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Health inequalities in stroke and dementia prevention
Publication date: July 2020Source: The Lancet Neurology, Volume 19, Issue 7Author(s): Carol Brayne
Source: The Lancet Neurology - June 19, 2020 Category: Neurology Source Type: research

Small vessel disease: mechanisms and clinical implications
Publication date: Available online 13 May 2019Source: The Lancet NeurologyAuthor(s): Joanna M Wardlaw, Colin Smith, Martin DichgansSummarySmall vessel disease is a disorder of cerebral microvessels that causes white matter hyperintensities and several other common abnormalities (eg, recent small subcortical infarcts and lacunes) seen on brain imaging. Despite being a common cause of stroke and vascular dementia, the underlying pathogenesis is poorly understood. Research in humans has identified several manifestations of cerebral microvessel endothelial dysfunction including blood–brain barrier dysfunction, impaired vasod...
Source: The Lancet Neurology - May 14, 2019 Category: Neurology Source Type: research

Incidence and prevalence of dementia associated with transient ischaemic attack and stroke: analysis of the population-based Oxford Vascular Study
Publication date: March 2019Source: The Lancet Neurology, Volume 18, Issue 3Author(s): Sarah T Pendlebury, Peter M Rothwell, Oxford Vascular StudySummaryBackgroundRisk of dementia after stroke is a major concern for patients and carers. Reliable data for risk of dementia, particularly after transient ischaemic attack or minor stroke, are scarce. We studied the risks of, and risk factors for, dementia before and after transient ischaemic attack and stroke.MethodsThe Oxford Vascular Study is a prospective incidence study of all vascular events in a population of 92 728 people residing in Oxfordshire, UK. Patients with tran...
Source: The Lancet Neurology - February 14, 2019 Category: Neurology Source Type: research

Dementia risk after transient ischaemic attack and stroke
Publication date: March 2019Source: The Lancet Neurology, Volume 18, Issue 3Author(s): Martin Dichgans
Source: The Lancet Neurology - February 14, 2019 Category: Neurology Source Type: research

Music-based interventions in neurological rehabilitation
Publication date: Available online 26 June 2017 Source:The Lancet Neurology Author(s): Aleksi J Sihvonen, Teppo Särkämö, Vera Leo, Mari Tervaniemi, Eckart Altenmüller, Seppo Soinila During the past ten years, an increasing number of controlled studies have assessed the potential rehabilitative effects of music-based interventions, such as music listening, singing, or playing an instrument, in several neurological diseases. Although the number of studies and extent of available evidence is greatest in stroke and dementia, there is also evidence for the effects of music-based interventions on supporting cognition, motor...
Source: The Lancet Neurology - June 28, 2017 Category: Neurology Source Type: research

Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis
Publication date: January 2017 Source:The Lancet Neurology, Volume 16, Issue 1 Author(s): David J Irwin, Murray Grossman, Daniel Weintraub, Howard I Hurtig, John E Duda, Sharon X Xie, Edward B Lee, Vivianna M Van Deerlin, Oscar L Lopez, Julia K Kofler, Peter T Nelson, Gregory A Jicha, Randy Woltjer, Joseph F Quinn, Jeffery Kaye, James B Leverenz, Debby Tsuang, Katelan Longfellow, Dora Yearout, Walter Kukull, C Dirk Keene, Thomas J Montine, Cyrus P Zabetian, John Q Trojanowski Background Great heterogeneity exists in survival and the interval between onset of motor symptoms and dementia symptoms across synucleinopathies. W...
Source: The Lancet Neurology - December 6, 2016 Category: Neurology Source Type: research

The shared burden of stroke and dementia
Publication date: August 2016 Source:The Lancet Neurology, Volume 15, Issue 9 Author(s): The Lancet Neurology
Source: The Lancet Neurology - July 11, 2016 Category: Neurology Source Type: research

Dementia risk after spontaneous intracerebral haemorrhage: a prospective cohort study
Publication date: July 2016 Source:The Lancet Neurology, Volume 15, Issue 8 Author(s): Solène Moulin, Julien Labreuche, Stéphanie Bombois, Costanza Rossi, Gregoire Boulouis, Hilde Hénon, Alain Duhamel, Didier Leys, Charlotte Cordonnier Background Dementia occurs in at least 10% of patients within 1 year after stroke. However, the risk of dementia after spontaneous intracerebral haemorrhage that accounts for about 15% of all strokes has not been investigated in prospective studies. We aimed to determine the incidence of dementia and risk factors after an intracerebral haemorrhage. Methods We did a prospective...
Source: The Lancet Neurology - June 6, 2016 Category: Neurology Source Type: research

Dementia after stroke due to intracerebral haemorrhage
Publication date: July 2016 Source:The Lancet Neurology, Volume 15, Issue 8 Author(s): Rustam Al-Shahi Salman, Katie McGoohan, Mark Rodrigues, Martin Dichgans
Source: The Lancet Neurology - June 6, 2016 Category: Neurology Source Type: research

Preventing both stroke and dementia
Publication date: June 2016 Source:The Lancet Neurology, Volume 15, Issue 7 Author(s): Vladimir Hachinski, Luciano A Sposato, Moira Kapral
Source: The Lancet Neurology - May 11, 2016 Category: Neurology Source Type: research

Preventing both stroke and dementia – Authors' reply
Publication date: June 2016 Source:The Lancet Neurology, Volume 15, Issue 7 Author(s): Carol Brayne, Yu-Tzu Wu
Source: The Lancet Neurology - May 11, 2016 Category: Neurology Source Type: research