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Conventional and molecular imaging in sickle cell disease
Conclusions: Central nervous system: About 25% of SCD patients are affected by vascular involvement of central nervous system. CT scan has been used to detect cerebral infarction. Subclinical cranial MRI lesions yield important predictive values as a risk factor of stroke, even when detected in asymptomatic patients. SPECT is a useful technique for early detection of deficits in cerebral perfusion in patients with SCD. Decreases in cerebral perfusions may lead to silent infarction, stroke, or neurocognitive diseases. PET may improve sensitivity in detection of impaired metabolism in the area surrounding a major vessel infa...
Source: Journal of Nuclear Medicine - May 18, 2021 Category: Nuclear Medicine Authors: Taghvaei, R., Sirous, R., Raynor, W., Amanullah, A., Werner, T., Revheim, M.-E., Hoilund-Carlsen, P. F., Alavi, A. Tags: General Clinical Specialties Source Type: research