• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – case report
Publication date: Available online 17 July 2020Source: Journal of Clinical NeuroscienceAuthor(s): Gustavo Celeira de Sousa, Thiago Celeira de Sousa, Marcelo Akira Kobayashi Sakiyama, Jeanne Seabra Negrão Lima da Silva, Emanuel de Jesus Soares de Sousa
Source: Journal of Clinical Neuroscience - July 19, 2020 Category: Neuroscience Source Type: research

Ischemic stroke caused by giant cell arteritis associated with pulmonary adenocarcinoma
We describe a 77-year-old man with a sudden onset of dizziness, vomiting, and gait disturbances. Following imaging studies, a diagnosis of bulbar ischemic stroke with left vertebral artery stenosis was made. Based on a history of polymyalgia rheumatica, on laboratory tests, and brain digital subtraction angiography, a diagnosis of GCA was advanced and the patient underwent high-dose steroidal therapy. After a total body 18-FGD PET imaging, a pulmonary adenocarcinoma was found.Vertebral artery involvement is a rare but important occurrence in GCA as it carries a high mortality rate, and may require a vigorous therapeutic ap...
Source: Journal of Clinical Neuroscience - November 5, 2019 Category: Neuroscience Source Type: research

A case of acute encephalophathy with residual neurological sequelae induced by immunoglobulin A vasculitis
In conclusion, acute encephalopathy with IgAV could cause neurological sequelae by prolonged seizure, and elevated IL-6 in CSF and laterality of cerebral blood flow in ASL might be useful to predict the prognosis of CNS dysfunction of IgAV.
Source: Journal of Clinical Neuroscience - June 12, 2019 Category: Neuroscience Source Type: research

Long-term utility and complication profile of open craniotomy for biopsy in patients with idiopathic encephalitis
Publication date: Available online 12 December 2016 Source:Journal of Clinical Neuroscience Author(s): Kalil G. Abdullah, Yin Li, Prateek Agarwal, Nikhil R. Nayak, Jayesh P. Thawani, Ramani Balu, Timothy H. Lucas Neurosurgeons are often asked to perform open biopsy for diagnosis of encephalitis after medical investigations are non-diagnostic. These patients may be critically ill with multiple comorbidities. Patients and their families often request data regarding the success rates and complication profile of biopsy, but minimal literature exists in this area. Retrospective chart review of all patients undergoing open brai...
Source: Journal of Clinical Neuroscience - December 11, 2016 Category: Neuroscience Source Type: research

Intravascular lymphoma mimicking vasculitis
This report documents the presence of intravascular lymphoma diagnosed on a brain biopsy in a 60-year-old man. He initially presented 6months before brain biopsy with chest pain and hypotension, warranting coronary artery bypass graft surgery. Four months later, he presented with signs attributed to a stroke (diaphoresis, slumped over in a chair and left hand weakness). He subsequently developed a sudden onset wide-based gait, left leg numbness, word finding difficulties and worsening confusion. A MRI study showed multiple infarcts in the brain, including cerebellum. Invasive angiogram suggested vasculitis. He was started ...
Source: Journal of Clinical Neuroscience - November 10, 2016 Category: Neuroscience Source Type: research

Pituitary aspergillus infection
We report a case of Aspergillus infection involving the pituitary gland and sellar region discovered in a 74-year-old man. The patient had a history of hypertension, chronic renal disease, autoimmune hemolytic anemia and presented with right eye pain, headaches and worsening hemiparesis. Imaging studies revealed a right internal carotid artery occlusion and an acute right pontine stroke along with smaller infarcts in the right middle cerebral artery distribution. Clinically, the patient was thought to have vasculitis. An infectious etiology was not identified. He developed respiratory distress and died. At autopsy, necroti...
Source: Journal of Clinical Neuroscience - May 29, 2016 Category: Neuroscience Source Type: research

Ten year clinical experience with stroke and cerebral vasculitis
Publication date: Available online 8 January 2016 Source:Journal of Clinical Neuroscience Author(s): Peter A. Kempster, Catriona A. McLean, Thanh G. Phan Angiitis of the central nervous system (CNS) is difficult to diagnose but potentially fatal. When stroke occurs in a younger individual or is associated with multiple infarcts on imaging, clinicians must decide how far to pursue a possible diagnosis of vasculitis. The aim of this study is to establish the prevalence of primary and secondary cerebral angiitis among patients presenting with stroke. Hospital attendances over a 10year period were surveyed by searching fo...
Source: Journal of Clinical Neuroscience - January 11, 2016 Category: Neuroscience Source Type: research

Minocycline-induced polyarteritis nodosa-like vasculitis presenting as brainstem stroke
This report shows that ischemic strokes may occur as a result of minocycline-induced vasculitis. While this is likely a rare association, recognition is important given the widespread use of minocycline and the potential for devastating consequences in a young population. Consequently, drug-induced vasculitis should be considered in patients with an ischemic stroke taking minocycline.
Source: Journal of Clinical Neuroscience - April 28, 2015 Category: Neuroscience Source Type: research