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Source: Frontiers in Neurology
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Total 76 results found since Jan 2013.

Prospective collection of blood plasma samples to identify potential biomarkers for the prehospital stroke diagnosis (ProGrEss-Bio): study protocol for a multicenter prospective observational study
This study will evaluate whether a single blood biomarker or a combination of biomarkers can distinguish patients with AIS and ICH from patients with stroke and SM in the early phase after symptom onset in the prehospital setting. In addition, the kinetics of blood biomarkers in AIS and ICH patients will be investigated. Our goal is to evaluate new ways to reliably diagnose stroke in the prehospital setting and thus accelerate the application of evidence-based therapies to stroke patients.
Source: Frontiers in Neurology - July 6, 2023 Category: Neurology Source Type: research

Connectomic insight into unique stroke patient recovery after rTMS treatment
This study demonstrates for the first time the feasibility of using individualized connectivity analyses in differentiating unique phenotypes in rTMS treatment responses and recovery. This personalized connectomic approach may be utilized in the future to better understand patient recovery trajectories with neuromodulatory treatment.
Source: Frontiers in Neurology - July 6, 2023 Category: Neurology Source Type: research

Computed tomography angiography-based radiomics model for predicting carotid atherosclerotic plaque vulnerability
This study aimed to identify radiomic features associated with the neovascularization of CAP and construct a prediction model for CAP vulnerability based on radiomic features. CTA data and clinical data of patients with CAPs who underwent CTA and CEUS between January 2018 and December 2021 in Beijing Hospital were retrospectively collected. The data were divided into a training cohort and a testing cohort using a 7:3 split. According to the examination of CEUS, CAPs were dichotomized into vulnerable and stable groups. 3D Slicer software was used to delineate the region of interest in CTA images, and the Pyradiomics package...
Source: Frontiers in Neurology - June 16, 2023 Category: Neurology Source Type: research

Neurosyphilis with positive anti-N-methyl-D-aspartate receptor antibody: a case report
A case of neurosyphilis with a positive anti-N-methyl-D-aspartate receptor (NMDAR) antibody was reported. A 54-year-old man who presented with acute memory deficits was admitted to our hospital. Acute ischemic stroke (AIS) was initially considered, and he was prescribed intravenous thrombolysis with recombinant tissue-type plasminogen activator (rt-PA). However, the intermittent onset of episodic memory and orientation disorder still occurred. No diffusion restriction was indicated by magnetic resonance imaging (MRI), and subclinical seizures were frequently found by electroencephalogram (EEG). Rapid plasma reagin (RPR) te...
Source: Frontiers in Neurology - May 18, 2023 Category: Neurology Source Type: research

Associations of lesion location, structural disconnection, and functional diaschisis with depressive symptoms post stroke
DiscussionBased on our results, and other recent lesion studies, we see growing evidence for a prominent role of right frontostriatal brain circuits in PSDS.
Source: Frontiers in Neurology - May 17, 2023 Category: Neurology Source Type: research

Patent foramen ovale closure in non-elderly and elderly patients with cryptogenic stroke: a hospital-based cohort study
DiscussionPFO closure was associated with a reduced risk of the primary outcome in patients with PFO and CS in our total cohort, which included non-elderly and elderly patients. Compared to those without PFO closure, elderly patients with PFO closure had a better functional outcome at 180 days. PFO closure might be considered in selected elderly patients with PFO.
Source: Frontiers in Neurology - May 16, 2023 Category: Neurology Source Type: research

High prevalence of abdominal aortic aneurysm in older men with cerebrovascular disease: Evaluation of a local screening program
This report evaluates the results of a decade's operation of a local screening program for AAA in this selected neurologic population.MethodsMen aged ≥60 years and admitted to the neurology ward of a community-based hospital in the Netherlands from 2006 to 2017 with a diagnosis of TIA or stroke were selected for screening. The diameter of the abdominal aorta was assessed by abdominal ultrasonography. Patients with detected AAA were referred for evaluation by a vascular surgeon.ResultsAAA was detected in 72 of 1,035 screened patients (6.9%). AAAs with a diameter of 3.0–3.9 cm accounted for 61.1% of the total aneurysms f...
Source: Frontiers in Neurology - April 11, 2023 Category: Neurology Source Type: research

Current status and future aspects in the Japan Stroke Data Bank
The Japanese National Plan for the Promotion of Measures Against Cerebrovascular and Cardiovascular Diseases was formulated on October 27, 2020. One purpose of this plan was to promote research on cerebrovascular and cardiovascular diseases. Therefore, it is necessary to clarify the actual status of stroke treatment in Japan and operate a national stroke database with high public interest completely and accurately. The Japan Stroke Data Bank (JSDB; https://strokedatabank.ncvc.go.jp/en/) was established by the Ministry of Health, Labor and Welfare Scientific Research in Shimane University (Shimane, Japan) in 1999 and was tr...
Source: Frontiers in Neurology - March 23, 2023 Category: Neurology Source Type: research

Stroke territory and atherosclerosis in ischemic stroke patients with a history of migraine with aura
DiscussionCryptogenic and cerebellar stroke and fewer vascular risk factors and clinical atherosclerosis seem to characterize stroke patients with MA.
Source: Frontiers in Neurology - February 27, 2023 Category: Neurology Source Type: research

Case report: A case of abrupt stroke as the first symptom of neurobrucellosis
In this study, we report the case of a patient with neurobrucellosis who was hospitalized in the First People's Hospital of Lianyungang in September 2022; the primary symptom was weakness in the left limb for 14 h. The patient was discharged after receiving symptomatic and anti-Brucella medication.
Source: Frontiers in Neurology - February 22, 2023 Category: Neurology Source Type: research

Stroke profile and care during the COVID-19 pandemic: What changed and what did not? A prospective cohort from Joinville, Brazil
This study aims to investigate the impact of COVID-19 pandemic on stroke profile and care in Joinville, Brazil.MethodsA prospective population-based cohort enrolled the first-ever cerebrovascular events in Joinville, Brazil, and a comparative analyzes was conducted between the first 12 months following COVID-19 restrictions (starting March 2020) and the 12 months just before. Patients with transient ischemic attack (TIA) or stroke had their profiles, incidences, subtypes, severity, access to reperfusion therapy, in-hospital stay, complementary investigation, and mortality compared.ResultsThe profiles of TIA/stroke patients...
Source: Frontiers in Neurology - February 16, 2023 Category: Neurology Source Type: research

Ethnodemographic characterization of stroke incidence and burden of disease in hospital discharge records in Ecuador
DiscussionDifferences in the burden of disease by ethnic group are likely to reflect differential access to care by region and socio-economic group, both of which are frequently correlated with ethnic composition in Ecuador. Equitable access to health services remains an important challenge in the country. The gender discrepancy in fatality rates suggests that there is a need for targeted educational campaigns to identify stroke signs early, especially in the female population.
Source: Frontiers in Neurology - February 8, 2023 Category: Neurology Source Type: research

National stroke management plan in Uruguay: Challenges and opportunities
Stroke accounts for 5.5% of the national Global Burden of Disease (GBD) and ~2,000 deaths per year in Uruguay. To respond to this medical emergency, the Ministry of Public Health (MPH) of Uruguay devised the National Stroke Plan (NSP). Scientific associations, universities, scholars, and patient organizations, both at the national and international levels, took part in the process, which ended with the generation of the national stroke management guidelines, including measures based on the best evidence available. This was accompanied by presidential regulatory decrees and several ordinances that set the foundations of the...
Source: Frontiers in Neurology - February 1, 2023 Category: Neurology Source Type: research

Prism adaptation combined with eye movement training for unilateral spatial neglect after stroke: Study protocol for a single-blind prospective, randomized controlled trial
This study will explore the effects of 10 sessions of combined interventions (PA & EMT) on USN and functional capacity. This study has the potential to identify a new, evidence-based treatment option and provide new ideas for the treatment of USN.Ethics and disseminationThe study protocol has been approved by the Nanchong Central Hospital. Written informed consent will be obtained from all the participants. The results of this study will be disseminated to the public through scientific conferences and a peer-reviewed journal.Trial registrationChiCTR, ChiCTR2100049482. Registered on 2 August 2021, http://www.chictr.org....
Source: Frontiers in Neurology - January 5, 2023 Category: Neurology Source Type: research

Stroke systems of care in the Philippines: Addressing gaps and developing strategies
In the Philippines, the mortality from stroke during the last 10 years remains high. This paper aims to describe the gaps in stroke care and the development of stroke systems of care in the Philippines. Gaps in stroke systems of care include low number of neurologist, inadequate CT scan machines, lack of stroke training among health workers, lack of stroke protocols and pathways, poor community stroke awareness, low government insurance coverage with high out of pocket medical expenses, lack of infrastructure for EMS, inadequate acute stroke ready hospitals, stroke units and rehabilitation facilities. Although there are go...
Source: Frontiers in Neurology - November 24, 2022 Category: Neurology Source Type: research