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Prognostic Significance of Fragmented QRS in Patients with Acute Ischemic Stroke
Stroke is a leading cause of mortality and morbidity in developed countries1 and has a strong relationship with cardiovascular system disorders.2 Due to this relationship, the connection between brain and heart has become increasingly important and neurocardiology has emerged as a popular concept over the recent years.3 Electrocardiographic abnormalities and various cardiac arrhythmias occurring especially after stroke support this phenomenon.4 ST segment and/or T-wave abnormalities without myocardial ischemia,5 left axis deviation, QT prolongation,6 QT dispersion,7 atrial fibrillation (AF), sinus tachycardia, ventricular ...
Source: Journal of Stroke and Cerebrovascular Diseases - July 14, 2021 Category: Neurology Authors: Irfan Sahin, Orkhan Karimov, Adem Atici, Hasan Ali Barman, Sevil Tugrul, Sevgi Ozcan, Ramazan Asoglu, Didem Celik, Ertugrul Okuyan, Nilufer Kale Source Type: research

Protocatechuic Acid Prevents Early Hour Ischemic Reperfusion Brain Damage by Restoring Imbalance of Neuronal Cell Death and Survival Proteins
Objective: To investigate the neuroprotective effect of protocatechuic acid (PCA) on cell death/survival protein imbalance in a rat model of middle cerebral artery occlusion and reperfusion. Methods: Focal ischemia was induced by middle cerebral artery occlusion in adult male Wistar rats and confirmed by measuring infarction of brain by 2,3,5-Triphenyltetrazolium chloride (TTC) staining. Rats were treated with vehicle or PCA at 10, 30 or 50 mg/kg dose intraperitoneally and subjected to neurological deficits or beam walk assessment at 24 h of reperfusion.
Source: Journal of Stroke and Cerebrovascular Diseases - December 4, 2020 Category: Neurology Authors: Swapnil Kale, Lopmudra P. Sarode, Amol Kharat, Saurabh Ambulkar, Anand Prakash, Amul J. Sakharkar, Rajesh R. Ugale Source Type: research