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Association study of CACNA1C polymorphisms with large artery atherosclerotic stroke in Chinese Han population.
Conclusion The results suggested that there was a potential association between CNCNA1C gene and the risk factor of LAA stroke in Chinese Han population. PMID: 29683785 [PubMed - as supplied by publisher]
Source: Neurological Research - April 24, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Effect of renal function on association between uric acid and prognosis in acute ischemic stroke patients with elevated systolic blood pressure.
CONCLUSION: The present study suggests that high serum uric acid concentration is associated with better prognosis in ischemic stroke patients with normal renal function, but not in those with abnormal renal function. The establishment of causality between increased uric acid levels and better stroke prognosis needs more suitably designed randomized clinical trials. PMID: 32657261 [PubMed - as supplied by publisher]
Source: Neurological Research - July 15, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Serum leptin is associated with first-ever ischemic stroke, lesion size and stroke severity in a Chinese cohort.
CONCLUSION: Serum leptin is associated with first-ever AIS, lesion size and stroke severity in a Chinese cohort. PMID: 30433860 [PubMed - as supplied by publisher]
Source: Neurological Research - November 17, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Association of hemoglobin glycation index with outcomes of acute ischemic stroke in type 2 diabetic patients.
Conclusion Both low HGI and high HGI was associated with an increased risk of poor prognosis in diabetic patients with ischemic stroke, compared with moderate HGI. PMID: 29560815 [PubMed - as supplied by publisher]
Source: Neurological Research - March 23, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Lp-PLA2 as a risk factor of early neurological deterioration in acute ischemic stroke with TOAST type of large arterial atherosclerosis.
Authors: Wang Y, Hu S, Ren L, Lei Z, Lan T, Cai J, Li C Abstract INTRODUCTION: Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a well-known risk factor of atherosclerotic vascular diseases. Nevertheless, its role in the acute phase of ischemic stroke is still unclear. The aim of this study is to identify the relationship between Lp-PLA2 levels and early neurological deterioration (END) in acute ischemic stroke patients with Trial of Org 10 172 in Acute Stroke Treatment (TOAST) subtype of large arterial atherosclerosis (LAA). METHODS: We enrolled Chinese patients with first ever acute ischemic stroke admitt...
Source: Neurological Research - October 10, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Elevated levels of total homocysteine after ischemic stroke: a potential marker for in-hospital outcomes
CONCLUSION: HHcy was associated with increased in-hospital stroke recurrence and CVD events among patients with IS. In low-folate regions, tHcy levels may potentially predict in-hospital outcomes after IS.PMID:36893016 | DOI:10.1080/01616412.2022.2159137
Source: Neurological Research - March 9, 2023 Category: Neurology Authors: Wei Liu Xue-Lian Ma Hong-Qiu Gu Hao Li Zi-Xiao Li Yong-Jun Wang Source Type: research

Elevated CRP at admission predicts post-stroke cognitive impairment in Han Chinese patients with intracranial arterial stenosis.
CONCLUSIONS: To our knowledge, this is the first study to explore the effects of CRP on PSCI in Han Chinese with ICAS. Our findings indicate that higher CRP levels at admission are associated with subsequent cognitive decline in Han Chinese patients with ICAS following ischemic stroke. Further studies in other ethnic groups are needed to validate the use of CRP to predict dementia in ICAS patients. PMID: 29451096 [PubMed - as supplied by publisher]
Source: Neurological Research - February 18, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Development and validation of a risk score to predict 30-day mortality in patients with atrial fibrillation-related stroke: GPS-GF score.
Conclusion The GPS-GF score is a simple and valid tool for predicting 30-day mortality in patients with AF-related stroke. PMID: 29544401 [PubMed - as supplied by publisher]
Source: Neurological Research - March 20, 2018 Category: Neurology Tags: Neurol Res Source Type: research

The effect of intravenous ginkgolide on clinical improvement of patients with acute ischemic stroke.
Conclusion: Intravenous ginkgolide may improve the outcome of acute ischemic stroke. Differences in effect between pre-marketing and post-marketing studies may be associated with gender, time of onset to enrollment and severity of stroke. PMID: 32048567 [PubMed - as supplied by publisher]
Source: Neurological Research - February 13, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Management of endovascular therapy for acute ischemic stroke amid the COVID-2019 pandemic: a multicenter survey in China
Conclusions: The volume of EVT for acute ischemic stroke severely declined after lockdown in China. Designating a specific area for COVID-19 screening, insufficient personal protection and understaffing may exacerbate the volume decline of EVT.PMID:34375569 | DOI:10.1080/01616412.2021.1939236
Source: Neurological Research - August 10, 2021 Category: Neurology Authors: Guangge Peng Ximing Nie David Liebeskind Liping Liu Zhongrong Miao Source Type: research

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