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Specialty: Allergy & Immunology
Nutrition: Ginseng
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Total 2 results found since Jan 2013.
Ginsenoside Rd attenuates cerebral ischemia/reperfusion injury by exerting an anti-pyroptotic effect via the miR-139-5p/FoxO1/Keap1/Nrf2 axis
Int Immunopharmacol. 2022 Feb 3;105:108582. doi: 10.1016/j.intimp.2022.108582. Online ahead of print.ABSTRACTPyroptosis mediated by nucleotide-binding oligomerization domain (NOD)-like receptor 3 (NLRP3) inflammasome is implicated in cerebral ischemia/reperfusion (I/R) injury. Ginsenoside Rd (Rd), a monomer component of Panax ginseng and Panax notoginseng, is reported to confer neuroprotection in brain injury models. However, the role of pyroptosis in Rd-mediated neuroprotection following cerebral I/R has not been investigated. We aimed to confirm the neuroprotective function and underlying mechanisms of Rd on pyroptosis a...
Source: International Immunopharmacology - February 6, 2022 Category: Allergy & Immunology Authors: Yiqin Yao Sheng Hu Chunxue Zhang Qun Zhou Hui Wang Ya Yang Chao Liu Haiyan Ding Source Type: research
