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High Contrast Detection of Carotid Neothrombus with Strong Near-Infrared Absorption Selenium Nanosphere Enhanced Photoacoustic Imaging
CONCLUSION: The superior PA signal of Se@PPy nanomaterials can identify the extent of atherosclerotic carotid lesions, demonstrating the feasibility of PA imaging technology in diagnosing carotid thrombosis lesion formation. This study demonstrates nanocomposites and PA techniques for imaging and diagnosing carotid thrombosis in vivo.PMID:37520300 | PMC:PMC10377622 | DOI:10.2147/IJN.S404743
Source: Atherosclerosis - July 31, 2023 Category: Cardiology Authors: Fengbing He Wenzhong Hou Yintao Lan Weijian Gao Mengyu Zhou Jinghang Li Shutong Liu Bin Yang Jian Zhang Source Type: research

The role of glutathione peroxidase-1 in health and disease
Free Radic Biol Med. 2022 Jun 9:S0891-5849(22)00224-6. doi: 10.1016/j.freeradbiomed.2022.06.004. Online ahead of print.ABSTRACTGlutathione peroxidase 1 (GPx1) is an important cellular antioxidant enzyme that is found in the cytoplasm and mitochondria of mammalian cells. Like most selenoenzymes, it has a single redox-sensitive selenocysteine amino acid that is important for the enzymatic reduction of hydrogen peroxide and soluble lipid hydroperoxides. Glutathione provides the source of reducing equivalents for its function. As an antioxidant enzyme, GPx1 modulates the balance between necessary and harmful levels of reactive...
Source: Atherosclerosis - June 12, 2022 Category: Cardiology Authors: Diane E Handy Joseph Loscalzo Source Type: research

Supplemental Vitamins and Minerals for Cardiovascular Disease Prevention and Treatment
The objective of this study is to explore the current literature supporting the use oral multivitamins and multi/minerals (OMVMs) for cardiovascular diseases (CVD) treatment and prevention.Recent FindingsData on multivitamins, vitamin C and D, coenzyme Q, calcium, and selenium, has showed no consistent benefit for the prevention of CVD, myocardial infarction, or stroke, nor was there a benefit for all-cause mortality to support their routine supplementation. Folic acid alone and B vitamins with folic acid, B6 and B12, reduce stroke, whereas niacin and antioxidants are associated with an increased risk of all-cause mortalit...
Source: Current Cardiology Reports - February 13, 2020 Category: Cardiology Source Type: research