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CO33 Methodological Challenges and Considerations for Decision Makers When Assessing within-Class Comparative Effectiveness and Cost-Effectiveness: The Case of Non-Vitamin K Antagonist Oral Anticoagulants
The United Kingdom National Institute of Health Care Excellence (NICE) published a draft clinical guideline for consultation on anticoagulation therapy for stroke prevention in individuals with atrial fibrillation in September 2020 that addressed which non-vitamin K antagonist oral anticoagulant (NOAC) therapy (apixaban, dabigatran, rivaroxaban, edoxaban) is most clinically and cost-effective. We aimed to elucidate methodological considerations and challenges involved in evaluating the comparative effectiveness and cost-effectiveness of within-class treatments for the  purpose of decision making by a reimbursement authority.
Source: Value in Health - June 26, 2022 Category: International Medicine & Public Health Authors: A Briggs, A Howarth, S Davies, J Schneider, G Spentzouris, F Mughal, A Fuat, M Fay Source Type: research

A Business Case For Stroke Reduction Initiatives In Atrial Fibrillation: 3-Year Financial Projections For Three UK Regions
Atrial Fibrillation (AF) is a common and treatable risk factor for ischaemic stroke and vascular dementia with rising incidence. Oral anticoagulation (OAC) therapy is a well-evidenced way to prevent AF-related strokes, as supported by NICE Clinical Guidelines (CG180, 2014).
Source: Value in Health - October 1, 2017 Category: International Medicine & Public Health Authors: A Orlowski, T Jamieson, J Belsey, R Slater, J Macdonald Source Type: research

Feasibility Survey on Outpatient Management of Hypertension In Algeria
Hypertension (HT) is a prevalent condition, contributing risk factor to heart failure, heart attack and stroke. Ambulatory blood pressure monitoring (ABPM) is important for improving the diagnosis and management of HT as recommended by the guidelines published by the NICE in the UK in 2011. However there is a lack of data on the follow up of theses guidelines in the Maghreb countries. We aimed in this survey to assess the management of HT and usage of ABPM in daily practices in Algeria.
Source: Value in Health - April 30, 2016 Category: Global & Universal Authors: N. Hammoudi-Bendib, L. Mahi, A. Cherif, X. Girerd Source Type: research

Can Data Simulation Help Evaluate Hta Outcomes Over Time and Facilitate Early Decision-Making? a Case Study of Ticagrelor in Acute Coronary Syndrome in the Uk
In October 2011, the National Institute for Health and Care Excellence (NICE) recommended the use of ticagrelor in adult patients presenting with acute coronary syndrome (ACS) in England and Wales. The relative effectiveness and cost-effectiveness of ticagrelor compared to clopidogrel—the current standard of care in the NHS—were based on results from one large multicentre study including over 18,000 ACS patients. Patients were recruited from October 2006 through to July 2008 and primary trial data analysis, published in September 2009, demonstrated that ticagrelor significantly reduced the rate of death, myocardial inf...
Source: Value in Health - October 23, 2015 Category: Global & Universal Authors: P Dequen, NJ Cooper, K Abrams Source Type: research

The Move Towards Full Implementation Of The Nice Guidelines For Stroke Prevention In Atrial Fibrillation: The Potential Cost And Clinical Impact
Updated treatment guidelines for atrial fibrillation (AF) have been released by the National Institute for Health and Care Excellence (NICE) in the United Kingdom and highlight a current shortfall in the prescribing of anticoagulants to patients with AF despite the importance of stroke prevention. A model was designed for use as a planning tool for Clinical Commissioning Groups (CCGs) looking to budget for the future move towards full implementation of the NICE guidelines.
Source: Value in Health - November 1, 2014 Category: Global & Universal Authors: G.E. Shields, A.M. Chapman Source Type: research