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Source: JAHA:Journal of the American Heart Association
Condition: Coronary Heart Disease

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Total 70 results found since Jan 2013.

Folic Acid Supplementation and the Risk of Cardiovascular Diseases: A Meta-Analysis of Randomized Controlled Trials Epidemiology
BackgroundResults from observational and genetic epidemiological studies suggest that lower serum homocysteine levels are associated with lower incidence of cardiovascular disease (CVD). Numerous randomized controlled trials have investigated the efficacy of lowering homocysteine with folic acid supplementation for CVD risk, but conflicting results have been reported.Methods and ResultsThree bibliographic databases (Medline, Embase, and the Cochrane Database of Systematic Reviews) were searched from database inception until December 1, 2015. Of the 1933 references reviewed for eligibility, 30 randomized controlled trials i...
Source: JAHA:Journal of the American Heart Association - August 14, 2016 Category: Cardiology Authors: Li, Y., Huang, T., Zheng, Y., Muka, T., Troup, J., Hu, F. B. Tags: Cardiovascular Disease, Diet and Nutrition Original Research Source Type: research

Elucidating the Association Between Depressive Symptoms, Coronary Heart Disease, and Stroke in Black and White Adults: The REasons for Geographic And Racial Differences in Stroke (REGARDS) Study Epidemiology
Conclusions Proximal depressive symptoms were associated with incident fatal and nonfatal stroke and CVD death even after controlling for multiple explanatory factors, further supporting the urgent need for timely management of depressive symptoms.
Source: JAHA:Journal of the American Heart Association - August 11, 2016 Category: Cardiology Authors: Moise, N., Khodneva, Y., Richman, J., Shimbo, D., Kronish, I., Safford, M. M. Tags: Quality and Outcomes Epidemiology Source Type: research

Obesity and Subtypes of Incident Cardiovascular Disease Epidemiology
Conclusions The link between obesity and HF was stronger than those for other CVD subtypes and was uniquely unexplained by traditional risk factors. Weight management is likely critical for optimal HF prevention, and nontraditional pathways linking obesity to HF need to be elucidated.
Source: JAHA:Journal of the American Heart Association - July 27, 2016 Category: Cardiology Authors: Ndumele, C. E., Matsushita, K., Lazo, M., Bello, N., Blumenthal, R. S., Gerstenblith, G., Nambi, V., Ballantyne, C. M., Solomon, S. D., Selvin, E., Folsom, A. R., Coresh, J. Tags: Cardiovascular Disease, Epidemiology, Obesity Source Type: research

Nocturnal Hypoxemia Due to Obstructive Sleep Apnea Is an Independent Predictor of Poor Prognosis After Myocardial Infarction Coronary Heart Disease
ConclusionsNocturnal hypoxemia in OSA is an important predictor of poor prognosis for patients after MI. These findings suggest that routine use of low‐cost nocturnal oximetry may be an economical and practical approach to stratify risk in post‐MI patients.
Source: JAHA:Journal of the American Heart Association - July 26, 2016 Category: Cardiology Authors: Xie, J., Sert Kuniyoshi, F. H., Covassin, N., Singh, P., Gami, A. S., Wang, S., Chahal, C. A. A., Wei, Y., Somers, V. K. Tags: Risk Factors, Acute Coronary Syndromes Original Research Source Type: research

Reduced Kidney Function Is Associated With Cardiometabolic Risk Factors, Prevalent and Predicted Risk of Cardiovascular Disease in Chinese Adults: Results From the REACTION Study Kidney in Cardiovascular Disease
Conclusions Even mildly reduced eGFR (under 90 mL/min per 1.73 m2) is associated with elevated 10-year Framingham risk for CHD and 10-year ASCVD risk among Chinese adults.
Source: JAHA:Journal of the American Heart Association - July 21, 2016 Category: Cardiology Authors: Lu, J., Mu, Y., Su, Q., Shi, L., Liu, C., Zhao, J., Chen, L., Li, Q., Yang, T., Yan, L., Wan, Q., Wu, S., Liu, Y., Wang, G., Luo, Z., Tang, X., Chen, G., Huo, Y., Gao, Z., Ye, Z., Wang, Y., Qin, G., Deng, H., Yu, X., Shen, F., Chen, L., Zhao, L., Sun, J., Tags: Cardiovascular Disease, Epidemiology, Lifestyle, Risk Factors Kidney in Cardiovascular Disease Source Type: research

Universal Classification System Type of Incident Myocardial Infarction in Patients With Stable Atherosclerosis: Observations From Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2{degrees}P)-TIMI 50 Coronary Heart Disease
Conclusions Among stable patients with established atherosclerosis, the most common type of incident MI is spontaneous MI, and the reduction in MI with vorapaxar was consistent across MIs of varying type and size, including spontaneous infarctions ≥10x upper reference limit. Clinical Trial Registration URL: https://www.clinicaltrials.gov. Unique identifier: NCT00526474.
Source: JAHA:Journal of the American Heart Association - July 17, 2016 Category: Cardiology Authors: Kidd, S. K., Bonaca, M. P., Braunwald, E., De Ferrari, G. M., Lewis, B. S., Merlini, P. A., Murphy, S. A., Scirica, B. M., White, H. D., Morrow, D. A. Tags: Clinical Studies, Ischemia, Platelets Coronary Heart Disease Source Type: research

Lipoprotein-Associated Phospholipase A2 Activity Is a Marker of Risk But Not a Useful Target for Treatment in Patients With Stable Coronary Heart Disease Coronary Heart Disease
Conclusions Although high Lp-PLA2 activity was associated with increased risk of cardiovascular events, pharmacological lowering of Lp-PLA2 activity by 65% did not significantly reduce cardiovascular events in patients with stable coronary heart disease, regardless of the baseline level or the magnitude of change of Lp-PLA2 activity. Clinical Trial Registration URL: https://www.clinicaltrials.gov. Unique identifier: NCT00799903.
Source: JAHA:Journal of the American Heart Association - June 20, 2016 Category: Cardiology Authors: Wallentin, L., Held, C., Armstrong, P. W., Cannon, C. P., Davies, R. Y., Granger, C. B., Hagström, E., Harrington, R. A., Hochman, J. S., Koenig, W., Krug-Gourley, S., Mohler, E. R., Siegbahn, A., Tarka, E., Steg, P. G., Stewart, R. A. H., Weiss, Tags: Biomarkers, Risk Factors, Pharmacology, Treatment, Coronary Artery Disease Coronary Heart Disease Source Type: research

Impact of Sleep-Disordered Breathing on Long-Term Outcomes in Patients With Acute Coronary Syndrome Who Have Undergone Primary Percutaneous Coronary Intervention Coronary Heart Disease
Conclusions The study's results showed that the presence of SDB among patients with acute coronary syndrome following primary percutaneous coronary intervention is associated with a higher incidence of major adverse cardiocerebrovascular events during long-term follow-up.
Source: JAHA:Journal of the American Heart Association - June 14, 2016 Category: Cardiology Authors: Mazaki, T., Kasai, T., Yokoi, H., Kuramitsu, S., Yamaji, K., Morinaga, T., Masuda, H., Shirai, S., Ando, K. Tags: Risk Factors, Quality and Outcomes, Acute Coronary Syndromes Coronary Heart Disease Source Type: research

Circulating Levels of IL-6 Receptor and gp130 and Long-Term Clinical Outcomes in ST-Elevation Myocardial Infarction Coronary Heart Disease
Conclusion High levels of sIL-6R were associated with future cardiovascular events and mortality in STEMI patients, suggesting an important role of the IL-6 signaling system.
Source: JAHA:Journal of the American Heart Association - June 12, 2016 Category: Cardiology Authors: Ritschel, V. N., Seljeflot, I., Arnesen, H., Halvorsen, S., Eritsland, J., Fagerland, M. W., Andersen, G. O. Tags: Biomarkers, Inflammation, Ischemia Coronary Heart Disease Source Type: research

Low Homoarginine Levels in the Prognosis of Patients With Acute Chest Pain Coronary Heart Disease
Conclusion Low plasma homoarginine was identified as a risk marker for incident MACEs in patients with acute chest pain, in particular, in those with elevated hsTnI. Impaired homoarginine was associated with prevalent AF. Further studies are needed to investigate the link to AF and evaluate homoarginine as a therapeutic option for these patients.
Source: JAHA:Journal of the American Heart Association - April 12, 2016 Category: Cardiology Authors: Atzler, D., Baum, C., Ojeda, F., Keller, T., Cordts, K., Schnabel, R. B., Choe, C.-u., Lackner, K. J., Münzel, T., Böger, R. H., Blankenberg, S., Schwedhelm, E., Zeller, T. Tags: Atrial Fibrillation, Biomarkers, Endothelium/Vascular Type/Nitric Oxide, Acute Coronary Syndromes Coronary Heart Disease Source Type: research

Dietary {alpha}-Linolenic Acid, Marine {omega}-3 Fatty Acids, and Mortality in a Population With High Fish Consumption: Findings From the PREvencion con DIeta MEDiterranea (PREDIMED) Study Epidemiology
Conclusions In participants without prior cardiovascular disease and high fish consumption, dietary ALA, supplied mainly by walnuts and olive oil, relates inversely to all-cause mortality, whereas protection from cardiac mortality is limited to fish-derived long-chain n-3 polyunsaturated fatty acids. Clinical Trial Registration URL: http://www.Controlled-trials.com/. Unique identifier: ISRCTN35739639.
Source: JAHA:Journal of the American Heart Association - January 26, 2016 Category: Cardiology Authors: Sala-Vila, A., Guasch-Ferre, M., Hu, F. B., Sanchez-Tainta, A., Bullo, M., Serra-Mir, M., Lopez-Sabater, C., Sorli, J. V., Aros, F., Fiol, M., Munoz, M. A., Serra-Majem, L., Martinez, J. A., Corella, D., Fito, M., Salas-Salvado, J., Martinez-Gonzalez, M. Tags: Diet and Nutrition Epidemiology Source Type: research