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Source: Translational Stroke Research
Education: Academia

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Total 3 results found since Jan 2013.

Long-Term Follow-Up of Cerebral Aneurysms Completely Occluded at 6  Months After Intervention with the Woven EndoBridge (WEB) Device: a Retrospective Multicenter Observational Study
This study underlines the importance of repeat imaging in patients treated with the WEB device even if complete occlusio n is achieved short term. Follow-up can be performed using DSA, MRA or CTA with no difference in positive predictive value.
Source: Translational Stroke Research - May 11, 2023 Category: Neurology Source Type: research

A Novel Partial MHC Class II Construct, DRmQ, Inhibits Central and Peripheral Inflammatory Responses to Promote Neuroprotection in Experimental Stroke
AbstractRecognizing that the pathologic progression of stroke is closely associated with aberrant immune responses, in particular the activation of peripheral leukocytes, namely T cells, we hypothesized that finding a treatment designed to inhibit neuroantigen-specific T cells and block cytotoxic monocytes and macrophages may render therapeutic effects in stroke. We previously reported that subcutaneous administration of partial MHC class II constructs promote behavioral and histological effects in stroke mice by centrally promoting a protective M2 macrophage/microglia phenotype in the CNS and peripherally reversing stroke...
Source: Translational Stroke Research - December 2, 2019 Category: Neurology Source Type: research

Academic-industry Collaborations in Translational Stroke Research
Abstract Academic-industry collaborations are an emerging format of translational stroke research. Next to classic contract research models, a multitude of collaboration models has been developed, some of which even allowing for multinational or intercontinental research programs. This development has recently been paralleled by first successful attempts to overcome the translational stroke research road block, such as the unprecedented success of novel endovascular approaches or the advent of the multicenter preclinical trial concept. While the first underlines the role of the industry as a major innovation drive...
Source: Translational Stroke Research - June 13, 2016 Category: Neurology Source Type: research