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Cross-Reactivity as a Mechanism Linking Infections to Stroke
The relevance of infections as risk factor for cerebrovascular disease is being increasingly recognized. Nonetheless, the pathogenic link between the two entities remains poorly understood. Consistent with recent advances in medicine, the present work addresses the hypothesis that infection-induced immune responses may affect human proteins associated with stroke. Applying established procedures in bioinformatics, the pathogen antigens and the human proteins were searched for common sequences using pentapeptides as probes. The data reported demonstrate massive peptide sharing between infectious pathogens—such as Chlamydi...
Source: Frontiers in Neurology - May 13, 2019 Category: Neurology Source Type: research

Nosocomial infections after aneurysmal subarachnoid hemorrhage: time course and causative pathogens
ConclusionNosocomial infections after subarachnoid hemorrhage are common and mostly occur in the first week after ictus. Future studies should investigate if general hygienic measures, infection awareness, minimizing the duration of mechanical ventilation and use of catheters/drains, or prophylactic antibiotics reduce infections and improve functional outcome.
Source: International Journal of Stroke - April 1, 2015 Category: Neurology Authors: Kamil G. Laban, Gabriel J. E. Rinkel, Mervyn D. I. Vergouwen Tags: Research Source Type: research