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Source: Experimental and Therapeutic Medicine
Management: Food and Drug Administration (FDA)
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Total 8 results found since Jan 2013.
Dl-butylphthalide inhibits rotenone-induced oxidative stress in microglia via regulation of the Keap1/Nrf2/HO-1 signaling pathway
Exp Ther Med. 2021 Jun;21(6):597. doi: 10.3892/etm.2021.10029. Epub 2021 Apr 9.ABSTRACTActivated microglia are a source of superoxide which often increases oxidative stress in the brain microenvironment, increase production of reactive oxygen species (ROS) and directly or indirectly lead to dopaminergic neuronal death in the substantia nigra. Thus superoxide contributes to the pathogenesis of Parkinson's disease (PD). Evidence suggests that mitochondria are the main source of ROS, which cause oxidative stress in cells. Levels of ROS are thus associated with the function of the mitochondrial complex. Therefore, protecting t...
Source: Experimental and Therapeutic Medicine - April 22, 2021 Category: General Medicine Authors: Rixin Luo Lihong Zhu Zhaohao Zeng Ruiyi Zhou Jiawei Zhang Shu Xiao Wei Bi Source Type: research
