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Source: Journal of Neurology, Neurosurgery and Psychiatry
Infectious Disease: Botulism

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Pharyngeal-cervical-brachial variant of Guillain-Barre syndrome
The pharyngeal-cervical-brachial (PCB) variant of Guillain–Barré syndrome is defined by rapidly progressive oropharyngeal and cervicobrachial weakness associated with areflexia in the upper limbs. Serial nerve conduction studies suggest that PCB represents a localised subtype of Guillain–Barré syndrome characterised by axonal rather than demyelinating neuropathy. Many neurologists are unfamiliar with PCB, which is often misdiagnosed as brainstem stroke, myasthenia gravis or botulism. The presence of additional ophthalmoplegia and ataxia indicates overlap with Fisher syndrome. Half of patients with...
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 6, 2014 Category: Neurosurgery Authors: Wakerley, B. R., Yuki, N. Tags: Editor's choice, Immunology (including allergy), Cranial nerves, Drugs: CNS (not psychiatric), Neuromuscular disease, Stroke, Ophthalmology Source Type: research