• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Prothrombotic State in Atrial Fibrillation Patients With One Additional Risk Factor of the CHA2DS2-VASc Score (Beyond Sex)
ConclusionsA prothrombotic state (increased thrombin generation, denser fibrin clots, impaired fibrinolysis, and endothelial injury) characterizes patients with AF with 1 additional clinical stroke risk factor (beyond sex), with age 65-74 years being particularly associated with prothrombotic indices.RésuméContexteLa question de savoir si un état prothrombotique survient chez les patients atteints de fibrillation auriculaire (FA) à faible risque d’accident vasculaire cérébral (AVC) n’a pas été élucidée.MéthodologieNous avons étudié 118 patients atteints de FA présentant un score CHA2DS2-VASc (insuffisance...
Source: Canadian Journal of Cardiology - April 27, 2019 Category: Cardiology Source Type: research

Factors Influencing Oral Anticoagulation Prescription for Patients Presenting to Emergency Departments With Atrial Fibrillation and Flutter
Publication date: June 2018Source: Canadian Journal of Cardiology, Volume 34, Issue 6Author(s): Robert J.H. Miller, Derek S. Chew, Saman Rezazadeh, Sheila Klassen, Payam Pournazari, Eddy Lang, F. Russell QuinnAbstractAtrial fibrillation and atrial flutter (AF/AFL) are associated with an increased risk of stroke and systemic embolism. However, many patients are not started on guideline-recommended oral anticoagulation (OAC). We determined factors associated with initiation of OAC in eligible patients presenting to emergency departments. This retrospective cohort included patients with electrocardiogram (ECG)-documented AF/A...
Source: Canadian Journal of Cardiology - July 10, 2018 Category: Cardiology Source Type: research

Efficacy of Calcium Channel Blockers on Major Cardiovascular Outcomes for the Treatment of Hypertension in Asian Populations: A Meta Analysis
Conclusion There is no evidence that dihydropyridine calcium channel blockers are superior to other antihypertensive agents in Asian populations for the treatment of hypertension. Teaser Whether calcium channel blockers exert a greater effect on cardiovascular risk reduction in Asian populations than other antihypertensive agents is unknown. We conducted a meta-analysis of hypertension trials of dihydropyridine calcium channel blockers in Asian populations to clarify this association. We noted no evidence that dihydropyridine calcium channel blockers are superior to other antihypertensive agents in Asian populations at red...
Source: Canadian Journal of Cardiology - January 20, 2017 Category: Cardiology Source Type: research

Recent temporal changes in atherosclerotic cardiovascular diseases in Ontario: Clinical and health systems impact
Conclusions Striking declines in hospitalizations and deaths from ASCVD were observed in Ontario from 1994-2014. However, the limited progress observed in younger Canadians highlights the need for ongoing efforts aimed at preventing and treating ASCVDs and their associated risk factors. Teaser As part of the Cardiovascular Health in Ambulatory Care Research Team “big data” initiative, we utilized information from population-based databases to examine 20-year temporal trends in hospitalizations and mortality attributed to atherosclerotic cardiovascular diseases (ASCVD). Overall, substantive declines in hospitalization a...
Source: Canadian Journal of Cardiology - November 15, 2016 Category: Cardiology Source Type: research

Left Atrial Appendage Closure for Atrial Fibrillation Is Safe and Effective After Intracranial or Intraocular Hemorrhage
Conclusions In our consecutive series, LAA closure was found to be safe and effective in patients with AF and a history of ICH or IOH.
Source: Canadian Journal of Cardiology - February 25, 2016 Category: Cardiology Source Type: research

Effect of Nocturnal Intermittent Hypoxia on Left Atrial Appendage Flow Velocity in Atrial Fibrillation
Conclusions Nocturnal intermittent hypoxia was an independent determinant for low LAA flow velocity in patients with AF, suggesting that the connection between SDB and LAA function might underlie the association of AF with stroke.
Source: Canadian Journal of Cardiology - June 23, 2015 Category: Cardiology Source Type: research

When to Suspect Sleep Apnea and What to Do About It
The objectives of treatment are to improve symptoms, quality of life, and cardiovascular outcomes. The mainstay of treatment for moderate-to-severe OSA is positive airway pressure (PAP). Automated PAP devices may be used in uncomplicated OSA, whereas continuous fixed PAP is the treatment of choice for other patients with OSA, and may also treat a proportion of patients with CSA-CSR. A form of bi-level PAP known as adaptive servoventilation is effective in treating a majority of patients with CSA-CSR.
Source: Canadian Journal of Cardiology - June 23, 2015 Category: Cardiology Source Type: research

“When to suspect sleep apnea and what to do about it”
This article provides an overview of the clinical signs and symptoms of sleep apnea, approaches to diagnostic testing and the main therapeutic strategies for both obstructive and central sleep apnea.”
Source: Canadian Journal of Cardiology - April 28, 2015 Category: Cardiology Source Type: research

Atrial Fibrillation Patients Categorized as “Not for Anticoagulation” According to the 2014 Canadian Cardiovascular Society Algorithm Are Not “Low Risk”
Conclusions Based on the 2014 CCS algorithm, the “OAC not recommended” subgroup can have a high 1-year stroke rate overall, showing that such patients are not “low risk.” Use of the ESC guideline approach (based on the CHA2DS2-VASc) offers refinement of stroke risk stratification in such patients.
Source: Canadian Journal of Cardiology - January 17, 2015 Category: Cardiology Source Type: research

Serum Uric Acid and Risk of Left Atrial Thrombus in Patients With Nonvalvular Atrial Fibrillation
Conclusions Hyperuricemia was a modest risk factor for LA thrombus, which might refine stratification of LA thrombus in patients with nonvalvular AF.
Source: Canadian Journal of Cardiology - November 4, 2014 Category: Cardiology Source Type: research