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Source: Expert Review of Cardiovascular Therapy

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Total 135 results found since Jan 2013.

Response to letter: 'Bear tracks hypothesis: from atrial fibrillation to atrial fibrosis syndrome in stroke risk assessment'.
Authors: O'Neill L, Harrison J, O'Neill M, Williams SE PMID: 28699363 [PubMed - as supplied by publisher]
Source: Expert Review of Cardiovascular Therapy - July 13, 2017 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Bear tracks hypothesis: from atrial fibrillation to atrial fibrosis syndrome in stroke risk assessment.
Authors: Ozeke O, Cay S, Ozcan F, Hacili A, Topaloglu S, Aras D PMID: 28697653 [PubMed - as supplied by publisher]
Source: Expert Review of Cardiovascular Therapy - July 13, 2017 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Premature atrial complexes in an ischemic stroke population and risk of recurrent stroke: a systematic review.
Authors: Sejr MH, Riahi S, Larsen TB, Nielsen JC, Nielsen PB Abstract INTRODUCTION: Premature atrial complexes (PACs) have been proposed as a possible mediator between normal sinus rhythm and atrial fibrillation (AF). The aim of this study was to summarize the available knowledge of association between PACs and recurrent stroke or transient ischemic attack (TIA) in ischemic stroke patients. Areas covered: In this systematic review, we investigated the risk of recurrent events in patients who experienced ischemic stroke or TIA. Occurrence of PACs in electrocardiographic monitoring after index stroke/TIA was required...
Source: Expert Review of Cardiovascular Therapy - May 24, 2017 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Achieving blood pressure targets for prolonged cardiovascular health: a historical perspective.
Authors: Chrysant SG Abstract INTRODUCTION: Hypertension is a major risk factor for coronary artery disease (CAD), stroke, heart failure, and chronic kidney disease (CKD), and its successful control leads to a decrease or prevention of these complications. Areas covered: Over the years the Joint National Committees and the American Heart Association have issued guidelines regarding the treatment of hypertension. Those of 2003 and 2007 respectively, have recommended reduction of blood pressure (BP) to < 140/90 mmHg for uncomplicated hypertension and to < 130/80 mmHg for hypertensive patients with diabetes mell...
Source: Expert Review of Cardiovascular Therapy - May 8, 2017 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Rivaroxaban in patients with atrial fibrillation: from ROCKET AF to everyday practice.
Authors: Barón-Esquivias G, Marín F, Sanmartín M Abstract INTRODUCTION: Registries and non-interventional studies offer relevant and complementary information to clinical trials, since they have a high external validity. Areas covered: The information regarding the efficacy and safety of rivaroxaban compared with warfarin, or rivaroxaban alone in clinical practice was reviewed in this manuscript. For this purpose, a search on MEDLINE and EMBASE databases was performed. The MEDLINE and EMBASE search included both medical subject headings (MeSH) and keywords including: atrial fibrillation (AF) OR warfarin OR clini...
Source: Expert Review of Cardiovascular Therapy - March 21, 2017 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Ischemic Stroke Risk in East Asian patients with CHA2DS2-VASc Score of 1: Systematic Review and Meta-analysis.
Conclusions Some regional differences between East Asian countries were observed for ischemic stroke risk in patients with a CHA2DS2-VASc score of 1. This may reflect methodological differences in studies, but further prospective studies are required to ascertain ischemic stroke risks, as well as the differences and reasons for this between East Asians and non-East Asians. PMID: 28076988 [PubMed - as supplied by publisher]
Source: Expert Review of Cardiovascular Therapy - January 13, 2017 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Multimodality ultrasound imaging in stroke: current concepts and future focus.
We present the conventional ultrasonography as well as the novel ultrasound techniques including gray scale median, 3-dementional ultrasound, elastography, intravascular ultrasound, and contrast-enhanced ultrasound. Expert commentary: Ultrasonography is a non-invasive, low-cost, safe, fast, and real-time imaging technology for stroke risk assessment. Each modality has its own advantage as well as limitation. Future research should be focused on developing new technologies that can improve the quality of imaging and accuracy of diagnosis. PMID: 27785921 [PubMed - as supplied by publisher]
Source: Expert Review of Cardiovascular Therapy - October 29, 2016 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

To close or not to close: contemporary indications for patent foramen ovale closure.
Authors: Zier LS, Sievert H, Mahadevan VS Abstract INTRODUCTION: Patent foramen ovale (PFO) is a common congenital cardiac abnormality and that has been associated with several disease processes including transient ischemic attacks (TIA), stroke, migraine headaches with aura, decompression sickness, platypnea-orthodeoxia syndrome, and shunt induced cyanosis. Controversy exists regarding closure of PFO as a therapeutic treatment modality for these disease processes. This review addresses the contemporary clinical indications for PFO closure. AREAS COVERED: We conducted a comprehensive literature search of contem...
Source: Expert Review of Cardiovascular Therapy - September 14, 2016 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Imaging in acute stroke.
Authors: Eswaradass P, Appireddy R, Evans J, Tham C, Dey S, Najm M, Menon BK Abstract INTRODUCTION: Stroke is the third leading cause of death and disability in Canada. In the hyperacute stroke setting, the treating physician must make a time critical decision on the treatment of each patient. Recent advances in imaging help the treating physician identify the subgroup of patients eligible for acute treatment of ischaemic stroke. AREAS COVERED: In this review we will discuss Non-Contrast Computed Tomography (NCCT), CT-Angiography (CTA), and CT-Perfusion (CTP) in assessment of patients with acute ischaemic strok...
Source: Expert Review of Cardiovascular Therapy - June 3, 2016 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Extended-release acetylsalicylic acid for secondary prevention of stroke and cardiovascular events.
Authors: Bliden KP, Tantry US, Chaudhary R, Byun S, Gurbel PA Abstract Aspirin has been the bedrock of antiplatelet treatment strategies for the secondary prevention of recurrent cardiovascular and cerebrovascular events for the last 3 decades. The limitations of standard aspirin therapy include bleeding, gastrotoxicity, and loss of antiplatelet effect over a 24-hour period in selected high-risk patients. An extended-release aspirin formulation, Durlaza(®) (New Haven Pharmaceuticals, Inc., North Haven, CT), has been developed to address some of the latter limitations and may provide an alternative to standard aspi...
Source: Expert Review of Cardiovascular Therapy - May 25, 2016 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Epidemiology of left ventricular hypertrophy in hypertension: Implications for the clinic.
Authors: Cramariuc D, Gerdts E Abstract Left ventricular hypertrophy (LVH) is a common complication to hypertension, indicating the presence of hypertensive heart disease, which puts the patient at a very high risk for subsequent clinical cardiovascular events like sudden cardiac death, stroke, myocardial infarction and heart failure. The epidemiology of LVH has changed in recent years as a consequence of the development of new diagnostic tools and demographic changes in hypertensive populations. In individual hypertensive patients, the presence and type of LVH and associated systolic and diastolic myocardial dysfu...
Source: Expert Review of Cardiovascular Therapy - May 10, 2016 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Lifestyle management to prevent and treat atrial fibrillation.
Authors: Gallagher C, Hendriks JM, Mahajan R, Middeldorp ME, Elliott AD, Pathak RK, Sanders P, Lau DH Abstract Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia with a one in four lifetime risk in adults over the age of forty. Traditionally, AF management has focused on the three pillars of rate control, rhythm control and appropriate anticoagulation to reduce stroke risk. More recently, the importance of cardiovascular risk factor management in AF has emerged as a fourth and essential pillar with evidence suggesting that an optimal cardiovascular risk factor profile is associated with improv...
Source: Expert Review of Cardiovascular Therapy - April 28, 2016 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Atrial fibrillation management: evaluating rate vs rhythm control.
Authors: Nguyen T, Jolly U, Sidhu K, Yee R, Leong-Sit P Abstract Atrial fibrillation (AF) is an increasing global issue leading to increased hospitalizations, adverse health related events and mortality. This review focuses on the management of atrial fibrillation, in particular in the past decade, comparing two major strategies, rate or rhythm control. We evaluate the evidence for each strategy, pharmacological options and the increasing utilization of invasive techniques, in particular catheter ablation and use of implantable cardiac pacing devices. Pharmacological comparative trials evaluating both strategies ha...
Source: Expert Review of Cardiovascular Therapy - March 11, 2016 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Asymptomatic atrial fibrillation burden and thromboembolic events: piecing evidence together.
CONCLUSION: A direct correlation between burden of asymptomatic AF and HR for stroke cannot be detected in our pooled analysis. However, due to the limitations acknowledged in the analysis, our findings need to be confirmed in large cohort studies. PMID: 26894263 [PubMed - as supplied by publisher]
Source: Expert Review of Cardiovascular Therapy - February 20, 2016 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Should uric acid be administered alongside thrombolysis for stroke patients?
Authors: Amaro S, Chamorro Á PMID: 26788663 [PubMed - as supplied by publisher]
Source: Expert Review of Cardiovascular Therapy - February 17, 2016 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research