Filtered By:
Source: BMJ Open

This page shows you your search results in order of relevance. This is page number 14.

Order by Relevance | Date

Total 555 results found since Jan 2013.

How common is isolated dysphasia among patients with stroke treated with intravenous thrombolysis, and what is their outcome? Results from the SITS-ISTR
Conclusions A low proportion of patients with isolated dysphasia are treated with IVT. Half of these patients were fully recovered at 7 days.
Source: BMJ Open - November 25, 2015 Category: Journals (General) Authors: Lundström, E., Zini, A., Wahlgren, N., Ahmed, N. Tags: Open access, Cardiovascular medicine, Neurology Research Source Type: research

Acupuncture for urinary incontinence after stroke: a protocol for systematic review
Introduction The aim of this study, which will include randomised controlled trials (RCTs), is to assess the efficacy and safety of acupuncture for patients with stroke and urinary incontinence. Methods and analysis RCTs will be searched electronically in the MEDLINE, EMBASE, Cochrane CENTRAL, CINAHL and four Chinese medical databases from their inception to present. Manual retrieval will also be conducted. RCTs will be included if acupuncture was evaluated as the sole or adjunct treatment for patients with stroke and urinary incontinence. The primary outcome will be measured by using the pad-weighing test. The secondary ...
Source: BMJ Open - February 23, 2016 Category: Journals (General) Authors: Sun, Z., Yu, N., Yue, J., Zhang, Q. Tags: Open access, Complementary medicine, Evidence based practice Protocol Source Type: research

Service factors causing delay in specialist assessment for TIA and minor stroke: a qualitative study of GP and patient perspectives
Conclusions Primary and emergency care providers need to review how they can best handle patients presenting with symptoms that could be due to stroke or TIA. In general practice, this may include receptionist training and/or triage by a nurse or doctor. Mechanisms need to be established to enable direct referral to the TIA clinic when patients whose symptoms have resolved present to other agencies. Further work is needed to improve diagnostic accuracy by non-specialists.
Source: BMJ Open - May 16, 2016 Category: Journals (General) Authors: Wilson, A., Coleby, D., Regen, E., Phelps, K., Windridge, K., Willars, J., Robinson, T. Tags: Open access, Cardiovascular medicine, Emergency medicine, Health services research, Qualitative research Source Type: research

Protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (ATTEND) in India
We describe the protocol for our process evaluation to encourage the development of in-process evaluation methodology and transparency in reporting. Methods and analysis The realist and RE-AIM (Reach, Effectiveness, Adoption, Implementation and Maintenance) frameworks informed the design. Mixed methods include semistructured interviews with health providers, patients and their carers, analysis of quantitative process data describing fidelity and dose of intervention, observations of trial set up and implementation, and the analysis of the cost data from the patients and their families perspective and programme budgets. Th...
Source: BMJ Open - September 14, 2016 Category: Journals (General) Authors: Liu, H., Lindley, R., Alim, M., Felix, C., Gandhi, D. B. C., Verma, S. J., Tugnawat, D. K., Syrigapu, A., Ramamurthy, R. K., Pandian, J. D., Walker, M., Forster, A., Anderson, C. S., Langhorne, P., Murthy, G. V. S., Shamanna, B. R., Hackett, M. L., Maulik Tags: Open access, Health services research, Rehabilitation medicine, Research methods Protocol Source Type: research

Community-based Rehabilitation Training after stroke: protocol of a pilot randomised controlled trial (ReTrain)
Introduction The Rehabilitation Training (ReTrain) intervention aims to improve functional mobility, adherence to poststroke exercise guidelines and quality of life for people after stroke. A definitive randomised controlled trial (RCT) is required to assess the clinical and cost-effectiveness of ReTrain, which is based on Action for Rehabilitation from Neurological Injury (ARNI). The purpose of this pilot study is to assess the feasibility of such a definitive trial and inform its design. Methods and analysis A 2-group, assessor-blinded, randomised controlled external pilot trial with parallel mixed-methods process evalu...
Source: BMJ Open - October 2, 2016 Category: Journals (General) Authors: Dean, S. G., Poltawski, L., Forster, A., Taylor, R. S., Spencer, A., James, M., Allison, R., Stevens, S., Norris, M., Shepherd, A. I., Calitri, R. Tags: Open access, Health services research, Rehabilitation medicine, Sports and exercise medicine Protocol Source Type: research

Early real-world evidence of persistence on oral anticoagulants for stroke prevention in non-valvular atrial fibrillation: a cohort study in UK primary care
Conclusions Observed differential prescribing of OACs can result in channelling bias in comparative effectiveness research. Persistence patterns changed over follow-up time, but there are indications of improved persistence rates with apixaban over other OACs in the UK. A larger study with longer follow-up is needed to corroborate findings. This study is registered on ClinicalTrials.gov (NCT02488421).
Source: BMJ Open - September 25, 2016 Category: Journals (General) Authors: Johnson, M. E., Lefevre, C., Collings, S.-L., Evans, D., Kloss, S., Ridha, E., Maguire, A. Tags: Open access, Cardiovascular medicine, Epidemiology, General practice / Family practice Research Source Type: research

Measurement properties of self-report physical activity assessment tools in stroke: a protocol for a systematic review
Discussion This systematic review will provide an extensive review of the measurement properties and clinical utility of self-report physical activity assessment tools used in individuals with stroke, which would benefit clinicians and researchers. Trial registration number PROSPERO CRD42016037146.
Source: BMJ Open - February 12, 2017 Category: Journals (General) Authors: Martins, J. C., Aguiar, L. T., Nadeau, S., Scianni, A. A., Teixeira-Salmela, L. F., Faria, C. D. C. d. M. Tags: Open access, Neurology, Rehabilitation medicine Protocol Source Type: research

154: a pharmacoeconomic evaluation to make decision: is the use of simvastatin 10 mg as an otc medication cost-effective for the primary prevention of stroke amongst women in iran?
Conclusion: In Iran no threshold has been determined but the results were compared with the threshold that WHO recommended (GDP per capita for Iran is $5442.9 for 2014 by World Bank). Considering this threshold, the evaluated intervention could be considered cost-effective.
Source: BMJ Open - February 7, 2017 Category: Journals (General) Authors: Amirsadri, M., Dorri, N. Tags: Open access Oral Source Type: research

1 The use and impact of 12-lead electrocardiograms in acute stroke patients: a systematic review
Conclusion Future studies should be based in the prehospital environment and should investigate whether undertaking an electrocardiogram in the prehospital setting affects clinical management decisions or has an association with mortality or morbidity. Conflict of interest None declared Funding This work was supported by School of Health Sciences PhD bursary – University of Surrey, and South East Coast Ambulance Service NHS Foundation Trust.
Source: BMJ Open - May 21, 2017 Category: General Medicine Authors: Munro, S., Quinn, T., Cooke, D., Joy, M. Source Type: research

Solution Focused Brief Therapy in Post-Stroke Aphasia (SOFIA): feasibility and acceptability results of a feasibility randomised wait-list controlled trial
Conclusion The high retention and adherence rates, alongside the qualitative data, suggest the study design was feasible and therapy approach acceptable even to people with severe aphasia. These results indicate a definitive randomised controlled trial of the intervention would be feasible. Trial registration number NCT03245060.
Source: BMJ Open - August 18, 2021 Category: General Medicine Authors: Northcott, S., Thomas, S., James, K., Simpson, A., Hirani, S., Barnard, R., Hilari, K. Tags: Open access, Rehabilitation medicine Source Type: research

Effect of occupational therapy home visit discharge planning on participation after stroke: protocol for the HOME Rehab trial
This study is approved by the Alfred Health Human Research Ethics Committee and site-specific ethics approval has been obtained at all participating sites. Results of the main trial and the secondary endpoint of cost-effectiveness will be submitted for publication in peer-reviewed journals Trial registration number ACTRN12618001360202
Source: BMJ Open - July 5, 2021 Category: General Medicine Authors: Lannin, N. A., Clemson, L., Drummond, A., Stanley, M., Churilov, L., Laver, K., O'Keefe, S., Cameron, I., Crotty, M., Usherwood, T., Andrew, N. E., Jolliffe, L., Cadilhac, D. A. Tags: Open access, Rehabilitation medicine Source Type: research

Prevalence of left atrial appendage thrombus in patients with acute ischaemic stroke and sinus rhythm: a cross-sectional study
Conclusions In patients with AIS and sinus rhythm on 12-lead ECG, our study revealed that the prevalence of LAA thrombus was 6.7% with the most prevalent aetiology being paroxysmal AF. The presence of SEC can be a predictor of LAA thrombus in these patients.
Source: BMJ Open - December 17, 2021 Category: General Medicine Authors: Nguyen, H. T., Nguyen, H. V. B., Nguyen, H. Q., Le, H. Q. Tags: Open access, Cardiovascular medicine Source Type: research

Repetitive transcranial magnetic stimulation for upper limb motor function and activities of daily living in patients with stroke: a protocol of a systematic review and Bayesian network meta-analysis
Introduction Patients with stroke usually suffer from varying degrees of movement dysfunction, which seriously affects their quality of life, especially for the upper limb dysfunction. Therefore, this study aims to compare the effects of different repetitive transcranial magnetic stimulation (rTMS) modalities on upper limb motor function and daily activities in patients with stroke. Methods and analysis Relevant research will be collected systematically from PubMed, Web of Science, Embase, Cochrane Library, ProQuest, Wanfang Database, China National Knowledge Infrastructure and Chinese Scientific and Journal Database (VIP...
Source: BMJ Open - March 10, 2022 Category: General Medicine Authors: Lu, Y., Xia, Y., Wu, Y., Pan, X., Wang, Z., Li, Y. Tags: Open access, Evidence based practice Source Type: research

Predictors of mortality in acute ischemic stroke treated with endovascular thrombectomy despite successful reperfusion: subgroup analysis of a multicentre randomised clinical trial
Conclusions Symptomatic ICH and high post-thrombectomy NIHSS score are strong predictor of 90-day mortality in acute ischaemic stroke treated with mechanical thrombectomy despite successful reperfusion, as well as high NIHSS score and high glucose level at hospital arrival. However, further studies need to be performed to confirm the association between smoking and mortality.
Source: BMJ Open - March 1, 2022 Category: General Medicine Authors: Li, H., Huang, J., Ye, S., Chen, H., Yuan, L., Liao, G., Du, W., Li, C., Fang, L., Liu, S., Yang, P., Zhang, Y., Xing, P., Zhang, X., Ye, X., Peng, Y., Cao, J., Zhang, L., Yang, Z., Liu, J., on behalf of the DIRECT-MT investigators, Yang, Zhang, Zhang, Zh Tags: Open access, Neurology Source Type: research

Development of strategies to support home-based exercise adherence after stroke: a Delphi consensus
Conclusion We developed a framework of comprehensive strategies to assist clinicians in supporting exercise adherence among stroke survivors. It provides practical methods that can be deployed in both research and clinical practices. Future studies should explore stakeholders’ experiences and the cost-effectiveness of implementing these strategies.
Source: BMJ Open - January 6, 2022 Category: General Medicine Authors: Mahmood, A., Deshmukh, A., Natarajan, M., Marsden, D., Vyslysel, G., Padickaparambil, S., TS, S., Direito, A., Kumaran, S., N, G., Sachdev, H., Kumar Veluswamy, S., Karthikbabu, S., Unnikrishnan, B., English, C., Solomon, J. M. Tags: Open access, Neurology Source Type: research