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Source: Neurological Research
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Total 381 results found since Jan 2013.

Health-related quality of life after ischemic stroke: impact of sociodemographic and clinical factors
CONCLUSION: Stroke survivors have significantly reduced HR-QoL. Multiple interacting factors are associated with an unfavorable outcome after IS. Early detection of these factors would help to improve the care for IS patients, to reduce disabilities and improve HR-QoL.PMID:33637026 | DOI:10.1080/01616412.2021.1893563
Source: Neurological Research - February 27, 2021 Category: Neurology Authors: M Tsalta-Mladenov S Andonova Source Type: research

The association between White matter microstructure alterations detected by Diffusional kurtosis imaging in Neural circuit and post-stroke depression.
CONCLUSION: Our research indicated that the damage to WM microstructure in the frontal lobe, temporal lobe and the genu of corpus callosum may be related toPSD. DKI explores the microstructural changes of WM in PSD patients and may be an auxiliary diagnostic method for PSD. PMID: 33588692 [PubMed - as supplied by publisher]
Source: Neurological Research - February 17, 2021 Category: Neurology Tags: Neurol Res Source Type: research

Vitality index is a predictor of the improvement in the functional independence measure score in subacute stroke patients with cognitive impairment.
DISCUSSION: The vitality index was significantly associated with FIM improvement in subacute stroke patients with cognitive impairment. PMID: 33497321 [PubMed - in process]
Source: Neurological Research - January 28, 2021 Category: Neurology Tags: Neurol Res Source Type: research

Acute and long-term impairments regarding emotional symptoms and quality of life in patients suffering from transient ischemic attack and stroke.
This study follows the hypothesis that TIA patients might exhibit non-physical symptoms affecting individual QoL. Methods: In a prospective single-center observational study, IS patients (n = 73) were compared with TIA patients (n = 24) regarding their neurological deficit, ES and QoL, whereas the latter were evaluated by the Hospital Anxiety and Depression Scale (HADS) and the Short Form 36 Heath Survey (SF-36). Assessments were conducted six times within a one-year follow-up period. Results: Overall, anxiety and depression decreased over time, while anxiety decreased more substantially. TIA patients showed similar le...
Source: Neurological Research - January 24, 2021 Category: Neurology Tags: Neurol Res Source Type: research

Association between insulin resistance and aspirin or clopidogrel resistance in Chinese patients with recent ischemic stroke/TIA.
Conclusions: Insulin resistance was an independent predictor for development of antiplatelet drug resistance in patients with recent minor ischemic stroke or TIA. More attention should be paid to recognize these patients and antithrombotic effect should be monitored when antiplatelet drugs were applied to these patients. PMID: 33455562 [PubMed - as supplied by publisher]
Source: Neurological Research - January 21, 2021 Category: Neurology Tags: Neurol Res Source Type: research

Application of the P300 potential in cognitive impairment assessments after transient ischemic attack or minor stroke.
Conclusions The P300 latency delay can be used to detect cognitive impairments in patients after TIA/minor stroke and the P300-Fz latency is more sensitive for diagnosing cognitiveimpairments in TIA/minor stroke patients. PMID: 33443462 [PubMed - as supplied by publisher]
Source: Neurological Research - January 15, 2021 Category: Neurology Tags: Neurol Res Source Type: research

Association of inflammatory and platelet volume markers with clinical outcome in patients with anterior circulation ischaemic stroke after endovascular thrombectomy.
Conclusions: MPV, PDW, and MPV/PC are associated with stroke severity. Higher NLR levels upon admission may predict unfavorable functional outcomes in patients with AIS after undergoing EVT.Abbreviations ACA: anterior cerebral artery; AIS: acute ischemic stroke; ASPECTS: alberta stroke program early CT score; BMI: body mass index; DBP: diastolic blood pressure; END: early neurological deterioration; EVT: endovascular thrombectomy; hs-CRP: high-sensitivity C-reactive protein; HT: hemorrhagic transformation; ICA: internal carotid artery; IL-6: interleukin-6; IS: ischemic progression; LAA: Large-Artery Atherosclerosis; MCA: m...
Source: Neurological Research - January 8, 2021 Category: Neurology Tags: Neurol Res Source Type: research

Impact of shoulder subluxation on peripheral nerve conduction and function of hemiplegic upper extremity in stroke patients: A retrospective, matched-pair study.
Conclusions: Stroke may lead to extensive abnormal nerve conduction on the HUE, and SS may aggravate the abnormality, which may disturb the recovery of upper limb function. PMID: 33402052 [PubMed - as supplied by publisher]
Source: Neurological Research - January 8, 2021 Category: Neurology Tags: Neurol Res Source Type: research

Risk factors for in-hospital mortality among acute ischemic stroke patients in China: a nationwide prospective study.
Conclusions: The findings from this study may help clinicians control the risk of IHM better for patients with AIS. PMID: 33357098 [PubMed - as supplied by publisher]
Source: Neurological Research - December 29, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Tirofiban combined with heparin's effect and safety in the treatment of mild to moderate acute ischemic stroke.
Authors: Qiu T, Li C, Huang L, Xiao H, Deng X, Dai X, Fu S, Wang J, Gong Q, Luo Q, Wang M, He W, Chen M Abstract Tirofiban can be used to treat patients with acute ischemic stroke (AIS), this study was to evaluate the efficacy and safety of tirofiban combined with heparin in the treatment of mild to moderate AIS. A total of 98 patients with mild to moderate AIS randomly were divided into 2 groups within 48 h: the treatment group treated with tirofiban and, and the control group treated with aspirin + clopidogrel. The treatment group was given the same scheme as the control group after the treatment of tirofiban co...
Source: Neurological Research - December 6, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Evaluating the effect of transplanting umbilical cord matrix stem cells on ischemic tolerance in an animal model of stroke.
CONCLUSION: The pretreatment of the transplanted umbilical cord stem cells in the striatum of ischemic rats possibly leads to restorative events, exerting a decreasing effect on cell death. Subsequently, these events may improve the motor ability and reduce ischemic injuries. PMID: 33167823 [PubMed - as supplied by publisher]
Source: Neurological Research - November 12, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Screening for cognitive impairment with the montreal cognitive assessment at six months after stroke and transient ischemic attack.
CONCLUSION: The MoCA-Beijing cutoff score for differentiating CI from NCI after stroke and TIA at six months was at 24/25, and it is important for routine clinical practice. PMID: 32967577 [PubMed - as supplied by publisher]
Source: Neurological Research - September 26, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Predictors, causes and outcome of 30-day readmission among acute ischemic stroke.
CONCLUSIONS: Older age, stroke severity, prior stroke, diabetes, indwelling urinary catheter and admission to non-neurology floor during index admission were associated with 30-day readmission. 30-readmission after AIS increased hospitalization expenses, LOS and in-hospital mortality. PMID: 32893753 [PubMed - as supplied by publisher]
Source: Neurological Research - September 9, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Relationship between methylenetetrahydrofolate reductase (MTHFR) gene (A1298C) polymorphism with the risk of stroke: A systematic review and meta-analysis.
Authors: Kumar A, Sharma R, Misra S, Nath M, Kumar P Abstract Studies on relationship between methylenetetrahydrofolate reductase gene (MTHFR) gene A1298C polymorphism with the risk of ischemic as well as hemorrhagic stroke have shown discordant results. Present meta-analysis was aimed to clarify the relationship between MTHFR gene A1298C polymorphism with risk of stroke. A comprehensive literature search for all published articles was performed in electronic database including PubMed, EMbase, Cochrane Library, Trip Databases, Worldwide Science, CINAHL, and Google Scholar up to 31st  December 2019. Pooled odds r...
Source: Neurological Research - August 1, 2020 Category: Neurology Tags: Neurol Res Source Type: research