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Source: BMJ Open

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Total 555 results found since Jan 2013.

Factors associated with the longer-term unmet supportive care needs of stroke survivors in Ethiopia: a multicentre cross-sectional study
Conclusions There are significant longer-term unmet supportive care needs among adult stroke survivors. The factors associated with longer-term unmet supportive care needs were; having comorbidities, moderate and above level of disability according to the modified Rankin Scale score and unable to use the physiotherapy service. The development of appropriate services to address the longer-term unmet supportive care needs of stroke survivors is warranted.
Source: BMJ Open - January 31, 2022 Category: General Medicine Authors: Tamrat, E. G., Gufue, Z. H., Getachew, S., Yifru, Y. M., Gizaw, M. Tags: Open access, Neurology Source Type: research

Chronic high-altitude exposure and the epidemiology of ischaemic stroke: a systematic review
Conclusions This review suggests that the most robust studies are more likely to find that prolonged living at higher altitudes reduces the risk of developing stroke or dying from it. Increased irrigation due to angiogenesis and increased vascular perfusion might be the reason behind improved survival profiles among those living within this altitude range. In contrast, residing above 3500 m seems to be associated with an apparent increased risk of developing stroke, probably linked to the presence of polycythaemia and other associated factors such as increased blood viscosity.
Source: BMJ Open - April 29, 2022 Category: General Medicine Authors: Ortiz-Prado, E., Cordovez, S. P., Vasconez, E., Viscor, G., Roderick, P. Tags: Open access, Neurology Source Type: research

242 Large vessel occlusion stroke in an emergency call: A descriptive analysis of emergency calls for thrombectomy candidates
ConclusionIn the emergency calls for patients with paramedic-suspected large vessel occlusion, typical stroke symptoms were described. The severity of the stroke stood out by the patients’ inability to speak any words or remain standing. It is possible to further develop stroke dispatch protocols to recognise thrombectomy candidates already during an emergency call.Conflict of interestNone.FundingNone.
Source: BMJ Open - May 1, 2022 Category: General Medicine Authors: Vuorinen, P., Kiili, J., Alanko, E., Huhtala, H., Ollikainen, J., Setälä, P., Hoppu, S. Tags: Open access Dispatch and triage Source Type: research

Association between hospital volume, processes of care and outcomes after acute ischaemic stroke: a prospective observational study
Conclusions We found no significant associations between hospital volume, processes of care at the hospital, and mortality, recurrent stroke, and combined vascular events in patients with ischaemic stroke. However, hospital volume may be associated with poor outcome at 1 year.
Source: BMJ Open - June 9, 2022 Category: General Medicine Authors: Zhang, R., Liu, G., Pan, Y., Zhou, M., Wang, Y. Tags: Open access, Neurology Source Type: research

Effects of a nurse-led peer support intervention for stroke survivors: protocol for a randomised controlled trial
This study aims to develop a nurse-led peer support intervention for stroke survivors based on the Person–Environment–Occupation–Performance Model and evaluate its effects on the psychosocial outcomes of stroke survivors. Methods and analysis This is an assessor-blinded two-arm randomised controlled trial. A convenience sample of 120 stroke survivors will be recruited from two community centres and one rehabilitation unit in Yangzhou, a medium-sized city in eastern China, with 60 participants each in the intervention and control groups. The participants allocated to the intervention group will receive th...
Source: BMJ Open - June 10, 2022 Category: General Medicine Authors: Wan, X., Chau, J. P. C., Wu, Y., Xu, L., Gong, W. Tags: Open access, Rehabilitation medicine Source Type: research

Life satisfaction and its influencing factors of middle-aged and elderly stroke patients in China: a national cross-sectional survey
Conclusions Our study indicates the importance of improving the overall health of patients who had a stroke and mediating factors, such as pain management, and work ability, spouse and children relationship in improving the life satisfaction of patients in the poststroke rehabilitation.
Source: BMJ Open - August 3, 2022 Category: General Medicine Authors: Liu, Y., Liu, J., Zhou, S., Xu, X., Cheng, Y., Yi, Y., Zou, G. Tags: Open access, Public health Source Type: research

Scoping review protocol of the use of codesign methods in stroke intervention development
Introduction Codesign is an emerging research method to enhance intervention development by actively engaging non-researchers (eg, people who have had a stroke, caregivers and clinicians) in research. The involvement of non-researchers in research is becoming increasingly popular within health studies as it may produce more relevant and effective findings. The stroke population commonly exhibits challenges such as aphasia and cognitive changes that may limit their participation in codesign. However, the use of codesign within the stroke literature has not been comprehensively reviewed. This scoping review will determine: (...
Source: BMJ Open - November 21, 2022 Category: General Medicine Authors: Singh, H., Nelson, M. L., Martyniuk, J., Colquhoun, H., Munce, S., Cameron, J. I., Kokorelias, K. M., Pakkal, O., Kuluski, K. Tags: Open access, Health services research Source Type: research

Time intervals and distances travelled for prehospital ambulance stroke care: data from the randomised-controlled ambulance-based Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)
Conclusion We completed a large prehospital stroke trial involving a simple-to-administer intervention across multiple ambulance services. The time from onset to randomisation and modest distances travelled support the applicability of future large-scale paramedic-delivered ambulance-based stroke trials in urban and rural locations. Trial registration number ISRCTN26986053.
Source: BMJ Open - November 21, 2022 Category: General Medicine Authors: Dixon, M., Appleton, J. P., Scutt, P., Woodhouse, L. J., Haywood, L. J., Havard, D., Williams, J., Siriwardena, A. N., Bath, P. M., on behalf of the RIGHT-2 Investigators Tags: Open access, Neurology Source Type: research

Prevalence and distribution of lacunar stroke in China: a cross-sectional study using self-reported survey data
Conclusions In this study, the prevalence and distribution of lacunar stroke were reported at population level across China. Special attention and prevention should be given to the age, sex and geographical groups that are vulnerable to lacunar stroke.
Source: BMJ Open - December 30, 2022 Category: General Medicine Authors: Han, S., Sun, D., Jiang, B., Sun, H., Ru, X., Jin, A., Wang, Y., Wang, W. Tags: Open access, Neurology Source Type: research

Association between bilirubin levels and risk of stroke: a systematic review and meta-analysis
Conclusions Elevated bilirubin levels were associated with a decreased risk of stroke among adults. PROSPERO registration number CRD42017071497.
Source: BMJ Open - May 10, 2023 Category: General Medicine Authors: Wang, G., Qiao, L., Tang, Z., Zhou, S., Min, J., Li, M. Tags: Open access, Neurology Source Type: research

Stroke resource utilisation and all-cause mortality in Thailand 2017-2020: A retrospective, cross-sectional study
Conclusion The highest mean cost per patient was found in patients with haemorrhagic stroke. Receiving rehabilitation was associated with lower cost and mortality risk. Rehabilitation and disability outcomes should be improved to ensure an enhancement of health outcomes and efficient use of resources.
Source: BMJ Open - June 6, 2023 Category: General Medicine Authors: Kumluang, S., Wu, O., Langhorne, P., Geue, C. Tags: Open access, Health services research Source Type: research

RECREATE: a study protocol for a multicentre pilot cluster randomised controlled trial (cRCT) in UK stroke services evaluating an intervention to reduce sedentary behaviour in stroke survivors (Get Set Go) with embedded process and economic evaluations
This study is a pragmatic, multicentre, two-arm, external pilot cluster randomised controlled trial with embedded process and economic evaluations. UK-based stroke services will be randomised 1:1 to the intervention (usual care plus Get Set Go) or control (usual care) arm. Fifteen stroke services will recruit 300–400 stroke inpatient and carer participants, with follow-up at 6, 12 and 24 months. The proposed primary endpoint is stroke survivor self-reported Nottingham Extended Activities of Daily Living scale at 12 months. Endpoint analyses will be exploratory and provide preliminary estimates of intervention effect....
Source: BMJ Open - July 30, 2023 Category: General Medicine Authors: Airlie, J., Burton, L.-J., Copsey, B., English, C., Farrin, A., Fitzsimons, C. F., Holloway, I., Horrocks, J., Johansson, J. F., Mead, G., Moreau, L. A., Ozer, S., Patel, A., Yaziji, N., Forster, A., on behalf of the RECREATE Programme Management Group, A Tags: Open access, Rehabilitation medicine Source Type: research

Prevalence and risk factors of stroke in high-altitude areas: a systematic review and meta-analysis
Conclusions The findings of this study provide insights into the pooled prevalence of stroke in high-altitude areas, highlighting variations based on geographic regions and sampling type. Moreover, age, gender, hypertension and obesity were found to be associated with the occurrence of stroke. PROSPERO registration number CRD42022381541.
Source: BMJ Open - September 21, 2023 Category: General Medicine Authors: Zheng, B., Luo, Y., Li, Y., Gu, G., Jiang, J., Chen, C., Chen, Z., Wang, J. Tags: Open access, Neurology Source Type: research

Retrospective case review of missed opportunities for primary prevention of stroke and TIA in primary care: protocol paper
This study will investigate: (1) the proportion of strokes/TIAs with prior missed opportunities for prevention in primary care; (2) the influence of patient characteristics on missed prevention opportunities and (3) how the proportion of missed prevention opportunities has changed over time. Methods and analysis A retrospective case review will identify first-ever stroke and patients with TIA between 2000 and 2013 using anonymised electronic medical records extracted from the health improvement network (THIN) database. Four categories of missed opportunities for stroke/TIA prevention will be sought: untreated high blood p...
Source: BMJ Open - November 11, 2014 Category: Journals (General) Authors: Moran, G. M., Calvert, M., Feltham, M. G., Marshall, T. Tags: Open access, Cardiovascular medicine, Epidemiology, General practice / Family practice, Global health Protocol Source Type: research

Why do patients with stroke not receive the recommended amount of active therapy (ReAcT)? Study protocol for a multisite case study investigation
Introduction Increased frequency and intensity of inpatient therapy contributes to improved outcomes for stroke survivors. Differences exist in the amount of therapy provided internationally. In England, Wales and Northern Ireland it is recommended that a minimum of 45 min of each active therapy should be provided at least 5 days a week provided the therapy is appropriate and that the patient can tolerate this. Sentinel Stroke National Audit Programme (2014) data demonstrate this standard is not being achieved for most patients. No research been undertaken to explore how therapists in England manage their practic...
Source: BMJ Open - August 25, 2015 Category: Journals (General) Authors: Clarke, D. J., Tyson, S., Rodgers, H., Drummond, A., Palmer, R., Prescott, M., Tyrrell, P., Burton, L., Grenfell, K., Brkic, L., Forster, A. Tags: Open access, Health services research, Neurology, Qualitative research Protocol Source Type: research