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E-036 age, stroke severity, use of stent retrievers, general anesthesia, and hemorrhagic conversion may predict outcome in stroke patients who undergo successful intra-arterial therapy
ConclusionAge, NIHSS score, use of stent retrievers, mode of anesthesia, and symptomatic ICH might affect functional outcome in stroke patients who achieve successful recanalization via intra-arterial therapy. Prospective studies, or a meta-analysis of sub-groups in the recently published prospective trials are needed to confirm the association between those factors, or others, and functional outcome. Identification of such predictors might help in screening acute stroke patients for intra-arterial therapy.DisclosuresM. Noufal: None. J. Mankad: None. D. Shirilla: None. A. Lakraj: None. J. Cox: None. A. Sattar: None. W. Wal...
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Noufal, M., Mankad, J., Shirilla, D., Lakraj, A., Cox, J., Sattar, A., Wally, W., Sallowm, Y., Lynch, J., Zaidat, O. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

E-062 transradial access for acute interventional stroke therapy
ConclusionTransradial artery access for neuro-interventional procedures is rarely considered today. Our small case study suggests that transradial access is safe and efficacious in advance stroke therapy. Further studies with larger sample size are needed.DisclosuresJ. Farkas: None. K. Sivakumar: None. T. Sabharwal: None. H. Dababneh: None. A. Tiwari: None. K. Arcot: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Farkas, J., Sivakumar, K., Sabharwal, T., Dababneh, H., Tiwari, A., Arcot, K. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

E-129 nihss assessment during the stroke hospitalization is a significant predictor of 90-day functional outcome in the natural history of acute ischemic stroke from large vessel occlusion
ConclusionNIHSS at 24 h and at 7 days or discharge had a strong correlation with 90-day functional outcome. This study provides invaluable information for stroke physicians to be able to prognosticate when they talk to patients and family members at the end of hospitalization. In addition, this landmark study will help recruitment and completion of future medical device trials on stroke patients much faster and cost-effectively, thereby bringing down healthcare costs and facilitating newer medical devices for stroke treatment to become available to patients sooner.Abstract E-129 Table 1Correlation between ASPECTS and NIHSS...
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Janardhan, V., Shams, T., Yoo, A., Frei, D., Patel, K., Gianatasio, R., Venizelos, A., Ammar, L., Kuo, S., Hak, S., Nguyen, N., Buell, H., Barraza, L., Bose, A., Sit, S. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

The association between carotid intraplaque hemorrhage and outcomes of carotid stenting: a systematic review and meta-analysis
Conclusions Our systematic review and meta-analysis demonstrated that patients with IPH on pre-carotid stenting MRI had higher rates of silent ischemia as well as of a composite outcome of perioperative stroke, death, and MI compared with those without IPH.
Source: Journal of NeuroInterventional Surgery - August 17, 2017 Category: Neurosurgery Authors: Brinjikji, W., Lehman, V. T., Huston, J., Murad, M. H., Lanzino, G., Cloft, H. J., Kallmes, D. F. Tags: Ischemic stroke Source Type: research

Long term durability and outcomes of carotid stenting and carotid endarterectomy
Conclusions Although CAS may be more strongly associated with periprocedural stroke/death compared with CEA, it could be a good alternative to CEA in terms of long term durability and outcomes.
Source: Journal of NeuroInterventional Surgery - July 12, 2017 Category: Neurosurgery Authors: Jung, J.-M., Choi, J.-Y., Kim, H. J., Suh, S.-i., Seo, W.-K. Tags: Ischemic stroke Source Type: research

E-033 The smoking-thrombolysis paradox in large vessel occlusion acute ischemic stroke after endovascular therapy
Conclusion In stroke patients treated with mechanical thrombectomy, smoking does not seem to be associated with outcomes regardless of stroke subtype or location. Disclosures J. Grossberg: None. M. Bouslama: None. L. Rebello: None. D. Haussen: None. M. Frankel: None. R. Nogueira: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Grossberg, J., Bouslama, M., Rebello, L., Haussen, D., Frankel, M., Nogueira, R. Tags: Electronic Poster Abstracts Source Type: research

O-020 Novel cone beam CT technology improves image quality for stroke assessment: a prospective series
ConclusionsThe latest generation of CB-CT scans & technology allow for exclusion of haemorrhages, stroke core definition and demonstration of brain perfusion and collaterals. These improvements suggest that CB-CT is acceptable for emergency stroke imaging assessment before mechanical thrombectomy, which may reduce door-to-groin puncture times and improve patient outcomes.ReferenceBourcier R, Goyal M, Liebeskind DS, et al. Association of time from stroke onset to groin puncture with quality of reperfusion after mechanical thrombectomy: a meta-analysis of individual patient data from 7 randomized clinical trials. JAMA Ne...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Cancelliere, N., Nicholson, P., Nijnatten, F., Hummel, E., Withagen, P., van de Haar, P., Agid, R., Hallacoglu, B., van Vlimmeren, M., Mendes Pereira, V. Tags: Oral abstracts Source Type: research

E-074 Predictors of hemorrhagic conversion following mechanical thrombectomy for acute ischemic stroke (AIS)
ConclusionHistory of prior stroke, radiographic evidence of infarct burden, and radiographic success of thrombectomy may be considered significant predictors for hemorrhagic conversion following AIS in patients who undergo mechanical thrombectomy.Disclosures A. Boyke: None. K. Javed: None. J. Dardick: None. I. Naidu: None. J. Ryvlin: None. D. Kadaba: None. N. Haranhalli: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Boyke, A., Javed, K., Dardick, J., Naidu, I., Ryvlin, J., Kadaba, D., Haranhalli, N. Tags: Electronic poster abstracts Source Type: research

European Stroke Organisation (ESO)-European Society for Minimally Invasive Neurological Therapy (ESMINT) expedited recommendation on indication for intravenous thrombolysis before mechanical thrombectomy in patients with acute ischemic stroke and anterior circulation large vessel occlusion
Six randomized controlled clinical trials have assessed whether mechanical thrombectomy (MT) alone is non-inferior to intravenous thrombolysis (IVT) plus MT within 4.5 hours of symptom onset in patients with anterior circulation large vessel occlusion (LVO) ischemic stroke and no contraindication to IVT. An expedited recommendation process was initiated by the European Stroke Organisation (ESO) and conducted with the European Society of Minimally Invasive Neurological Therapy (ESMINT) according to ESO standard operating procedure based on the GRADE system. We identified two relevant Population, Intervention, Comparator, Ou...
Source: Journal of NeuroInterventional Surgery - February 16, 2022 Category: Neurosurgery Authors: Turc, G., Tsivgoulis, G., Audebert, H. J., Boogaarts, H., Bhogal, P., De Marchis, G. M., Fonseca, A. C., Khatri, P., Mazighi, M., Perez de la Ossa, N., Schellinger, P. D., Strbian, D., Toni, D., White, P., Whiteley, W., Zini, A., van Zwam, W., Fiehler, J. Tags: Editor''s choice Standards Source Type: research

O-016 Outcomes after endovascular mechanical thrombectomy for low national institutes of health stroke scale (NIHSS): a multicenter study
ConclusionsMT is an effective and safe treatment for appropriately selected ischemic stroke patients presenting with low NIHSS. Diabetes and prior stroke are predictors of functional dependence at 90 days, and prior stroke is also associated with mortality, suggesting that MT should be offered judiciously to patients with these risk factors. Our findings signal the need for a randomized trial comparing MT versus medical management for LVO patients with low NIHSS.Disclosures I. Abecassis: 2; C; IschemaView (Rapid), Remedy Robotics. E. Almallouhi: None. R. Chalhoub: None. S. Kassab: None. E. Bass: None. D. Ding: None. I. Mai...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Abecassis, I., Almallouhi, E., Chalhoub, R., Kassab, S., Bass, E., Ding, D., Maier, I., Psychogios, M., Liman, J., Alawieh, A., Wolfe, S., Arthur, A., Kan, P., Kim, J., De Leacy, R., Osbun, J., Jabbour, P., Grossbereg, J., Park, M., Mascitelli, J., Levitt Tags: SNIS 19th annual meeting oral abstracts Source Type: research

O-028 Injury-site co-targeting of platelet adhesion and complement activation - a novel translational strategy for acute ischemic stroke management
ConclusionPsel-Crry is a novel approach to target both platelet aggregation and complement-mediated neuroinflammation after stroke resulting in improved neurological outcomes in murine MCAO. Further preclinical characterization of chronic outcomes is ongoing in anticipation for clinical development.Disclosures A. Alawieh: 1; C; Department of VA. 6; C; US Patent App. 17/335,355. S. Tomlinson: 1; C; Department of VA, NIH/NINDS. 4; C; Q3 Bio. 6; C; US Patent App. 17/335,355.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Alawieh, A., Tomlinson, S. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

E-038 Stroke registries and publication metrics in relation to registration and industry sponsorship
ConclusionsStroke registries generate a substantial amount of publications and citations in literature. Approximately two-thirds of all publications do not reach their expected number of citations. Those registered at clinicaltrials.gov have fewer citations than their unregistered counterparts. Industry-sponsored registries have a higher impact factor, reflecting their publications in more prominent journals, but are less cited than non-sponsored ones.Disclosures W. Khawar: None. A. Monteiro: None. O. Bolanos: 5; C; Medtronic. B. Donnelly: None. K. Snyder: 2; C; Boston Scientific, Canon Medical Systems USA, Inc., MicroVent...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Khawar, W., Monteiro, A., Bolanos, O., Donnelly, B., Snyder, K., Davies, J., Levy, E., Siddiqui, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

O-012 Relationship between clot composition and procedural results for ischemic stroke aspiration thrombectomy: subset analysis from the INSIGHT registry
ConclusionsClot removed during neuroendovascular procedures can differ in consistency and removability, leading to an increased focus on thrombus composition as a crucial variable for improving outcomes of ischemic stroke. In this study, good final revascularization (mTICI 2b-3 at the final angiogram) occurred after aspiration thrombectomy regardless of clot composition. Ongoing analysis of collected specimens is expected to provide valuable information regarding thrombus biology and etiology and to aid in diagnosis, prognosis, and drug development.Abstract O-012 Table 1Clot composition vs procedural results for ischemic s...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Kellner, C., Dabney, A., Baltan, S., Sohrabji, F., Pennypacker, K., Nanda, A., Woodward, K., Rivet, D., Fraser, J. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

P-013 The need for speed: reducing endovascular treatment times in ischemic stroke
ConclusionsImproving awareness of process expectations by meeting with stakeholders resulted in a substantial and sustainable decreases in median door to groin puncture and door to first pass times. Implementation of hospital-based PI multidisciplinary team initiatives helped improve our sites work flow and continued to improve our door to 1st pass times.Disclosures H. Shownkeen: None. A. Doerr: None. B. Fill: None. A. Mazumdar: None. D. Pandya: None. K. Buffo: None. A. Stacey: None. T. Iacob: None. L. Stanek: None. J. Carlson: None. L. Spellman: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Shownkeen, H., Doerr, A., Fill, B., Mazumdar, A., Pandya, D., Buffo, K., Stacey, A., Iacob, T., Stanek, L., Carlson, J., Spellman, L. Tags: SNIS 20th annual meeting oral poster abstracts Source Type: research

E-035 Stroke management and outcomes in low- and lower-middle-income countries: a meta-analysis of 8,535 patients
ConclusionsA severe healthcare disparity is present in low- and lower-middle-income countries where there is delayed diagnosis of strokes and increased rates of poor clinical outcomes for these patients.Disclosures A. Aguirre: None. J. Rodgers: None. T. Reardon: None. N. Brown: None. N. Shlobin: None. A. Ballatori: None. J. Gendreau: None. S. Shahrestani: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Aguirre, A., Rodgers, J., Reardon, T., Brown, N., Shlobin, N., Ballatori, A., Gendreau, J., Shahrestani, S. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

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