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P114/135 Drug-coated balloons for treatment of in-stent restenosis following carotid artery stenting: a major case, single center study
ConclusionIn our practice, DCB offers a straightforward option to treat restenosis of the ACI ostium. The low rate of periprocedural complications and the median time of freedom from symptoms and/or restenosis suggest that DCB angioplasty for ISRS is a viable treatment.Disclosure of InterestNothing to disclose
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Hajiyev, K., Gottberg, P. v., Henkes, H. Tags: 3.1 OTHER - Innovation Source Type: research

E-115 Trans-radial versus trans-femoral access routes for diagnostic cerebral angiograms: a large single-center comparative cost-analysis study
ConclusionOverall, our study shows that the TR approach can be less a less expensive option for patients undergoing diagnostic cerebral angiograms, especially if complications occur. Future studies can corroborate our findings and potentially lead to the adoption of TR as a low-cost, efficient, gold-standard technique for cerebral angiography.Costs (dollars) Associated with Trans-Radial Versus Trans-Femoral AccessAbstract E-115 Table 1 Variable Trans-Femoral (n=314) Trans-Radial(n=612) P-value Total Cost, mean (SD) 12591.8 (19128) 12789.5 (18424) .88 Catheters, median (range) 12.4 (12.4-1900) 55.2 (12.4-369) .03 Closure d...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: El Naamani, K., Atallah, E., Momin, A., Jain, P., Hunt, A., Sambangi, A., Carreras, A., El Fadel, O., Gooch, M., Tjoumakaris, S., Zarzour, H., Schmidt, R., Herial, N., Rosenwasser, R., Jabbour, P. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

O-007 Bridging thrombolysis yields diminished benefit among elderly stroke patients treated with endovascular thrombectomy
ConclusionsBridging thrombolysis may be associated with better outcomes in a real-world setting; however, this association is diminished among elderly patients due to higher rates of hemorrhagic complications. Meta-analyses of trial data and future prospective studies are needed to fully elucidate the benefits and risks of bridging thrombolysis in the elderly population.Abstract O-007 Figure 1Disclosures H. Chen: None. M. Khunte: None. M. Colasurdo: None. A. Malhotra: None. D. Gandhi: 1; C; National Institutes of Health, Focused Ultrasound Foundation, MicroVention, University of Calgary, University of Maryland Medical Center.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Chen, H., Khunte, M., Colasurdo, M., Malhotra, A., Gandhi, D. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

P-005 Predictors for large vessel recanalization before stroke thrombectomy
ConclusionsIVT at least 1.5 hours before angiography, site of vascular occlusion, atrial fibrillation, and hyperlipidemia are independent predictors for LVR. The 8-point Recan score proposed in this study may be a valuable tool for predicting LVR before EVT.Abstract P-005 Figure 1Disclosures H. Chen: None. M. Colasurdo: None. C. Schrier: None. M. Khalid: None. M. Khunte: None. T. Miller: None. J. Cherian: None. A. Malhotra: None. D. Gandhi: 1; C; National Institutes of Health, Focused Ultrasound Foundation, MicroVention, University of Calgary, University of Maryland Medical Center.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Chen, H., Colasurdo, M., Schrier, C., Khalid, M., Khunte, M., Miller, T., Cherian, J., Malhotra, A., Gandhi, D. Tags: SNIS 20th annual meeting oral poster abstracts Source Type: research

P-023 Initial experience with transcranial ultrasound through sonolucent cranioplasty after hemicraniectomy for ischemic and hemorrhagic stroke
ConclusionTranscranial ultrasound through large, customized sonolucent cranioplasty is safe and feasible after decompressive hemicraniectomy. This imaging technique may alleviate the cost, transport, and radiation burden of CT in select ICH patients.Abstract P-023 Figure 1Disclosures C. Rossitto: None. H. Tabani: None. A. Reynolds: None. C. Kellner: 1; C; CPK receives research funding from Longeviti Neuro Solutions, Penumbra, Integra, Viz.AI, Minnetronix, Siemens, and Cerebrotech.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Rossitto, C., Tabani, H., Reynolds, A., Kellner, C. Tags: SNIS 20th annual meeting oral poster abstracts Source Type: research

P56 Safety and efficacy of trans-carotid intervention in multiple scenarios: medellin experience using direct carotid access
ConclusionTrans Carotid Interventionwas feasible and safe in selected patients in this small series.ReferencesYan Chan JC, Edward Chu Yi, Wei Cheung IH, On Tsang AC, Lau KK, Lee R. Direct carotid puncture for mechanical thrombectomy in acute ischemic stroke: literature review and a single-center experience. World Neurosurg 2022 Mar 31:S1878–8750(22)00410–7. DOI: 10.1016/J.WNEU.2022.03.115. EPUB AHEAD of Print. PMID: 35367393.Abe T, Sakata H, Ezura M, Endo H, Tominaga T. Direct carotid puncture for endovascular surgery of intracranial aneurysms: technical note for avoiding complications. Surg Neurol Int 2022 Feb...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Torres, V., Pabon, B., Patino, M., Pelaez, F., Mutis, J. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

E-077 Carotid ultrasound findings and stenosis severity at enrollment in CREST 2
ConclusionThe CREST-2 eligibility criteria were specified to recruit individuals with a high degree of stenosis. However, even within this group of patients with a (likely) high degree of stenosis, there was a surprising heterogeneity between patients in the pattern of flows that qualified for the study, introducing the opportunity to assess differential treatment effects between those with different patterns.Disclosures D. Heck: 2; C; Stryker. G. Roubin: 2; C; Consultant for Inspire MD Inc, Contego Medical, Cook Inc. W. Moore: None. G. Howard: None. J. Meschia: None. R. Brown: None. T. Brott: None. B. Lal: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Heck, D., Roubin, G., Moore, W., Howard, G., Meschia, J., Brown, R., Brott, T., Lal, B. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-142 Robotic transcranial doppler with artificial intelligence to identify cerebral emboli during transcatheter aortic valve replacement - a novel neuromonitoring tool
ConclusionIn this study, we report our experience using a Robotic Transcranial Doppler (TCD) with Artificial Intelligence as a novel real-time intraoperative neuromonitoring tool in patients undergoing TAVR. By reporting quantity and distribution of high intensity transient signals (HITS) as markers of microemboli during the procedure, we report significantly lower HITS using sentinel cerebral protection. We also identify valve positioning and implantation as the most significant stage in terms of HITS during the procedure.Abstract E-142 Table 1Emboli HITS during critical phases of the procedure Procedure Stage With Cere...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Baig, A., Manion, C., Iyer, V., Khawar, W., Donnelly, B., Monteiro, A., Levy, E., Siddiqui, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

O-027 Intra-arterial delivery of autologous mitochondria for ischemic stroke
Mitochondria are cellular powerhouses responsible for maintenance of homeostasis. Dysfunction of this cellular component has been associated with secondary injury after ischemic stroke. We postulated that autologous mitochondrial delivery via an intra-arterial route would mitigate injury caused by cerebral ischemia in a model resembling large vessel occlusion and revascularization.We used biochemical methods to purify autologous mitochondria from a single punch biopsy of skeletal muscle. The mitochondria were assayed for biological activity. Using mouse models of cerebral ischemia and reperfusion, we delivered viable mitoc...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Kalani, Y., Norat, P., Tvrdik, P., Levitt, M., Walker, M. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

E-184 Transradial approach for pediatric diagnostic and neurointerventional surgery: single center case series and systematic review
ConclusionsOur results and the literature review demonstrate that the TRA is a safe and feasible option for pediatric patients. Routine use of ultrasound guidance, selection of appropriately sized catheters, and prophylactic use of vasodilators and antispasmodics can help ensure the success of the procedure and limit common access-site complications.Disclosures A. Baig: None. J. Neumaier: None. Y. Hashmi: None. A. Monteiro: None. M. Waqas: None. J. Cappuzzo: None. W. Khawar: None. K. Snyder: 2; C; Canon Medical Systems Corporation, Penumbra Inc., Medtronic, and Jacobs Institute. 4; C; : Boston Scientific, Access Closure In...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Baig, A., Neumaier, J., Hashmi, Y., Monteiro, A., Waqas, M., Cappuzzo, J., Khawar, W., Snyder, K., Levy, E., Siddiqui, A., Reynolds, R., Davies, J. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Drug-coated balloon for vertebral artery origin stenosis: a pilot study
Conclusion This pilot study suggests that DCB is a safe approach for VAOS. The relatively low restenosis rate indicates the its potential long-term efficacy for VAOS. Future randomized controlled trials to confirm its efficacy are warranted.
Source: Journal of NeuroInterventional Surgery - August 13, 2021 Category: Neurosurgery Authors: Wang, Y., Feng, Y., Wang, T., Ma, Y., Gao, P., Chen, J., Chen, Y., Yang, B., Jiao, L. Tags: Ischemic stroke Source Type: research

E-004 Focal intracranial vasculopathy as a manifestation of COVID-19-associated acute ischemic stroke
ConclusionTo our knowledge, our case is the first to illustrate the potential for COVID-19 infection to present as a focal intracranial vasculopathy in an otherwise healthy young-patient, resulting in acute ischemic stroke without an underlying hypercoagulable state. Rescue intracranial stenting was necessary to maintain vessel patency and restore intracranial flow.Disclosures A. Mahapatra: None. A. Witek: None. G. Toth: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Mahapatra, A., Witek, A., Toth, G. Tags: Electronic poster abstracts Source Type: research

E-021 Safety and efficacy of a low dose eptifibatide infusion during endovascular treatment of tandem occlusions
Conclusions The low dose eptifibatide infusion resulted in a low incidence of SICH (5%) in the endovascular treatment of tandem intracranial occlusions. The infusion was not potent enough to maintain patency of the carotid artery in all patients. However, re-occlusion of the carotid artery was asymptomatic in the 4 patients where it occurred. This underscores that extracranial re-occlusion of the carotid artery is the lesser of evils compared with hemorrhagic stroke conversion. Limitations of the study include retrospective data collection, a low incidence of intravenous t-PA use, and lack of independent adjudication of an...
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Roels, C., Brown, M., Janjua, R., Heck, D. Tags: Electronic Poster Abstracts Source Type: research

The modified 'no touch technique in the antegrade endovascular approach for left common carotid artery ostial stenosis stenting
Conclusions The modified ‘no touch’ antegrade endovascular technique is a feasible method for treating LCCA ostial lesions with a satisfactory initial success rate, acceptable procedure time, and comparable mid- and long-term results. This technique could be considered as a complementary option for LCCA ostial stenosis in addition to open surgery and the retrograde endovascular approach.
Source: Journal of NeuroInterventional Surgery - January 12, 2017 Category: Neurosurgery Authors: Tang, X., Long, W. A., Hu, C., Tang, F., Wang, Q., Li, L., Qiu, Sun Tags: Ischemic stroke Source Type: research

O-012 Emergent Endovascular Management of Long-segment Carotid Artery Dissections in Acute Ischemic Stroke Intervention with Multiple Tandem Stents
ConclusionTandem stent reconstruction for the treatment of long segment and flow limiting carotid dissections is technically safe and effective with favorable clinical outcomes in acute ischemic stroke intervention, allowing for successful thrombectomy, vessel salvage, restoration of cerebral perfusion, and prevention of recurrent thromboembolic stroke.DisclosuresS. Ansari: None. A. Kuhn: None. A. Honarmand: None. S. Hou: None. M. Khan: None. J. Chueh: None. I. van der Bom: None. M. Hurley: None. A. Shaibani: None. M. Gounis: None. M. Potts: None. B. Jahromi: None. A. Wakhloo: None. A. Puri: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Ansari, S., Kuhn, A., Honarmand, A., Hou, S., Khan, M., Chueh, J., Bom, I. v. d., Hurley, M., Shaibani, A., Gounis, M., Potts, M., Jahromi, B., Wakhloo, A., Puri, A. Tags: Oral abstracts Source Type: research

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