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Source: Journal of Clinical Neuroscience
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Total 29 results found since Jan 2013.
Clinical outcomes of moderate to severe acute ischemic stroke in a telemedicine network
The objective of this study was to analyze clinical and imaging based outcomes of moderate to severe stroke following treatment with thrombolysis, thrombectomy or a combination of both in a telemedicine network. Data of this retrospective study was abstracted from the institutional telestroke database. Patients with a National Institute of Health Stroke Scale score (NIH-SS ≥ 10) were included into the study. Primary outcome measure was the difference in NIH-SS at admission compared to discharge from the hospital. Secondary outcome measure was the discharge disposition defined as favorable (discharge to home or rehabi...
Source: Journal of Clinical Neuroscience - November 2, 2019 Category: Neuroscience Source Type: research
Can initial sarcopenia affect poststroke rehabilitation outcome?
This study investigated the association between the presence of sarcopenia, measured by nonhemiplegic grip strength, and the level of functional recovery, measured by the modified Rankin Scale (mRS) at six months after stroke. We performed a retrospective cohort analysis of a prospectively maintained database of 194 hemiplegic poststroke patients, who had been admitted to the Department of Rehabilitation Medicine of a university-affiliated hospital. At 6 months after stroke, 72.2% of patients had mRS score>3, with more women (81.0% vs. 66.0%, p = 0.024) showing poor recovery. Both men (51.3% vs. 35.9%, p = 0.041)...
Source: Journal of Clinical Neuroscience - September 6, 2019 Category: Neuroscience Source Type: research
Perioperative stroke associated in-hospital morbidity and in-hospital mortality in common non-vascular non-neurological surgery
This study identified perioperative stroke as an independent predictor of 30-day in-hospital morbidity and mortality following non-vascular, non-neurological surgery.
Source: Journal of Clinical Neuroscience - July 2, 2019 Category: Neuroscience Source Type: research
Risk factors for ischemic stroke post bone fracture
Publication date: Available online 7 November 2018Source: Journal of Clinical NeuroscienceAuthor(s): Qi An, Zhe Chen, Kang Huo, Hua Su, Qiu-Min QuAbstractStroke is one of the most devastating complications after bone fracture. However, due to the rarity of the complication, the risk factor for post fracture stroke remains unknown. We retrospectively reviewed 2914 fractured adults referred to the first affiliated hospital of Xi’an Jiaotong University, a regional referral center of China, from January 2008 to May 2013. As a result, among the 2914 patients, 13 of them had newly onset stroke within a median of 4 days after...
Source: Journal of Clinical Neuroscience - November 8, 2018 Category: Neuroscience Source Type: research
“In Safe Hands” – A costly integrated care program with limited benefits in stroke unit care
Publication date: Available online 6 November 2018Source: Journal of Clinical NeuroscienceAuthor(s): Sheila Jala, Sarah Giaccari, Melissa Passer, Carin Bertmar, Susan Day, Dayna Griffith, Martin KrauseAbstractGiven reported favourable outcomes of accountable care unit models of health care delivery (Taylor et al., 2017; Stein et al., 2015; Kara et al., 2015), the Clinical Excellence Commission of NSW has embraced “In Safe Hands” (ISH) to enhance coordination of care. ISH embraces the structured interdisciplinary bedside round (SIBR) component, for which reported outcomes include reduced length of stay (Taylor et al., 2...
Source: Journal of Clinical Neuroscience - November 6, 2018 Category: Neuroscience Source Type: research
Iron nanoparticle contrast enhanced microwave imaging for emergent stroke: A pilot study
Publication date: Available online 1 November 2018Source: Journal of Clinical NeuroscienceAuthor(s): Joseph S. Hudson, Timothy K. Chung, Benjamin S. Prout, Yasunori Nagahama, Madhavan L. Raghavan, David M. HasanAbstractEmergent stroke is mostly evaluated using hospital based imaging. Quick imaging allows for rapid administration of IV thrombolysis and outcome improvement. Microwave imaging (MI) is an emerging portable imaging modality. Iron oxide nanoparticles are known to interact with microwave frequency electromagnetic radiation. In this manuscript, we provide proof of concept for a novel iron oxide nanoparticle enhance...
Source: Journal of Clinical Neuroscience - November 2, 2018 Category: Neuroscience Source Type: research
Impact of venous thromboembolism during admission for meningioma surgery on hospital charges and postoperative complications
Publication date: Available online 9 October 2018Source: Journal of Clinical NeuroscienceAuthor(s): Eleonora F. Spinazzi, Darshan Shastri, Milap Raikundalia, Nicole A. Silva, Jean Anderson Eloy, James K. LiuAbstractSurgical resection of meningiomas has been associated with high rates of venous thromboembolic events (VTE) as compared with all other intracranial tumors. There is a paucity of data regarding the clinical complications and comorbidities associated with this cohort yet the underlying pathophysiological mechanism for this tumor-specific finding remains unclear. Our goal was to determine the various impacts of VTE...
Source: Journal of Clinical Neuroscience - October 9, 2018 Category: Neuroscience Source Type: research
Predictive value of plasma matrix metalloproteinase-9 concentrations for spontaneous haemorrhagic transformation in patients with acute ischaemic stroke: A cohort study in Chinese patients
Publication date: Available online 2 October 2018Source: Journal of Clinical NeuroscienceAuthor(s): Ruozhen Yuan, Song Tan, Deren Wang, Simiao Wu, Xinhui Cao, Shihong Zhang, Bo Wu, Ming LiuAbstractWhether matrix metalloproteinase 9 (MMP-9) concentrations in plasma predict risk of spontaneous haemorrhagic transformation (sHT) in acute ischaemic stroke is unclear. From 1 March 2003 to 27 February 2006, patients with acute ischaemic stroke admitted to West China Hospital within 24 h of onset and healthy controls were enrolled and blood samples obtained. Plasma MMP-9 concentrations were determined using enzyme-linked immunos...
Source: Journal of Clinical Neuroscience - October 4, 2018 Category: Neuroscience Source Type: research
Association of lower leukocyte count before thrombolysis with early neurological improvement in acute ischemic stroke patients
Publication date: Available online 17 August 2018Source: Journal of Clinical NeuroscienceAuthor(s): Canhui Tian, Zhong Ji, Wei Xiang, Xiaomei Huang, Shengnan Wang, Yongmin Wu, Suyue Pan, Liang Zhou, Zhen DengAbstractEarly neurological improvement (ENI) after thrombolysis in acute ischemic stroke is associated with a favorable long-term outcome. With the goal to evaluate ENI, we aimed to investigate whether ENI bears a relationship with routine blood tests before thrombolysis. A total of 240 patients with confirmed early ischemic stroke and intravenous recombinant tissue plasminogen activator (rtPA) treatment were enrolled ...
Source: Journal of Clinical Neuroscience - August 17, 2018 Category: Neuroscience Source Type: research
Survival after in-hospital cardiac arrest among cerebrovascular disease patients
Publication date: August 2018Source: Journal of Clinical Neuroscience, Volume 54Author(s): Corey R. Fehnel, Alissa Trepman, Dale Steele, Muhib A. Khan, Brian Silver, Susan L. MitchellAbstractStroke is a leading cause of death and disability, and while preferences for cardiopulmonary resuscitation (CPR) are frequently discussed, there is limited evidence detailing outcomes after CPR among acute cerebrovascular neurology (inclusive of stroke, subarachnoid hemorrhage (SAH)) patients. Systematic review and meta-analysis of PubMed and Cochrane libraries from January 1990 to December 2016 was conducted among stroke patients unde...
Source: Journal of Clinical Neuroscience - July 10, 2018 Category: Neuroscience Source Type: research
Dangers of outpatient nimodipine use after spontaneous subarachnoid hemorrhage in accordance with the Comprehensive Stroke Center guidelines
This report underscores the danger of outpatient nimodipine use and questions the optimal length of nimodipine therapy, especially in patients with low risk of vasospasm. Future studies, including randomized controlled trials and cost-effectiveness studies, are necessary to clarify the benefit of 21-day nimodipine therapy compared to a shortened duration of nimodipine.
Source: Journal of Clinical Neuroscience - April 12, 2018 Category: Neuroscience Source Type: research
Modified CHADS2 and CHA2DS2-VASc scores to predict atrial fibrillation in acute ischemic stroke patients
Publication date: Available online 23 February 2018 Source:Journal of Clinical Neuroscience Author(s): Rixia Liu, Xiaomeng Yang, Shuya Li, Yong Jiang, Yilong Wang, Yongjun Wang It is important to identify candidates who warrant extended cardiac monitoring after ischemic stroke. We investigated the predictive performance of the CHADS2 and CHA2DS2-VASc scores for previously unknown atrial fibrillation during in-hospital electrocardiographic monitoring. Patients were selected from a prospective trial in China. The clinical prediction of the scores was examined using the C statistic. Multivariate logistic regressions were per...
Source: Journal of Clinical Neuroscience - February 24, 2018 Category: Neuroscience Source Type: research
Clinical characteristics of patients with ischemic stroke following the 2016 Kumamoto earthquake
Publication date: December 2017 Source:Journal of Clinical Neuroscience, Volume 46 Author(s): Yuichiro Inatomi, Makoto Nakajima, Toshiro Yonehara, Yukio Ando To investigate the clinical characteristics of patients with ischemic stroke following the 2016 Kumamoto earthquake. We retrospectively studied patients with ischemic stroke admitted to our hospital for 12weeks following the earthquake. We compared the clinical backgrounds and characteristics of the patients: before (the same period from the previous 3years) and after the earthquake; and the early (first 2weeks) and late (subsequent 10weeks) phases. A total of 194 pa...
Source: Journal of Clinical Neuroscience - October 27, 2017 Category: Neuroscience Source Type: research
