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Abstract 385: The Impact of Aspirin Primary Prevention Treatment Guidelines: Temporal Trends in Aspirin Use for Primary vs Secondary Prevention, 2005-2013 Session Title: Poster Session III
Conclusion: Secondary prevention ASA use in primary care settings remains high, but ASA use for primary prevention of cardiovascular events is low. Despite creation of national guidelines, aspirin use in the PP population is half the rate of ASA use for secondary prevention. Additional methods to safely and effectively disseminate this primary prevention aspirin use recommendation, targeting both the public and health care providers, are warranted.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Van't Hof, J. R., Oldenburg, N., Duval, S., Dronca, S., Olson, A., Peterson, K., Leupker, R. V., Miller, K., Hirsch, A. T. Tags: Session Title: Poster Session III Source Type: research

The Effect of an EDTA-based Chelation Regimen on Patients With Diabetes Mellitus and Prior Myocardial Infarction in the Trial to Assess Chelation Therapy (TACT) Original Articles
Conclusions— Post–myocardial infarction patients with diabetes mellitus aged ≥50 demonstrated a marked reduction in cardiovascular events with EDTA chelation. These findings support efforts to replicate these findings and define the mechanisms of benefit. However, they do not constitute sufficient evidence to indicate the routine use of chelation therapy for all post–myocardial infarction patients with diabetes mellitus. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00044213.
Source: Circulation: Cardiovascular Quality and Outcomes - January 21, 2014 Category: Cardiology Authors: Escolar, E., Lamas, G. A., Mark, D. B., Boineau, R., Goertz, C., Rosenberg, Y., Nahin, R. L., Ouyang, P., Rozema, T., Magaziner, A., Nahas, R., Lewis, E. F., Lindblad, L., Lee, K. L. Tags: Cardiovascular Pharmacology, Secondary prevention, Type 2 diabetes, Chronic ischemic heart disease, Oxidant stress Original Articles Source Type: research

Risk of Ischemic Stroke After an Acute Myocardial Infarction in Patients With Diabetes Mellitus Original Articles
Conclusions— Ischemic stroke is a fairly common complication after an AMI in patients with diabetes mellitus, but the risk of stroke has decreased during recent years. The increased use of evidence-based therapies contributes importantly to this risk reduction, but there is still room for improvement.
Source: Circulation: Cardiovascular Quality and Outcomes - January 21, 2014 Category: Cardiology Authors: Jakobsson, S., Bergstrom, L., Bjorklund, F., Jernberg, T., Soderstrom, L., Mooe, T. Tags: Secondary prevention, Type 1 diabetes, Type 2 diabetes, Acute myocardial infarction, Acute Cerebral Infarction Original Articles Source Type: research

Risks and Benefits of Anticoagulation in Atrial Fibrillation: Insights From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Registry Original Articles
Conclusions— In community-based outpatients with AF, use of OAC was high and driven by not only predominantly stroke but also bleeding risk. Stroke risk significantly affects OAC use among those with low bleeding risk, whereas those with high bleeding risk demonstrate consistently lower use of OAC regardless of stroke risk.
Source: Circulation: Cardiovascular Quality and Outcomes - July 16, 2013 Category: Cardiology Authors: Cullen, M. W., Kim, S., Piccini, J. P., Ansell, J. E., Fonarow, G. C., Hylek, E. M., Singer, D. E., Mahaffey, K. W., Kowey, P. R., Thomas, L., Go, A. S., Lopes, R. D., Chang, P., Peterson, E. D., Gersh, B. J., on behalf of the ORBIT-AF Investigators Tags: Coumarins, Arrhythmias, clinical electrophysiology, drugs, Embolic stroke, Risk Factors for Stroke, Anticoagulants Original Articles Source Type: research

Abstract 24: Current Quality of Cardiovascular Prevention for Million Hearts™: An Analysis of 115,737 Outpatients from The Guideline Advantage™ Concurrent III Session A: Oral Abstract Presentations on EHS & Health IT
Conclusions: Compliance with clinical quality measures for the Million Hearts™ initiative varies widely across outpatient practices. Our findings identify multiple opportunities to improve the quality of outpatient care for cardiovascular prevention.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Eapen, Z., Bufalino, V., Peterson, E., Hernandez, A. Tags: Concurrent III Session A: Oral Abstract Presentations on EHS & amp; Health IT Source Type: research

Abstract 31: Patterns Of Healthcare Resource Utilization Among Adults With Type 2 Diabetes Mellitus At Risk Of Cardiovascular Events In The Large Population-based Study To Help Improve Early Evaluation And Management Of Risk Factors Leading To Diabetes (SHIELD) Poster Session I
Conclusions: CVD events among T2DM patients continue to represent a very high economic burden on the healthcare system. HRU is very high among adults with T2DM at-risk of CVD events and significantly higher among those who had a new CVD event within 3 and 5 years compared with those who did not have a new CVD event.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Fox, K. M., Wu, Y., Kim, J., Grandy, S. Tags: Poster Session I Source Type: research

Abstract 47: Presentation and Outcomes of Women Veterans with Suspected Ischemia and Nonobstructive Coronary Artery Disease: Insights from the VA Clinical Assessment Reporting and Tracking Program. Poster Session I
Conclusion: Between October 2007 and September 2011, 23% of women veterans undergoing catheterization for suspected ischemia had non-obstructive CAD. In contrast to non-VA studies, adverse clinical outcomes and re-hospitalization rates for chest pain were less frequent. These findings may represent systematic differences in treatment and follow-up care of women veterans between VA and non-VA healthcare systems.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Nkonde-Price, C., Plomondon, M., Maddox, T. M., Rumsfeld, J., Duvernoy, C. Tags: Poster Session I Source Type: research

Abstract 50: Cardiovascular Event Rates Among Adults with Type 2 Diabetes Mellitus at Risk of Cardiovascular Events in the Large Population-based Study to Help Improve Early Evaluation and Management of Risk Factors Leading to Diabetes (SHIELD) Poster Session I
Conclusions: T2DM individuals at risk for CVD events had significant incidence of MI, stroke, and revascularization in this large US population-based study. T2DM adults with established CVD are at higher risk of CVD events than those with no CVD but have multiple risk factors.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Fox, K. M., Wu, Y., Kim, J., Grandy, S. Tags: Poster Session I Source Type: research

Abstract 53: Health Care Utilization and Cost among Type 2 Diabetes Mellitus (T2DM) Patients with Cardiovascular Disease (CVD) or Cardiovascular Disease Risk Factors Poster Session I
CV events among T2DM patients are major contributors to high healthcare utilization and cost. Healthcare utilization and costs among T2DM patients with established CVD and CVD risk factors in a large US database were explored.T2DM patients aged ≥40 years were identified from the HealthCore Integrated Research Environment from 1/1/2007 to 4/30/2011 and followed from first T2DM diagnosis (index date) until loss of eligibility or death. Established CVD [Group 1] included patients with MI, stroke, peripheral vascular disease, coronary heart disease, congestive heart failure, or revascularization in the year prior to index. ...
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Kern, D. M., DeVore, S., Kim, J., Wu, Y., Tunceli, O., Wu, B., Hirshberg, B. Tags: Poster Session I Source Type: research

Abstract 59: Prevalence of Major Cardiovascular Risk Factors and Cardiovascular Diseases Among Vulnerable Population of a Safety Net Hospital Poster Session I
In conclusion, findings from the study demonstrate the pervasive burden of CVD risk factors in vulnerable groups compared with the national trends. These data may enhance the impetus to implement interventions to lower burden of CVD risk factors among overall and targeted at-risk groups, as well as develop strategies to prevent future development of adverse CVD risk factors starting at the youngest age.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Katsouli, A., Pandey, T., Goldberg, D. Tags: Poster Session I Source Type: research

Abstract 63: The Smoking Paradox in Patients Hospitalized with Coronary Artery Disease: Findings from Get With The Guidelines - CAD Poster Session I
Conclusion: Smoking continues to be a major risk factor for presenting with CAD at a much younger age and with fewer risk factors. It is likely that the continued modest association with lower in-hospital mortality in smokers in this analysis after adjustment reflects residual or unmeasured confounding. This apparent smoker’s paradox in CAD should not be interpreted as a benefit of cigarette smoking.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Ali, S. F., Smith, E. E., Bhatt, D. L., Pan, W., Fonarow, G. C., Schwamm, L. H. Tags: Poster Session I Source Type: research

Abstract 65: Identifying and Adapting a Prognostic Risk Equation for Relevant Subpopulations in a Pharmacoeconomic Model of Major Adverse Cardiovascular Event Prevention Poster Session I
Conclusions: Estimating the ratio of absolute risks for specific populations and subsets using QRISK2 can help a model to predict the value of targeting relevant subpopulations for a new treatment. When this risk adjustment is included in a lifetime model, additional benefits from secondary prevention, and increased likelihood that a treatment is cost effective in a UK context, can also be estimated. For non-UK populations, calibration of QRISK2 is needed or an alternative equation must be used.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Ariely, R., Klein, R., Tham, W.-K., Bell, C., Smolen, L., Tynan, A. Tags: Poster Session I Source Type: research

Abstract 96: Sex Differences in Pre-Event Health Status of Young Patients with Acute Myocardial Infarction: The VIRGO Study Poster Session I
Conclusion: Compared with men, young women presenting with an AMI seem to have worse health status with poorer physical functioning and quality of life prior to their event. In light of these findings, it may be useful for healthcare providers to identify young women who are at increased cardiovascular risk at an earlier stage in order to optimize their health status.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Dreyer, R. P., Smolderen, K. G., Strait, K. M., Beltrame, J. F., Lichtman, J. H., Lorenze, N. P., D'Onofrio, G., Krumholz, H. M., Spertus, J. A. Tags: Poster Session I Source Type: research

Abstract 150: Resource Utilization Patterns and Outcomes Among Acute Coronary Syndrome Patients: Findings From a Multi-Payer Analysis Poster Session II
Conclusion: These findings suggest that many patients with ACS do not receive appropriate recommended antithrombotic prophylaxis, and opportunities exist to improve therapy. Increased use of software tools such as AQuA may support enhanced education efforts aimed at improving adherence to guidelines and quality of care.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Lang, K., Bozkaya, D., Patel, A. A., Macomson, B., Crivera, C., Owens, G., Mody, S. Tags: Poster Session II Source Type: research

Abstract 156: Body Mass Index and Outcomes among Patients with Atrial Fibrillation from the ATRIA2-CVRN Study Poster Session II
In conclusion, overweight and moderate obesity appear protective for all-cause mortality in at-risk AF patients during off-warfarin periods, but these effects do not appear to be mediated by reduced risk of thromboembolism or major bleeding.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Black, M. H., Wu, J., Singer, D. E., Udaltsova, N., Harrison, T. N., Shen, A. Y.-J., Fang, M. C., Go, A. S., Reynolds, K. Tags: Poster Session II Source Type: research

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