021 Category: Opthalmology Authors: Grace M Richter Jae Chang Lee Nasir Khan Alexander Vorperian Brennan Hand Bruce Burkemper Xiao Zhou Zhongdi Chu Ruikang Wang Rohit Varma Amir H Kashani Source Type: research

Safety of 5914 intravitreal ziv-aflibercept injections.
CONCLUSION: This constitutes the largest pooled safety report on IVZ use and includes patients from 14 centres distributed across the globe. It shows that IVZ has an acceptable ocular and systemic safety profile with incidences of adverse events similar to those of other vascular endothelial growth factor inhibitory drugs. The analysis supports the continued use of IVZ in various retinal disorders. PMID: 30099379 [PubMed - as supplied by publisher]
Source: The British Journal of Ophthalmology - August 11, 2018 Category: Opthalmology Authors: Singh SR, Stewart MW, Chattannavar G, Ashraf M, Souka A, ElDardeery M, Wadhwa N, Sarvaiya C, Mansour AM, Marashi A, Ramchandani S, Braimah IZ, Jabbarpoor Bonyadi MH, Ramezani A, Soheilian M, de Oliveira Dias JR, de Andrade GC, Maia A, Rodrigues EB, Farah Tags: Br J Ophthalmol Source Type: research