• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Chemical Composition, Protective Effects, and Mechanisms of Volatile Oil from Fructus Gleditsiae Abnormalis with Nasal Administration against Ischemic Injury in HFD and MCAO-Induced Rats
This study is aimed to analyze the constituents of the volatile oil in FGA (VOFGA) using gas chromatography coupled with mass spectrometry (GC-MS) and explore the underlying effects and mechanisms of VOFGA in the prevention and treatment of ischemia stroke. An in vivo ischemia model was constructed by combination treatment of high-fat diet (HFD) and middle cerebral artery occlusion (MCAO) method. After administration, the cerebral infarction volume, the brain water content, hemorheology, blood lipids, inflammatory factors, oxidative stress indicators, Bax, Bcl-2, and cleaved caspase-3 and histological examination (HE) were...
Source: Evidence-based Complementary and Alternative Medicine - November 11, 2021 Category: Complementary Medicine Authors: Chengyue Luo Yumei Wu Xiaolan Chen Wei Han Jing Wan Nana Dong Bili Deng Dereje Kebebe Source Type: research

Tetrahydropalmatine Alleviates Hyperlipidemia by Regulating Lipid Peroxidation, Endoplasmic Reticulum Stress, and Inflammasome Activation by Inhibiting the TLR4-NF- < em > κ < /em > B Pathway
In conclusion, these data indicate that THP attenuates HLP through a variety of effects, including antioxidative stress, anti-ER stress, and anti-inflammatory effects. In addition, THP also inhibited the TLR4-NF-κB signaling pathway in golden hamsters.PMID:34760017 | PMC:PMC8575622 | DOI:10.1155/2021/6614985
Source: Evidence-based Complementary and Alternative Medicine - November 11, 2021 Category: Complementary Medicine Authors: Ke Ding Linjun Chen Jiaqi He Jiahong Wang Chaohui Yu Hui Wang Source Type: research

Moxibustion-Simulating Bipolar Radiofrequency Suppresses Weight Gain and Induces Adipose Tissue Browning via Activation of UCP1 and FGF21 in a Mouse Model of Diet-Induced Obesity.
Conclusion: Heat stimulation by M-RF treatment induced upregulation of UCP1 and FGF21 expression in serum and/or WATs, which was correlated with reduced total body and WAT weight gain in DIO mice. PMID: 30275865 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - October 4, 2018 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research