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P134/298 Endovascular therapy delay for acute large vessel occlusions is associated with worse functional outcome and increased mortality - Quantified
ConclusionShorter times to puncture and reperfusion impact mRS and mortality in LVO stroke patients. Adequate hospital protocols and education may lead to faster and more efficient stroke activations leading to a shorter time to MT and reperfusion. Goals of door-to-puncture must be established in order to achieve better outcome.Disclosure of InterestNothing to disclose
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Carrion-Penagos, J., Morsi, R. Z., Kothari, S., Desai, H., Tarabichi, A., Thind, S., Coleman, E., Brorson, J. R., Mendelson, S. J., Prabhakaran, S., Mansour, A., Hout, T. K. Tags: 2.1 ISCHEMIC - Logistics Source Type: research

P151/175 Direct aspiration with EMBOVAC - first clinical experience and clot composition (results the "PERFECT study)
ConclusionThis is the first clinical evaluation of EMBOVAC. Direct aspiration with EMBOVAC as first line therapy resulted in high rates of reperfusion and favorable clinical outcomes. Clot composition analysis can aid in better understanding of the stroke etiology and means for effective clot removal.Disclosure of InterestAcandis (OJ, CL, JF); Microvention (GM, CC, JF); Stryker (GM, CC, JF); Medtronic (GM, CC, JF); Surge2surgery (BG); MIVI (CC); Phenox (CL, JF); Penumbra (CL, JF); GSK (AS); German Ministry of Science & Education and Economy & Innovation, EU, Hamburgische Investitions-/Förderbank, Philips, B...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Lobotesis, K., Jansen, O., Marnat, G., Gory, B., Nordmeyer, H., Eckert, B., Alessandro, P., Cognard, C., Loehr, C., Bracco, S., Schaefer, A., Macera, A., Fiehler, J., Doyle, K., Piano, M. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

E-110 Bilateral hypoplasia of the internal carotid artery (ICA) and intracranial vasculopathy with 'moyamoya phenomenon in association with alagille syndrome
ConclusionThe educational value of our case lies not only in the rarity of the condition but also in the uniqueness of patient presentation. It would be a helpful addition to the existing literature on rare genetic syndromes with cerebral vasculature involvement.Abstract E-110 Figure 1Disclosures H. Shakeel: None. J. Gandhi: None. R. Singh: None. A. Graziano: None. R. Cerejo: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Shakeel, H., Gandhi, J., Singh, R., Graziano, A., Cerejo, R. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-161 Transradial arterial access for neurointervention: the basics, benefits, and tools
Transradial access (TRA) is a feasible method for interventional neurovascular procedures, gaining popularity after becoming the standard access route in cardiovascular interventions. While advantages of TRA include better safety, cost reduction, and patient experience, barriers include a narrow variety of dedicated equipment for radial to neurovascular target vessels, need for further training for physicians and fellows, and physician bias toward Transfemoral access (TFA) due to training and familiarity.This educational poster focuses on the general technical details of TRA, including discussion of the TRA and distal TRA ...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Kelly, C., Abbas, M., Harris, D., Abbas, M., Luqman, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

P-001 Residual in-stent carotid stenosis and cigarette smoking are predictors of restenosis after stenting (CAS)
ConclusionWe present the largest single-center data in the US to date on carotid artery stenosis treated with CAS, and factors associated with restenosis. Residual in-stent carotid stenosis and smoking history were independent predictors. Maximizing treatment of initial stenosis within stent for carefully selected patients and aggressive smoking cessation education are important steps in preventing future carotid restenosis.Abstract P-001 Figure 1Carotid restenosis after carotid arty tenting (%) by categories of degree of residual stenosis after initial procedure (a), and by cutpoint of 29% (b)Disclosures P. Lai: None. K. ...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Lai, P., Snyder, K., Baig, A., Khawar, W., Donnelly, B., Siddiqi, M., Kruk, M., Jacoby, W., Davies, J., Siddiqui, A., Levy, E. Tags: SNIS 20th annual meeting oral poster abstracts Source Type: research

O20 Thrombectomy for medium vessel occlusions: treatment effect of successful recanalization on long term functional outcome
ConclusionTICI 2b recanalization in MeVO increased probability of good outcome from 27% to 58%, TICI 3 recanalization did not further improve prognosis. Do you have any conflict of interest to declare?: YesConflict of Interest StatementHelge Kniep and Fabian Flottmann are consultants for Eppdata.Milani Deb-Chatterji has received research grants from the Werner Otto Stiftung.Götz Thomalla received fees as consultant from Acandis, Bayer, and Portola, and fees as lecturer from Acandis, Alexion, Amarin, Bayer, Boehringer-Ingelheim, BristolMyersSquibb, Daiichii Sankyo, Portola, and Stryker.Jens Fiehler received research...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Kniep, H., Bechstein, M., Broocks, G., Brekenfeld, C., Flottmann, F., Deb-Chatterji, M., Meyer, L., Hanning, U., Thomalla, G., Fiehler, J., Gellissen, S. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P46 How much of the improvement in functional outcome after successful recanalization is explained by follow-up infarct volume reduction?
Conclusions57% of the improvement of functional outcome after successful recanalization is explained by follow-up infarct volume reduction. Results reflect established pathophysiological assumptions and confirm the value of infarct volume as imaging endpoint in clinical trials.ReferencesBoers AMM, Jansen IGH, Brown S, et al. Mediation of the relationship between endovascular therapy and functional outcome by follow-up infarct volume in patients with acute ischemic stroke. Jama Neurology 2019;76:194–202. DOI: 10.1001/Jamaneurol.2018.3661 Do you have any conflict of interest to declare?: YesConflict of Interest Stateme...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Kniep, H., Meyer, L., Bechstein, M., Broocks, G., Austein, F., Brekenfeld, C., Flottmann, F., Deb-Chatterji, M., Thomalla, G., Hanning, U., Fiehler, J., Gellissen, S. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P83 The relationship of functional outcome after mechanical thrombectomy and serum glucose is partially mediated by edema formation
ConclusionEdema formation explains 15% of the total adverse effects of high blood glucose levels. Major pathways might include other direct effects of high blood glucose, such as altered vessel wall and thrombus characteristics and higher thrombogenicity of the cerebral blood flow.ReferencesThorén, M., et al. "Predictors for Cerebral Edema in Acute Ischemic Stroke Treated with Intravenous Thrombolysis." Stroke 2017;48(9): 2464–2471. Do you have any conflict of interest to declare?: YesConflict of Interest StatementHelge Kniep is a consultant for Eppdata.Jens Fiehler received research support from: German Minis...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Kniep, H., Meyer, L., Bechstein, M., Hanning, U., Fiehler, J., Broocks, G. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

E-132 A retrospective analysis of stroke code specificity in predicting acute ischemic events
ConclusionsThis retrospective analysis of stroke codes at MGUH during a 6-month period was 29% specific in predicting AIS. This is significantly lower than what was found in previous studies. Of stroke mimics, TME was the major etiology encompassing 43.6% of cases. The results of our study suggest additional stroke education may be needed for non-neurologists and ancillary staff to appropriately recognize stroke symptoms to better improve the utilization of hospital resources and provide appropriate and efficient care.Disclosures A. Mehta: None. J. Isaacson: None. N. Lightfoot: None. T. Kitani: None. F. Khan: None. T. Hash...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Mehta, A., Isaacson, J., Lightfoot, N., Kitani, T., Khan, F., Hashemzadeh, T., Dawson, K., Mayson, D., Stemer, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-137 Endovascular therapy delay for acute large vessel occlusion is associated with worse functional outcome and increased mortality
ConclusionShorter times to MT and reperfusion impact functional outcome and mortality in LVO stroke patients. This indicates that an adequate hospital protocol and continuous education may lead to faster and more efficient stroke activations leading to a shorter time to MT and eventual reperfusion. Goals of door-to-puncture must be established in order to achieve better outcomes.Disclosures J. Carrion-Penagos: None. R. Morsi: None. S. Thind: None. E. Coleman: None. J. Brorson: None. C. McKoy: None. S. Mendelson: None. S. Prabhakaran: None. A. Mansour: None. T. Kass-Hout: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Carrion-Penagos, J., Morsi, R., Thind, S., Coleman, E., Brorson, J., McKoy, C., Mendelson, S., Prabhakaran, S., Mansour, A., Kass-Hout, T. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

O-038 Sympathetic nervous system activation causes cerebral perfusion deficit and cerebral vasoconstriction in Swine
ConclusionIn swine, electrical stimulation of SCG results in reproducible cerebral vasoconstriction and perfusion deficit comparable to cerebral vasospasm. This can be inhibited by prior local anesthetic injection into the SCG, a possible therapeutic target for cerebral vasospasm.Abstract O-038 Figure 1CT perfusion scan (top row) coronel view of approximate fronto-temporal area of swine brain (outlined in white box) at baseline, with right SCG stimulation, with lidocainc + right SCG stimulation. Cerebral angiogram (bottom row) AP view of swine cranial artcrics at baseline, with right SCG stimulation, with lidocaine + right...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Kim, W., Samarage, M., Zarrin, D., Goel, K., Johnson, J., Wang, A., Colby, G. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

P-015 Implementation of a cognitive dysfunction screening protocol after aneurysmal subarachnoid hemorrhage
ConclusionWe successfully implemented an evidence-based screening protocol for cognitive dysfunction after aSAH. Most of these patients did exhibit cognitive dysfunction using the MoCA despite a good functional recovery, defined as mRS score <2. Screening only with the mRS is inadequate to identify the substantial cognitive dysfunction within this patient population. Further research is necessary to understand the impact of early cognitive intervention on long term outcomes for patients with cognitive impairment following aSAH.Disclosures N. Hall: None. J. Jackson: None. R. Chitale: None. M. Fusco: None. C. Considine: N...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Hall, N., Jackson, J., Chitale, R., Fusco, M., Considine, C., Froehler, M. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research

E-115 Identifying cognitive dysfunction after aneurysmal subarachnoid hemorrhage
ConclusionA brief, peer-led education session on cognitive dysfunction after aSAH improves knowledge of the problem and current recommendations in the literature for cognitive dysfunction after aSAH. Ongoing research is necessary to understand whether the education session and observed positive knowledge change translate to a change in practice and compliance with evidence-based recommendations for cognitive dysfunction screening after aSAH.Disclosures N. Hall: None. R. Chitale: None. M. Fusco: None. M. Froehler: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Hall, N., Chitale, R., Fusco, M., Froehler, M. Tags: Electronic poster abstracts Source Type: research

E-085 Interventional and diagnostic neuroradiology fellowship education in the COVID-19 era
ConclusionElective neurointerventional case numbers decreased as a result of the COVID-19 pandemic, particularly impacting the fourth quarter of the 2019-2020 academic year (April - June). Similarly, there was a sizable decrease in diagnostic neuroradiology case volume during this same time period. The decrease in procedural and diagnostic neuroradiology cases raised concerns regarding the educational experience for both diagnostic and neurointerventional radiology fellows. However, as a result of decreased case volume, fellowship education was rapidly augmented with a wide variety of online webinars, lectures, case confer...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Wilseck, Z., Bamezai, S., Novakovic, N., Copelan, A., Wilseck, J., Srinivasan, A., Pandey, A., Thompson, G., Gemmete, J., Chaudhary, N. Tags: Electronic poster abstracts Source Type: research

E-027 Matricidal cavernous aneurysms: a multicenter case series
Conclusion Matricidal aneurysms require careful consideration and planning. The restricted anatomy of the cavernous sinus can make successful execution of endovascular interventions difficult. Direct elastic compression of the parent artery does not respond to angioplasty and stenting the way that atherosclerotic stenosis does. Because of this, planning for possible parent vessel sacrifice is important. Abstract E-027 Table 1 Intended Treatments and Outcomes n Intended Treatment Failed Treatment (rate) All Patients 37 10 (27%) Flow Diversion 18 5 (28%) Parent Vessel Sacrifice 11 With Bypass 4 2 (50%) Without Bypass 7 0 ...
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Roberts, M., Nickele, C., Welch, B., Ban, V., Ringer, A., Kim, L., Levitt, M., Lanzino, G., Kan, P., Shallwani, H., Siddiqui, A., Elijovich, L., Arthur, A. Tags: Electronic Poster Abstracts Source Type: research

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